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    Efcab3 EF-hand calcium binding domain 3 [ Mus musculus (house mouse) ]

    Gene ID: 70894, updated on 27-Nov-2024

    Summary

    Official Symbol
    Efcab3provided by MGI
    Official Full Name
    EF-hand calcium binding domain 3provided by MGI
    Primary source
    MGI:MGI:1918144
    See related
    Ensembl:ENSMUSG00000020690 AllianceGenome:MGI:1918144
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm19; Efcab13; Efcab15; Gm11639; 4921510J17Rik
    Summary
    Predicted to enable calcium ion binding activity. Orthologous to human EFCAB3 (EF-hand calcium binding domain 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 8.4) See more
    Orthologs
    NEW
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    Genomic context

    See Efcab3 in Genome Data Viewer
    Location:
    11 E1; 11
    Exon count:
    189
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (104576533..105008365)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (105008985..105117537)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr11:104469193-104469494 Neighboring gene STARR-positive B cell enhancer mm9_chr11:104483926-104484227 Neighboring gene STARR-positive B cell enhancer ABC_E1434 Neighboring gene integrin beta 3 Neighboring gene ribosomal protein L3 pseudogene Neighboring gene STARR-seq mESC enhancer starr_30895 Neighboring gene STARR-seq mESC enhancer starr_30896 Neighboring gene STARR-seq mESC enhancer starr_30897 Neighboring gene STARR-seq mESC enhancer starr_30898 Neighboring gene high mobility group box 2 pseudogene Neighboring gene STARR-seq mESC enhancer starr_30900 Neighboring gene STARR-seq mESC enhancer starr_30901 Neighboring gene predicted gene 11622 Neighboring gene microtubule-associated protein pseudogene Neighboring gene predicted gene, 25362 Neighboring gene STARR-positive B cell enhancer ABC_E7076 Neighboring gene methyltransferase 2, methylcytidine Neighboring gene predicted gene 11620

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (2)  1 citation

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    EF-hand calcium-binding domain-containing protein 3
    Names
    EF-hand calcium binding domain 13

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081046.2NP_001074515.1  EF-hand calcium-binding domain-containing protein 3 isoform 2

      See identical proteins and their annotated locations for NP_001074515.1

      Status: VALIDATED

      Source sequence(s)
      AL627235
      Consensus CDS
      CCDS36355.1
      UniProtKB/Swiss-Prot
      Q80X60
      Related
      ENSMUSP00000021029.6, ENSMUST00000021029.6
      Conserved Domains (2) summary
      PTZ00183
      Location:3116
      PTZ00183; centrin; Provisional
      pfam13833
      Location:62112
      EF-hand_8; EF-hand domain pair
    2. NM_001271338.1NP_001258267.1  EF-hand calcium-binding domain-containing protein 3 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL627235, AL645600, AL645725, AL645976, BX000996
      Related
      ENSMUSP00000148433.3, ENSMUST00000212287.3

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      104576533..105008365
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)