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    Gpr75 G protein-coupled receptor 75 [ Mus musculus (house mouse) ]

    Gene ID: 237716, updated on 9-Dec-2024

    Summary

    Official Symbol
    Gpr75provided by MGI
    Official Full Name
    G protein-coupled receptor 75provided by MGI
    Primary source
    MGI:MGI:2441843
    See related
    Ensembl:ENSMUSG00000043999 AllianceGenome:MGI:2441843
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Enables C-C chemokine receptor activity. Involved in chemokine-mediated signaling pathway. Predicted to be active in plasma membrane. Is expressed in several structures, including heart; liver; metanephros; skeletal muscle; and spleen. Orthologous to human GPR75 (G protein-coupled receptor 75). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in cerebellum adult (RPKM 2.1), frontal lobe adult (RPKM 1.6) and 8 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Gpr75 in Genome Data Viewer
    Location:
    11 A4; 11 18.16 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (30834636..30846090)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (30884633..30896090)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_29068 Neighboring gene predicted gene 12100 Neighboring gene STARR-seq mESC enhancer starr_29070 Neighboring gene proteasome (prosome, macropain) activator subunit 4 Neighboring gene spindle and kinetochore-associated protein 2 pseudogene Neighboring gene endoplasmic reticulum lectin 1 Neighboring gene PDZ and LIM domain protein 1 pseudogene Neighboring gene ankyrin repeat and SOCS box-containing 3 Neighboring gene ChaC, cation transport regulator 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (8)  1 citation
    • Targeted (1) 

    Pathways from PubChem

    General protein information

    Preferred Names
    probable G-protein coupled receptor 75

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175490.4NP_780699.2  probable G-protein coupled receptor 75

      See identical proteins and their annotated locations for NP_780699.2

      Status: VALIDATED

      Source sequence(s)
      AK141614, BQ175263
      Consensus CDS
      CCDS24508.1
      UniProtKB/Swiss-Prot
      Q3URC1, Q6X632, Q8BXP3
      UniProtKB/TrEMBL
      Q059L0
      Related
      ENSMUSP00000105057.2, ENSMUST00000109430.2
      Conserved Domains (1) summary
      cd15007
      Location:44387
      7tmA_GPR75; G protein-coupled receptor 75, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      30834636..30846090
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006514696.5XP_006514759.1  probable G-protein coupled receptor 75 isoform X1

      See identical proteins and their annotated locations for XP_006514759.1

      UniProtKB/Swiss-Prot
      Q3URC1, Q6X632, Q8BXP3
      UniProtKB/TrEMBL
      Q059L0
      Conserved Domains (1) summary
      cd15007
      Location:44387
      7tmA_GPR75; G protein-coupled receptor 75, member of the class A family of seven-transmembrane G protein-coupled receptors