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    nmt1a N-myristoyltransferase 1a [ Danio rerio (zebrafish) ]

    Gene ID: 323956, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nmt1aprovided by ZNC
    Official Full Name
    N-myristoyltransferase 1aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050522-477
    See related
    Ensembl:ENSDARG00000052966 AllianceGenome:ZFIN:ZDB-GENE-050522-477
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    nmt1; nmt-1; im:2601337; wu:fc15d01; wu:fc18a04; zgc:110714
    Summary
    Predicted to enable glycylpeptide N-tetradecanoyltransferase activity. Predicted to be involved in protein localization to membrane. Predicted to act upstream of or within N-terminal protein myristoylation. Predicted to be located in cytoplasm and membrane. Predicted to be active in cytosol. Orthologous to human NMT1 (N-myristoyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See nmt1a in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (39238860..39259666, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (39097002..39117808, complement)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene CD209 antigen-like protein C Neighboring gene C-type lectin domain family 4 member E-like Neighboring gene phospholipase C, delta 3a Neighboring gene CLN3 lysosomal/endosomal transmembrane protein, battenin Neighboring gene Rho GTPase activating protein 23a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycylpeptide N-tetradecanoyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glycylpeptide N-tetradecanoyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within N-terminal protein myristoylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein localization to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    glycylpeptide N-tetradecanoyltransferase 1
    Names
    N-myristoyltransferase 1
    NP_001018316.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001020480.1 → NP_001018316.1  glycylpeptide N-tetradecanoyltransferase 1

      See identical proteins and their annotated locations for NP_001018316.1

      Status: PROVISIONAL

      Source sequence(s)
      BC095383
      UniProtKB/TrEMBL
      Q4VBR7
      Related
      ENSDARP00000105829.2, ENSDART00000124845.3
      Conserved Domains (3) summary
      COG5092
      Location:77 → 475
      NMT1; N-myristoyl transferase [Lipid metabolism]
      pfam01233
      Location:129 → 282
      NMT; Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain
      pfam02799
      Location:299 → 474
      NMT_C; Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      39238860..39259666 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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