Dpm3 Dolichyl-phosphate mannosyltransferase subunit 3 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Dpm3provided by FlyBase
Official Full Name: Dolichyl-phosphate mannosyltransferase subunit 3provided by FlyBase
Primary source: FLYBASE:FBgn0053977
Locus tag: Dmel_CG33977
See related: AllianceGenome:FB:FBgn0053977
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG33977; Dmel\CG33977; DPM3
Summary: Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum. Predicted to be part of dolichol-phosphate-mannose synthase complex. Predicted to be active in endoplasmic reticulum membrane. Is expressed in adult head and adult heart. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type I and muscular dystrophy-dystroglycanopathy type B15. Orthologous to human DPM3 (dolichyl-phosphate mannosyltransferase subunit 3, regulatory). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (13402559..13403051, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (9228281..9228773, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Process	Evidence Code	Pubs
involved_in GPI anchor biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in GPI anchor biosynthetic process	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein glycosylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of dolichol-phosphate-mannose synthase complex	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum	ISS Inferred from Sequence or Structural Similarity more info
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info

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The following sections contain reference sequences that belong to a specific genome build. Explain