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    trpc3 transient receptor potential cation channel, subfamily C, member 3 [ Danio rerio (zebrafish) ]

    Gene ID: 101887082, updated on 4-Jan-2025

    Summary

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    Official Symbol
    trpc3provided by ZNC
    Official Full Name
    transient receptor potential cation channel, subfamily C, member 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-140129-1
    See related
    AllianceGenome:ZFIN:ZDB-GENE-140129-1
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable calcium channel activity. Predicted to act upstream of or within calcium ion transmembrane transport. Predicted to be located in membrane. Is expressed in nervous system. Human ortholog(s) of this gene implicated in cerebellar ataxia type 41. Orthologous to human TRPC3 (transient receptor potential cation channel subfamily C member 3). [provided by Alliance of Genome Resources, Jan 2025]
    Annotation information
    Annotation category: suggests misassembly
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See trpc3 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (3411621..3465892)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (3304305..3358586)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110440216 Neighboring gene im:7150988 Neighboring gene glutathione S-transferase pi 1.1 Neighboring gene glutathione S-transferase pi 1.2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Phylogeny and expression of canonical transient receptor potential (TRPC) genes in developing zebrafish. Von Niederhäusern V, et al. Dev Dyn, 2013 Dec. PMID 24038627
    2. Red LED light treatment promotes cognitive learning through up-regulation of trpm4 in zebrafish. You MS, et al. J Photochem Photobiol B, 2020 Dec. PMID 33186875
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    short transient receptor potential channel 3
    Names
    short transient receptor potential channel 3-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001289884.2 → NP_001276813.2  short transient receptor potential channel 3

      Status: VALIDATED

      Source sequence(s)
      CABZ01073823, CABZ01073825, FP102983, KF446630
      UniProtKB/TrEMBL
      A0A8M1P0G4, U3N8Z0
      Conserved Domains (4) summary
      cd00204
      Location:101 → 233
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      TIGR00870
      Location:78 → 869
      trp; transient-receptor-potential calcium channel protein
      pfam08344
      Location:247 → 306
      TRP_2; Transient receptor ion channel II
      sd00045
      Location:128 → 159
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      3411621..3465892
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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