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    denr density-regulated protein [ Danio rerio (zebrafish) ]

    Gene ID: 436970, updated on 9-Dec-2024

    Summary

    Official Symbol
    denrprovided by ZNC
    Official Full Name
    density-regulated proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-450
    See related
    Ensembl:ENSDARG00000037229 AllianceGenome:ZFIN:ZDB-GENE-040718-450
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:92629; im:6891640; zgc:113309
    Summary
    Predicted to enable translation initiation factor activity. Predicted to be involved in formation of translation preinitiation complex and translation reinitiation. Predicted to act upstream of or within translational initiation. Is expressed in midbrain; myotome; optic vesicle; and retina. Orthologous to human DENR (density regulated re-initiation and release factor). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: suggests misassembly
    Annotation category: partial on reference assembly
    Orthologs
    NEW
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    Genomic context

    See denr in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (44402825..44443349)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (44601282..44643202)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene lysine methyltransferase 5Aa Neighboring gene small nuclear ribonucleoprotein 35 (U11/U12) Neighboring gene CAP-GLY domain containing linker protein 1b Neighboring gene Rab interacting lysosomal protein-like 1 Neighboring gene CAP-Gly domain-containing linker protein 1 Neighboring gene hydroxycarboxylic acid receptor 1-2 Neighboring gene hydroxycarboxylic acid receptor 1-1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in formation of translation preinitiation complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in translation reinitiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within translational initiation IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    density-regulated protein
    Names
    DRP

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002697.2NP_001002697.1  density-regulated protein

      See identical proteins and their annotated locations for NP_001002697.1

      Status: PROVISIONAL

      Source sequence(s)
      BC095896
      UniProtKB/Swiss-Prot
      Q6DH65
      Related
      ENSDARP00000149057.1, ENSDART00000181517.1
      Conserved Domains (1) summary
      cl00229
      Location:26203
      eIF1_SUI1_like; Eukaryotic initiation factor 1 and related proteins

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      44402825..44443349
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)