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    Tspan11 tetraspanin 11 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 312727, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tspan11provided by RGD
    Official Full Name
    tetraspanin 11provided by RGD
    Primary source
    RGD:1305424
    See related
    EnsemblRapid:ENSRNOG00000054360 AllianceGenome:RGD:1305424
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305424
    Summary
    Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human TSPAN11 (tetraspanin 11). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 46.5), Uterus (RPKM 35.4) and 7 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tspan11 in Genome Data Viewer
    Location:
    4q42
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (162424327..162491653)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (160738149..160805522)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (160455845..160522905)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102548836 Neighboring gene uncharacterized LOC134486641 Neighboring gene uncharacterized LOC134486845 Neighboring gene tetraspanin 9 Neighboring gene RIKEN cDNA 4930433N12 gene like Neighboring gene Sumo1/sentrin/SMT3 specific peptidase 18

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC109445

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    tetraspanin-11
    Names
    tspan-11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024262.1 → NP_001019433.1  tetraspanin-11

      See identical proteins and their annotated locations for NP_001019433.1

      Status: PROVISIONAL

      Source sequence(s)
      BC092652
      UniProtKB/Swiss-Prot
      Q568Y5
      UniProtKB/TrEMBL
      A6ILY9
      Related
      ENSRNOP00000074465.1, ENSRNOT00000087834.3
      Conserved Domains (2) summary
      cd03155
      Location:112 → 220
      CD151_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD151_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
      pfam00335
      Location:16 → 248
      Tetraspannin; Tetraspanin family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      162424327..162491653
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008763291.4 → XP_008761513.1  tetraspanin-11 isoform X2

      Conserved Domains (2) summary
      cl02781
      Location:112 → 152
      tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
      pfam00335
      Location:16 → 152
      Tetraspannin; Tetraspanin family

    2. XM_039107687.2 → XP_038963615.1  tetraspanin-11 isoform X3

      Conserved Domains (1) summary
      cd03155
      Location:48 → 156
      CD151_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD151_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...

    3. XM_039107685.2 → XP_038963613.1  tetraspanin-11 isoform X1

      UniProtKB/TrEMBL
      A0A8I6G2Z3
      Related
      ENSRNOP00000078487.1, ENSRNOT00000103340.2
      Conserved Domains (1) summary
      cd03155
      Location:91 → 195
      CD151_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD151_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...

    4. XM_039107688.2 → XP_038963616.1  tetraspanin-11 isoform X4

      Conserved Domains (1) summary
      cd03155
      Location:28 → 136
      CD151_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD151_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q568Y5.1 GenPept UniProtKB/Swiss-Prot:Q568Y5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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