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    SERPINF2 serpin family F member 2 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 454412, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SERPINF2provided by VGNC
    Official Full Name
    serpin family F member 2provided by VGNC
    Primary source
    VGNC:VGNC:51732
    Locus tag
    CK820_G0046746
    See related
    Ensembl:ENSPTRG00000008536
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See SERPINF2 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 19 NC_072417.2 (12227100..12239541)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 17 NC_072415.1 (1676222..1688965, complement)

    Chromosome 19 - NC_072417.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC129137515 Neighboring gene microRNA mir-22 Neighboring gene WD repeat domain 81 Neighboring gene serpin family F member 1 Neighboring gene SET and MYND domain containing 4 Neighboring gene replication protein A1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of fibrinolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alpha-2-antiplasmin
    Names
    serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072417.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      12227100..12239541
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_016931152.4 → XP_016786641.1  alpha-2-antiplasmin isoform X1

      UniProtKB/TrEMBL
      A0A2I3TNI0, A0A2J8JKR7, A0A6D2WHS0, H2QBU4
      Related
      ENSPTRP00000090784.1
      Conserved Domains (1) summary
      cd02053
      Location:82 → 433
      alpha2AP; Alpha2-antiplasmin (alpha2AP) is the primary inhibitor of plasmin, a proteinase that digests fibrin, the main component of blood clots. Alpha2-Antiplasmin forms an inactive 1 : 1 stoichiometric complex with plasmin. It also rapidly crosslinks to fibrin ...

    2. XM_016931154.4 → XP_016786643.1  alpha-2-antiplasmin isoform X3

      UniProtKB/TrEMBL
      H2QBU4
      Conserved Domains (1) summary
      cd02053
      Location:86 → 437
      alpha2AP; Alpha2-antiplasmin (alpha2AP) is the primary inhibitor of plasmin, a proteinase that digests fibrin, the main component of blood clots. Alpha2-Antiplasmin forms an inactive 1 : 1 stoichiometric complex with plasmin. It also rapidly crosslinks to fibrin ...

    3. XM_016931153.4 → XP_016786642.1  alpha-2-antiplasmin isoform X2

      UniProtKB/TrEMBL
      H2QBU4
      Conserved Domains (1) summary
      cd02053
      Location:98 → 449
      alpha2AP; Alpha2-antiplasmin (alpha2AP) is the primary inhibitor of plasmin, a proteinase that digests fibrin, the main component of blood clots. Alpha2-Antiplasmin forms an inactive 1 : 1 stoichiometric complex with plasmin. It also rapidly crosslinks to fibrin ...
    Nucleotide Protein
    Heading Accession and Version

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