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    slc25a55a solute carrier family 25 member 55a [ Danio rerio (zebrafish) ]

    Gene ID: 406717, updated on 9-Dec-2024

    Summary

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    Official Symbol
    slc25a55aprovided by ZNC
    Official Full Name
    solute carrier family 25 member 55aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2745
    See related
    Ensembl:ENSDARG00000020893 AllianceGenome:ZFIN:ZDB-GENE-040426-2745
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb229; sb:cb229; slc25a22; zgc:56592; wu:fa12h05; wu:fb72h03
    Summary
    Predicted to enable L-aspartate transmembrane transporter activity and L-glutamate transmembrane transporter activity. Predicted to be involved in L-glutamate transmembrane transport; aspartate transmembrane transport; and malate-aspartate shuttle. Predicted to act upstream of or within transmembrane transport. Predicted to be located in mitochondrial inner membrane. Is expressed in several structures, including EVL; epidermis; mesoderm; nervous system; and periderm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See slc25a55a in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (49095642..49107046)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (49096972..49108394)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 5 member 8, like Neighboring gene thyroid stimulating hormone subunit beta a Neighboring gene tetraspanin 2a Neighboring gene uncharacterized LOC137496020 Neighboring gene nerve growth factor b (beta polypeptide)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Identification of WSB1 gene as an important regulator in the development of zebrafish embryo during midblastula transition. Lv W, et al. Acta Biochim Biophys Sin (Shanghai), 2008 Jun. PMID 18535746
    2. Uniform gene expression in embryos is achieved by temporal averaging of transcription noise. Stapel LC, et al. Genes Dev, 2017 Aug 15. PMID 28903980, Free PMC Article
    3. Targeted Gene Expression in Zebrafish Exposed to Chlorpyrifos-Oxon Confirms Phenotype-Specific Mechanisms Leading to Adverse Outcomes. Garcia-Reyero N, et al. Bull Environ Contam Toxicol, 2016 Jun. PMID 27086301, Free PMC Article
    4. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    5. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables L-aspartate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-glutamate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-glutamate transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-glutamate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in L-glutamate transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in aspartate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in malate-aspartate shuttle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    solute carrier family 25 member 55a
    Names
    solute carrier family 25 (mitochondrial carrier: glutamate), member 22

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213408.1 → NP_998573.1  solute carrier family 25 member 55a

      See identical proteins and their annotated locations for NP_998573.1

      Status: PROVISIONAL

      Source sequence(s)
      BC051620
      UniProtKB/TrEMBL
      A0A2R8RN92, Q6DI03, Q7ZTT6
      Related
      ENSDARP00000094162.3, ENSDART00000103385.4
      Conserved Domains (2) summary
      PTZ00169
      Location:1 → 292
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:3 → 97
      Mito_carr; Mitochondrial carrier protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      49095642..49107046
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005172109.4 → XP_005172166.1  solute carrier family 25 member 55a isoform X2

      See identical proteins and their annotated locations for XP_005172166.1

      UniProtKB/TrEMBL
      A0A8M2BJZ1
      Conserved Domains (1) summary
      pfam00153
      Location:123 → 205
      Mito_carr; Mitochondrial carrier protein

    2. XM_009302668.3 → XP_009300943.1  solute carrier family 25 member 55a isoform X2

      See identical proteins and their annotated locations for XP_009300943.1

      UniProtKB/TrEMBL
      A0A8M2BJZ1
      Conserved Domains (1) summary
      pfam00153
      Location:123 → 205
      Mito_carr; Mitochondrial carrier protein

    3. XM_017356461.2 → XP_017211950.1  solute carrier family 25 member 55a isoform X1

      UniProtKB/TrEMBL
      A0A2R8RN92, Q6DI03, Q7ZTT6
      Conserved Domains (2) summary
      PTZ00169
      Location:1 → 292
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:3 → 97
      Mito_carr; Mitochondrial carrier protein

    4. XM_005172105.5 → XP_005172162.1  solute carrier family 25 member 55a isoform X1

      See identical proteins and their annotated locations for XP_005172162.1

      UniProtKB/TrEMBL
      A0A2R8RN92, Q6DI03, Q7ZTT6
      Conserved Domains (2) summary
      PTZ00169
      Location:1 → 292
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:3 → 97
      Mito_carr; Mitochondrial carrier protein

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394668.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      197006..206449
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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