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    Rpl31 ribosomal protein L31 [ Mus musculus (house mouse) ]

    Gene ID: 114641, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rpl31provided by MGI
    Official Full Name
    ribosomal protein L31provided by MGI
    Primary source
    MGI:MGI:2149632
    See related
    Ensembl:ENSMUSG00000073702 AllianceGenome:MGI:2149632
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Dts
    Summary
    A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in early conceptus and embryo. Orthologous to human RPL31 (ribosomal protein L31). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in liver E14 (RPKM 213.5), bladder adult (RPKM 185.2) and 24 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Rpl31 in Genome Data Viewer
    Location:
    1 B; 1 18.3 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (39406987..39410992)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (39367851..39371911)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene neuronal PAS domain protein 2 Neighboring gene ribosomal protein L17 pseudogene Neighboring gene STARR-seq mESC enhancer starr_00710 Neighboring gene predicted gene, 53549 Neighboring gene TBC1 domain family, member 8 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:39535681-39535790 Neighboring gene STARR-seq mESC enhancer starr_00719 Neighboring gene STARR-seq mESC enhancer starr_00720 Neighboring gene STARR-seq mESC enhancer starr_00721 Neighboring gene STARR-positive B cell enhancer ABC_E7719 Neighboring gene STARR-positive B cell enhancer ABC_E3270 Neighboring gene predicted gene, 24826 Neighboring gene predicted gene, 53550 Neighboring gene CCR4-NOT transcription complex, subunit 11

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. ERO1-L, a human protein that favors disulfide bond formation in the endoplasmic reticulum. Cabibbo A, et al. J Biol Chem, 2000 Feb 18. PMID 10671517
    2. Identification of Viral and Host Proteins That Interact with Murine Gammaherpesvirus 68 Latency-Associated Nuclear Antigen during Lytic Replication: a Role for Hsc70 in Viral Replication. Salinas E, et al. J Virol, 2016 Feb 1. PMID 26581985, Free PMC Article
    3. Transcription profile during maternal to zygotic transition in the mouse embryo. Li XY, et al. Reprod Fertil Dev, 2006. PMID 16930510
    4. CHIP as a membrane-shuttling proteostasis sensor. Kopp Y, et al. Elife, 2017 Nov 1. PMID 29091030, Free PMC Article
    5. Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders. Fairfield H, et al. Genome Res, 2015 Jul. PMID 25917818, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Spontaneous (2) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC106651, MGC107628

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cytoplasmic translation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic large ribosomal subunit IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of cytosolic large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in postsynapse NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in ribosome NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in synapse EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    large ribosomal subunit protein eL31
    Names
    60S ribosomal protein L31

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001252218.2 → NP_001239147.1  large ribosomal subunit protein eL31

      See identical proteins and their annotated locations for NP_001239147.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1-3 encode the same protein.
      Source sequence(s)
      AC132571
      Consensus CDS
      CCDS14904.1
      UniProtKB/Swiss-Prot
      P62900
      UniProtKB/TrEMBL
      Q5M9K9, Q9CY93
      Related
      ENSMUSP00000137631.2, ENSMUST00000179954.8
      Conserved Domains (1) summary
      pfam01198
      Location:19 → 100
      Ribosomal_L31e; Ribosomal protein L31e

    2. NM_001252219.2 → NP_001239148.1  large ribosomal subunit protein eL31

      See identical proteins and their annotated locations for NP_001239148.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1-3 encode the same protein.
      Source sequence(s)
      AC132571
      Consensus CDS
      CCDS14904.1
      UniProtKB/Swiss-Prot
      P62900
      UniProtKB/TrEMBL
      Q5M9K9, Q9CY93
      Related
      ENSMUSP00000136354.2, ENSMUST00000178079.8
      Conserved Domains (1) summary
      pfam01198
      Location:19 → 100
      Ribosomal_L31e; Ribosomal protein L31e

    3. NM_053257.4 → NP_444487.1  large ribosomal subunit protein eL31

      See identical proteins and their annotated locations for NP_444487.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1-3 encode the same protein.
      Source sequence(s)
      AC132571
      Consensus CDS
      CCDS14904.1
      UniProtKB/Swiss-Prot
      P62900
      UniProtKB/TrEMBL
      Q5M9K9, Q9CY93
      Related
      ENSMUSP00000083722.7, ENSMUST00000086535.12
      Conserved Domains (1) summary
      pfam01198
      Location:19 → 100
      Ribosomal_L31e; Ribosomal protein L31e

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      39406987..39410992
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P62900.1 GenPept UniProtKB/Swiss-Prot:P62900

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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