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    Mir132 microRNA 132 [ Mus musculus (house mouse) ]

    Gene ID: 387150, updated on 12-Nov-2024

    Summary

    Official Symbol
    Mir132provided by MGI
    Official Full Name
    microRNA 132provided by MGI
    Primary source
    MGI:MGI:2676817
    See related
    Ensembl:ENSMUSG00000065537 miRBase:MI0000158; AllianceGenome:MGI:2676817
    Gene type
    ncRNA
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mirn132; mir-132; mmu-mir-132
    Summary
    microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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    Genomic context

    See Mir132 in Genome Data Viewer
    Location:
    11 B5; 11 45.76 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (75064508..75064573)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (75173682..75173747)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene SMG6 nonsense mediated mRNA decay factor Neighboring gene RIKEN cDNA 1700016P03 gene Neighboring gene STARR-positive B cell enhancer ABC_E10686 Neighboring gene STARR-positive B cell enhancer ABC_E7016 Neighboring gene hypermethylated in cancer 1 Neighboring gene microRNA 212 Neighboring gene STARR-seq mESC enhancer starr_29983 Neighboring gene candidate tumor suppressor in ovarian cancer 2 Neighboring gene STARR-seq mESC enhancer starr_29985 Neighboring gene diphthamide biosynthesis 1 Neighboring gene reticulon 4 receptor-like 1 Neighboring gene STARR-seq mESC enhancer starr_29986 Neighboring gene predicted gene, 35169

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_029546.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      AL603905
      Related
      ENSMUST00000083603.4

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      75064508..75064573
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)