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    tulp4a TUB like protein 4a [ Danio rerio (zebrafish) ]

    Gene ID: 557730, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tulp4aprovided by ZNC
    Official Full Name
    TUB like protein 4aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060503-215
    See related
    Ensembl:ENSDARG00000045911 AllianceGenome:ZFIN:ZDB-GENE-060503-215
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    tulp4; fb99g11; wu:fb75h04; wu:fb99g11; si:ch211-51e12.5; si:ch211-222h17.4
    Summary
    Predicted to be involved in protein ubiquitination. Orthologous to human TULP4 (TUB like protein 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See tulp4a in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (331433..356196)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (317274..342748)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene si:ch211-51e12.7 Neighboring gene mitochondrial ribosomal protein S10 Neighboring gene transmembrane protein 181 Neighboring gene dynein light chain Tctex-type 1b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Wang D, et al. Proc Natl Acad Sci U S A, 2007 Jul 24. PMID 17640903, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tubby-related protein 4a
    Names
    tubby like protein 4
    tubby like protein 4a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045095.1 → NP_001038560.1  tubby-related protein 4a

      Status: PROVISIONAL

      Source sequence(s)
      BX890562
      UniProtKB/TrEMBL
      A0A8N7UYA6, E7EXF2
      Related
      ENSDARP00000067485.6, ENSDART00000067486.7
      Conserved Domains (4) summary
      COG2319
      Location:48 → 398
      WD40; WD40 repeat [General function prediction only]
      pfam01167
      Location:1562 → 1632
      Tub; Tub family
      sd00039
      Location:85 → 123
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:78 → 193
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      331433..356196
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005168512.5 → XP_005168569.1  tubby-related protein 4a isoform X1

      UniProtKB/TrEMBL
      A0A8M2BFT7, F6NJC6
      Related
      ENSDARP00000118167.2, ENSDART00000132625.4
      Conserved Domains (4) summary
      COG2319
      Location:48 → 398
      WD40; WD40 repeat [General function prediction only]
      pfam01167
      Location:1659 → 1729
      Tub; Tub family
      sd00039
      Location:85 → 123
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:78 → 193
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. XM_017355027.3 → XP_017210516.1  tubby-related protein 4a isoform X2

      UniProtKB/TrEMBL
      A0A8M6YZI4
      Conserved Domains (4) summary
      COG2319
      Location:48 → 398
      WD40; WD40 repeat [General function prediction only]
      pfam01167
      Location:1650 → 1720
      Tub; Tub family
      sd00039
      Location:85 → 123
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:78 → 193
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein Strain
    Heading Accession and Version

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