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    SPRY4-AS1 SPRY4 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 101926941, updated on 10-Dec-2024

    Summary

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    Official Symbol
    SPRY4-AS1provided by HGNC
    Official Full Name
    SPRY4 antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:53465
    See related
    AllianceGenome:HGNC:53465
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    THCAT68; LINC01844
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See SPRY4-AS1 in Genome Data Viewer
    Location:
    5q31.3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (142325293..142464054)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (142855904..142995298)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (141704858..141843619)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107986455 Neighboring gene uncharacterized LOC124901096 Neighboring gene Sharpr-MPRA regulatory region 837 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:141560390-141560908 Neighboring gene MPRA-validated peak5506 silencer Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:141563869-141564765 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:141564766-141565661 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:141566635-141567164 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr5:141580673-141581872 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:141585270-141585770 Neighboring gene ReSE screen-validated silencer GRCh37_chr5:141595973-141596142 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23317 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:141612188-141612688 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:141616039-141616767 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:141625205-141625997 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:141625998-141626789 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:141659038-141659604 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:141659605-141660171 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:141690483-141690984 Neighboring gene NANOG hESC enhancer GRCh37_chr5:141699157-141699901 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:141702584-141703548 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:141703549-141704511 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:141711019-141711518 Neighboring gene SPRY4 intronic transcript 1 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr5:141721844-141723043 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:141734625-141735426 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:141735427-141736228 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16471 Neighboring gene ReSE screen-validated silencer GRCh37_chr5:141740409-141740647 Neighboring gene sprouty RTK signaling antagonist 4 Neighboring gene Sharpr-MPRA regulatory region 738 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:141743173-141743894 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23319 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:141768171-141768672 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:141771555-141772234 Neighboring gene Sharpr-MPRA regulatory region 12170 Neighboring gene Sharpr-MPRA regulatory region 9292 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:141854065-141854633 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr5:141854634-141855201 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:141855756-141856266 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:141902675-141903176 Neighboring gene VISTA enhancer hs1640 Neighboring gene ribosomal protein S12 pseudogene 10 Neighboring gene FGF1 promoter D Neighboring gene small nucleolar RNA SNORA36 family Neighboring gene fibroblast growth factor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Super-enhancer-associated long noncoding RNA AC005592.2 promotes tumor progression by regulating OLFM4 in colorectal cancer. Yan L, et al. BMC Cancer, 2021 Feb 23. PMID 33622275, Free PMC Article
    2. Identification of long non-coding RNAs that stimulate cell survival in bladder cancer. Dudek AM, et al. Oncotarget, 2017 May 23. PMID 28415801, Free PMC Article
    3. Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. Adams MD, et al. Nature, 1995 Sep 28. PMID 7566098
    4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Other Names

    • long intergenic non-protein coding RNA 1844

    Clone Names

    • AC005592.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_120664.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC010317, AC091825

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      142325293..142464054
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      142855904..142995298
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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