rhoh ras homolog family member H [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rhohprovided by ZNC
Official Full Name: ras homolog family member Hprovided by ZNC
Primary source: ZFIN:ZDB-GENE-060228-7
See related: Ensembl:ENSDARG00000070121 AllianceGenome:ZFIN:ZDB-GENE-060228-7
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in actin filament organization and signal transduction. Predicted to act upstream of or within small GTPase-mediated signal transduction. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in epidermodysplasia verruciformis. Orthologous to human RHOH (ras homolog family member H). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (23394263..23399661)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (22703524..22708922)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables GTP binding	IBA Inferred from Biological aspect of Ancestor more info
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables protein kinase binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in actin filament organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in signal transduction	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within small GTPase-mediated signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: rho-related GTP-binding protein RhoH

Names: ras homolog gene family, member H; ras-like protein Rhoh

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001327973.1 → NP_001314902.1 rho-related GTP-binding protein RhoH

Status: VALIDATED

Source sequence(s)

CR759875

UniProtKB/TrEMBL

A0A8M1P9P1, F1R1D2

Related

ENSDARP00000093421.3, ENSDART00000102646.4

Conserved Domains (2) summary

smart00174
Location:11 → 176

RHO; Rho (Ras homology) subfamily of Ras-like small GTPases

cd00157
Location:9 → 173

Rho; Ras homology family (Rho) of small guanosine triphosphatases (GTPases)