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    Mea1 male-enhanced antigen 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 685131, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mea1provided by RGD
    Official Full Name
    male-enhanced antigen 1provided by RGD
    Primary source
    RGD:1597751
    See related
    EnsemblRapid:ENSRNOG00000017144 AllianceGenome:RGD:1597751
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in cell differentiation and spermatogenesis. Predicted to be located in cytoplasm. Orthologous to human MEA1 (male-enhanced antigen 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 677.6), Muscle (RPKM 396.2) and 9 other tissues See more
    Orthologs
    human mouse all
    NEW
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    Genomic context

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    See Mea1 in Genome Data Viewer
    Location:
    9q12
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (21797884..21801693, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (14300283..14304130, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (16610312..16614153, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene canopy FGF signaling regulator 3 Neighboring gene glycine N-methyltransferase Neighboring gene peroxisomal biogenesis factor 6 Neighboring gene protein phosphatase 2, regulatory subunit B', delta Neighboring gene kelch domain containing 3 Neighboring gene ribosomal RNA processing 36 Neighboring gene cullin 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Male-enhanced antigen-1 gene flanked by two overlapping genes is expressed in late spermatogenesis. Ohinata Y, et al. Biol Reprod, 2002 Dec. PMID 12444059
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC109389

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    male-enhanced antigen 1
    Names
    MEA-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044286.1 → NP_001037751.1  male-enhanced antigen 1

      See identical proteins and their annotated locations for NP_001037751.1

      Status: PROVISIONAL

      Source sequence(s)
      BC089978
      UniProtKB/Swiss-Prot
      Q5FVH7
      UniProtKB/TrEMBL
      A0A0G2JV28
      Related
      ENSRNOP00000023495.2, ENSRNOT00000023495.6
      Conserved Domains (1) summary
      pfam06910
      Location:54 → 170
      MEA1; Male enhanced antigen 1 (MEA1)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      21797884..21801693 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008766880.3 → XP_008765102.1  male-enhanced antigen 1 isoform X1

      See identical proteins and their annotated locations for XP_008765102.1

      UniProtKB/Swiss-Prot
      Q5FVH7
      UniProtKB/TrEMBL
      A0A0G2JV28
      Conserved Domains (1) summary
      pfam06910
      Location:54 → 170
      MEA1; Male enhanced antigen 1 (MEA1)

    2. XM_006244569.5 → XP_006244631.1  male-enhanced antigen 1 isoform X1

      See identical proteins and their annotated locations for XP_006244631.1

      UniProtKB/Swiss-Prot
      Q5FVH7
      UniProtKB/TrEMBL
      A0A0G2JV28
      Conserved Domains (1) summary
      pfam06910
      Location:54 → 170
      MEA1; Male enhanced antigen 1 (MEA1)

    3. XM_006244567.5 → XP_006244629.1  male-enhanced antigen 1 isoform X1

      See identical proteins and their annotated locations for XP_006244629.1

      UniProtKB/Swiss-Prot
      Q5FVH7
      UniProtKB/TrEMBL
      A0A0G2JV28
      Conserved Domains (1) summary
      pfam06910
      Location:54 → 170
      MEA1; Male enhanced antigen 1 (MEA1)

    4. XM_006244568.5 → XP_006244630.1  male-enhanced antigen 1 isoform X1

      See identical proteins and their annotated locations for XP_006244630.1

      UniProtKB/Swiss-Prot
      Q5FVH7
      UniProtKB/TrEMBL
      A0A0G2JV28
      Conserved Domains (1) summary
      pfam06910
      Location:54 → 170
      MEA1; Male enhanced antigen 1 (MEA1)

    5. XM_039084216.2 → XP_038940144.1  male-enhanced antigen 1 isoform X1

      UniProtKB/Swiss-Prot
      Q5FVH7
      UniProtKB/TrEMBL
      A0A0G2JV28
      Conserved Domains (1) summary
      pfam06910
      Location:54 → 170
      MEA1; Male enhanced antigen 1 (MEA1)

    6. XM_039084215.2 → XP_038940143.1  male-enhanced antigen 1 isoform X1

      UniProtKB/Swiss-Prot
      Q5FVH7
      UniProtKB/TrEMBL
      A0A0G2JV28
      Conserved Domains (1) summary
      pfam06910
      Location:54 → 170
      MEA1; Male enhanced antigen 1 (MEA1)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5FVH7.1 GenPept UniProtKB/Swiss-Prot:Q5FVH7

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