U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Nucleotide

    • Showing Current items.

    ptprz1a protein tyrosine phosphatase receptor type Z1a [ Danio rerio (zebrafish) ]

    Gene ID: 497461, updated on 4-Jan-2025

    Summary

    Official Symbol
    ptprz1aprovided by ZNC
    Official Full Name
    protein tyrosine phosphatase receptor type Z1aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090406-1
    See related
    Ensembl:ENSDARG00000051814 AllianceGenome:ZFIN:ZDB-GENE-090406-1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ca16c; ptprz1; ptprza; zCA16c; im:7144789
    Summary
    Predicted to enable protein tyrosine phosphatase activity. Predicted to act upstream of or within protein dephosphorylation. Predicted to be located in membrane. Orthologous to human PTPRZ1 (protein tyrosine phosphatase receptor type Z1). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ptprz1a in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (28340171..28497494, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (27897053..28054384, complement)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene FEZ family zinc finger 1 Neighboring gene aminoadipate-semialdehyde synthase Neighboring gene solute carrier family 15 member 5 Neighboring gene PKc_like domain-containing protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphoprotein phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    carbonic anhydrase XVI c; receptor-type tyrosine-protein phosphatase zeta
    Names
    protein tyrosine phosphatase zeta A
    protein tyrosine phosphatase, receptor-type, Z polypeptide 1a
    XP_002666925.3
    XP_005163194.1
    XP_009296374.1
    XP_021326376.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      28340171..28497494 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021470701.2XP_021326376.1  receptor-type tyrosine-protein phosphatase zeta isoform X4

      UniProtKB/TrEMBL
      A0A8M9PVK4
      Conserved Domains (3) summary
      smart00194
      Location:517792
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd03122
      Location:48301
      alpha_CARP_receptor_like; Carbonic anhydrase alpha related protein, receptor_like subfamily. Carbonic anhydrase related proteins (CARPs) are sequence similar to carbonic anhydrases. Carbonic anhydrases are zinc-containing enzymes that catalyze the reversible hydration of carbon ...
      pfam00041
      Location:316398
      fn3; Fibronectin type III domain
    2. XM_009298099.4XP_009296374.1  receptor-type tyrosine-protein phosphatase zeta isoform X3

      UniProtKB/TrEMBL
      A0A8M3B7A9
      Conserved Domains (4) summary
      smart00194
      Location:7461021
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:7821021
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd03122
      Location:48301
      alpha_CARP_receptor_like; Carbonic anhydrase alpha related protein, receptor_like subfamily. Carbonic anhydrase related proteins (CARPs) are sequence similar to carbonic anhydrases. Carbonic anhydrases are zinc-containing enzymes that catalyze the reversible hydration of carbon ...
      pfam00041
      Location:316398
      fn3; Fibronectin type III domain
    3. XM_002666879.7XP_002666925.3  receptor-type tyrosine-protein phosphatase zeta isoform X2

      UniProtKB/TrEMBL
      A0A8M1RL98
      Conserved Domains (4) summary
      smart00194
      Location:12251493
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:12541493
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd03122
      Location:48301
      alpha_CARP_receptor_like; Carbonic anhydrase alpha related protein, receptor_like subfamily. Carbonic anhydrase related proteins (CARPs) are sequence similar to carbonic anhydrases. Carbonic anhydrases are zinc-containing enzymes that catalyze the reversible hydration of carbon ...
      pfam00041
      Location:316398
      fn3; Fibronectin type III domain
    4. XM_005163137.5XP_005163194.1  receptor-type tyrosine-protein phosphatase zeta isoform X1

      UniProtKB/TrEMBL
      A0A8M2BAH5
      Related
      ENSDARP00000128733.1, ENSDART00000157243.3
      Conserved Domains (4) summary
      smart00194
      Location:12251500
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:12611500
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd03122
      Location:48301
      alpha_CARP_receptor_like; Carbonic anhydrase alpha related protein, receptor_like subfamily. Carbonic anhydrase related proteins (CARPs) are sequence similar to carbonic anhydrases. Carbonic anhydrases are zinc-containing enzymes that catalyze the reversible hydration of carbon ...
      pfam00041
      Location:316398
      fn3; Fibronectin type III domain