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    CHUP1 Hydroxyproline-rich glycoprotein family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822157, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CHUP1
    Official Full Name
    Hydroxyproline-rich glycoprotein family protein
    Primary source
    TAIR:AT3G25690
    Locus tag
    AT3G25690
    See related
    Araport:AT3G25690
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    Arabidopsis thaliana CHLOROPLAST UNUSUAL POSITIONING 1; AtCHUP1; CHLOROPLAST UNUSUAL POSITIONING 1
    Summary
    actin binding protein required for normal chloroplast positioning
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    Genomic context

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    See CHUP1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    11
    Sequence:
    Chromosome: 3; NC_003074.8 (9352444..9357953)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Leucine-rich repeat (LRR) family protein Neighboring gene SLH domain protein Neighboring gene Eukaryotic aspartyl protease family protein Neighboring gene basic helix-loop-helix 32

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CHLOROPLAST UNUSUAL POSITIONING 1 is a plant-specific actin polymerization factor regulating chloroplast movement. Kong SG, et al. Plant Cell, 2024 Mar 29. PMID 38134410, Free PMC Article
    2. The functional domains of the chloroplast unusual positioning protein 1. Lehmann P, et al. Plant Sci, 2011 Apr. PMID 21421414
    3. The chloroplast outer membrane protein CHUP1 interacts with actin and profilin. Schmidt von Braun S, et al. Planta, 2008 Apr. PMID 18193273
    4. FKF1 Interacts with CHUP1 and Regulates Chloroplast Movement in Arabidopsis. Yuan N, et al. Plants (Basel), 2023 Jan 25. PMID 36771626, Free PMC Article
    5. Light-Induced Movements of Chloroplasts and Nuclei Are Regulated in Both Cp-Actin-Filament-Dependent and -Independent Manners in Arabidopsis thaliana. Suetsugu N, et al. PLoS One, 2016. PMID 27310016, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The results indicate that CHUP1 and KAC1/KAC2 function somewhat independently, but interdependently mediate both chloroplast and nuclear photorelocation movements in Arabidopsis cells.
      Title: Light-Induced Movements of Chloroplasts and Nuclei Are Regulated in Both Cp-Actin-Filament-Dependent and -Independent Manners in Arabidopsis thaliana.
    2. CHUP1 functions as a dimer and the leucine zippers in the N-terminal and C-terminal portion of the protein are involved in intramolecular interactions.
      Title: The functional domains of the chloroplast unusual positioning protein 1.
    3. After 5 minutes of exposure to blue light, there were significant differences in expression patterns in phot1 and phot2 mutants from that of the chup1 mutant.
      Title: Transitions of gene expression induced by short-term blue light.
    4. Under high light conditions, chup1 plants assumed significantly different guard cell chloroplast positions on both leaf surfaces than WT plants.
      Title: Light, genotype, and abscisic acid affect chloroplast positioning in guard cells of Arabidopsis thaliana leaves in distinct ways.
    5. CHUP1 localizes on the outer envelope of chloroplasts and anchors chloroplasts to the plasma membrane, forming a bridge to the actin cytoskeleton.
      Title: Chloroplast outer envelope protein CHUP1 is essential for chloroplast anchorage to the plasma membrane and chloroplast movement.
    6. Data show that CHUP1 as a linker between chloroplasts and the cytoskeleton, by interacting with actin and profilin.
      Title: The chloroplast outer membrane protein CHUP1 interacts with actin and profilin.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001203046.1
    NM_113468.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables actin filament binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables profilin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables signaling receptor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament polymerization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within chloroplast relocation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast outer membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Hydroxyproline-rich glycoprotein family protein
    NP_001189974.1
    • CHLOROPLAST UNUSUAL POSITIONING 1 (CHUP1); BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT4G18570.1).
    NP_001189975.1
    • CHLOROPLAST UNUSUAL POSITIONING 1 (CHUP1); BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT4G18570.1).
    NP_189197.2
    • CHLOROPLAST UNUSUAL POSITIONING 1 (CHUP1); INVOLVED IN: chloroplast relocation; LOCATED IN: chloroplast outer membrane, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT4G18570.1); Has 95745 Blast hits to 54491 proteins in 2679 species: Archae - 1109; Bacteria - 12651; Metazoa - 43667; Fungi - 7750; Plants - 7740; Viruses - 1623; Other Eukaryotes - 21205 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      9352444..9357953
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001338761.1 → NP_001327702.1  Hydroxyproline-rich glycoprotein family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A1I9LT47, Q9LI74
      UniProtKB/TrEMBL
      A0A178V7X6
      Conserved Domains (2) summary
      pfam10211
      Location:252 → 336
      Ax_dynein_light; Axonemal dynein light chain
      cl17182
      Location:80 → 230
      NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate

    2. NM_001338762.1 → NP_001327703.1  Hydroxyproline-rich glycoprotein family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V7X6, A0A1I9LT48

    3. NM_001338763.1 → NP_001327701.1  Hydroxyproline-rich glycoprotein family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A1I9LT47, Q9LI74
      UniProtKB/TrEMBL
      A0A178V7X6
      Conserved Domains (2) summary
      pfam10211
      Location:252 → 336
      Ax_dynein_light; Axonemal dynein light chain
      cl17182
      Location:80 → 230
      NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate

    4. NM_001203045.1 → NP_001189974.1  Hydroxyproline-rich glycoprotein family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189974.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A1I9LT47, Q9LI74
      UniProtKB/TrEMBL
      A0A178V7X6
      Conserved Domains (2) summary
      pfam10211
      Location:252 → 336
      Ax_dynein_light; Axonemal dynein light chain
      cl17182
      Location:80 → 230
      NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate

    5. NM_001203046.1 → NP_001189975.1  Hydroxyproline-rich glycoprotein family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189975.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V7X6, F4JA42
      Conserved Domains (2) summary
      pfam10211
      Location:111 → 195
      Ax_dynein_light; Axonemal dynein light chain
      pfam16046
      Location:22 → 150
      FAM76; FAM76 protein

    6. NM_113468.5 → NP_189197.2  Hydroxyproline-rich glycoprotein family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_189197.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A1I9LT47, Q9LI74
      UniProtKB/TrEMBL
      A0A178V7X6
      Conserved Domains (2) summary
      pfam10211
      Location:252 → 336
      Ax_dynein_light; Axonemal dynein light chain
      cl17182
      Location:80 → 230
      NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LI74.1

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