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    GA2 Terpenoid cyclases/Protein prenyltransferases superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 844284, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GA2
    Official Full Name
    Terpenoid cyclases/Protein prenyltransferases superfamily protein
    Primary source
    TAIR:AT1G79460
    Locus tag
    AT1G79460
    See related
    Araport:AT1G79460
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA ENT-KAURENE SYNTHASE; ARABIDOPSIS THALIANA ENT-KAURENE SYNTHASE 1; ATKS; ATKS1; ENT-KAURENE SYNTHASE; ENT-KAURENE SYNTHASE 1; GA REQUIRING 2; KS; KS1; T8K14.12; T8K14_12
    Summary
    Encodes for a protein with ent-kaurene synthase B activity which catalyzes the second step in the cyclization of GGPP to ent-kaurene in the gibberellins biosynthetic pathway.
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    Genomic context

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    See GA2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    15
    Sequence:
    Chromosome: 1; NC_003070.9 (29890367..29894646)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene aldehyde dehydrogenase 5F1 Neighboring gene ALA-interacting subunit 5 Neighboring gene Aldolase-type TIM barrel family protein Neighboring gene Carbohydrate-binding X8 domain superfamily protein Neighboring gene uncharacterized protein Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The GA2 locus of Arabidopsis thaliana encodes ent-kaurene synthase of gibberellin biosynthesis. Yamaguchi S, et al. Plant Physiol, 1998 Apr. PMID 9536043, Free PMC Article
    2. A maize (E)-beta-caryophyllene synthase implicated in indirect defense responses against herbivores is not expressed in most American maize varieties. Köllner TG, et al. Plant Cell, 2008 Feb. PMID 18296628, Free PMC Article
    3. A plastid envelope location of Arabidopsis ent-kaurene oxidase links the plastid and endoplasmic reticulum steps of the gibberellin biosynthesis pathway. Helliwell CA, et al. Plant J, 2001 Oct. PMID 11722763
    4. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_106594.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ent-kaurene synthase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within gibberellic acid mediated signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within gibberellin biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in gibberellin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within gibberellin biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in chloroplast stroma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plastid NAS
    Non-traceable Author Statement
    more info
    		  
    located_in plastid TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Terpenoid cyclases/Protein prenyltransferases superfamily protein
    NP_178064.1
    • GA REQUIRING 2 (GA2); FUNCTIONS IN: ent-kaurene synthase activity; INVOLVED IN: gibberellin biosynthetic process, gibberellic acid mediated signaling pathway; LOCATED IN: chloroplast stroma, chloroplast, plastid; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Terpene synthase, metal-binding domain (InterPro:IPR005630), Terpenoid synthase (InterPro:IPR008949), Terpenoid cylases/protein prenyltransferase alpha-alpha toroid (InterPro:IPR008930), Terpene synthase-like (InterPro:IPR001906); BEST Arabidopsis thaliana protein match is: terpene synthase 04 (TAIR:AT1G61120.1); Has 2032 Blast hits to 2016 proteins in 248 species: Archae - 0; Bacteria - 69; Metazoa - 0; Fungi - 62; Plants - 1897; Viruses - 0; Other Eukaryotes - 4 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      29890367..29894646
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106594.4 → NP_178064.1  Terpenoid cyclases/Protein prenyltransferases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178064.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O64952, Q67ZQ6, Q9SAK2
      UniProtKB/TrEMBL
      A0A178WDK0, A0A5S9WVS0
      Conserved Domains (1) summary
      PLN02279
      Location:1 → 785
      PLN02279; ent-kaur-16-ene synthase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SAK2.1

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