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    NIA2 nitrate reductase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 840630, updated on 18-Sep-2024

    Summary

    Official Symbol
    NIA2
    Official Full Name
    nitrate reductase 2
    Primary source
    TAIR:AT1G37130
    Locus tag
    AT1G37130
    See related
    Araport:AT1G37130
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS NITRATE REDUCTASE 2; ATNR2; B29; CHL3; CHLORATE RESISTANT 3; F28L22.2; F28L22_2; NIA2-1; NITRATE REDUCTASE; nitrate reductase 2; NITRATE REDUCTASE 2; NR; NR2
    Summary
    Identified as a mutant resistant to chlorate. Encodes nitrate reductase structural gene. Involved in nitrate assimilation. Has nitrate reductase activity. Up-regulated by the fungus P. indica. Binds transcription factor At2g35940.
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    Genomic context

    See NIA2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (14158452..14161938)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene MEI2 C-terminal RRM only like 1 Neighboring gene holocarboxylase synthetase 2

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_103364.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables FAD binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables molybdenum ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables molybdopterin cofactor binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nitrate reductase (NADH) activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables nitrate reductase (NADPH) activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nitrate reductase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables nitrate reductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    nitrate reductase 2
    NP_174901.1
    • nitrate reductase 2 (NIA2); FUNCTIONS IN: nitrate reductase activity, nitrate reductase (NADH) activity; INVOLVED IN: nitric oxide biosynthetic process, nitrate assimilation, response to light stimulus, response to symbiotic fungus; LOCATED IN: plasma membrane, vacuole; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Nitrate reductase NADH dependent (InterPro:IPR012137), Cytochrome b5, heme-binding site (InterPro:IPR018506), Ferredoxin reductase-type FAD-binding domain (InterPro:IPR017927), Oxidoreductase, FAD-binding domain (InterPro:IPR008333), Immunoglobulin E-set (InterPro:IPR014756), Cytochrome b5 (InterPro:IPR001199), NADH:cytochrome b5 reductase (CBR) (InterPro:IPR001834), Oxidoreductase, molybdopterin-binding domain (InterPro:IPR000572), Oxidoreductase FAD/NAD(P)-binding (InterPro:IPR001433), Oxidoreductase, molybdopterin binding site (InterPro:IPR022407), Riboflavin synthase-like beta-barrel (InterPro:IPR017938), Eukaryotic molybdopterin oxidoreductase (InterPro:IPR008335), Flavoprotein pyridine nucleotide cytochrome reductase (InterPro:IPR001709), Moybdenum cofactor oxidoreductase, dimerisation (InterPro:IPR005066); BEST Arabidopsis thaliana protein match is: nitrate reductase 1 (TAIR:AT1G77760.1); Has 14440 Blast hits to 14066 proteins in 2196 species: Archae - 142; Bacteria - 6584; Metazoa - 1752; Fungi - 2225; Plants - 1476; Viruses - 3; Other Eukaryotes - 2258 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      14158452..14161938
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_103364.3NP_174901.1  nitrate reductase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_174901.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P11035, Q7Y260
      UniProtKB/TrEMBL
      A0A178W376, A0A654EGF1, A0A7G2DVL3, Q0WLH2, Q0WUE2, Q94C76
      Conserved Domains (1) summary
      PLN02252
      Location:1917
      PLN02252; nitrate reductase [NADPH]