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    sccpdha.1 saccharopine dehydrogenase a, tandem duplicate 1 [ Danio rerio (zebrafish) ]

    Gene ID: 436632, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sccpdha.1provided by ZNC
    Official Full Name
    saccharopine dehydrogenase a, tandem duplicate 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-51
    See related
    Ensembl:ENSDARG00000075766 AllianceGenome:ZFIN:ZDB-GENE-040718-51
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb63c02; sccpdha; zgc:92525; wu:fb63c02
    Summary
    Predicted to be involved in glycolipid biosynthetic process. Predicted to be active in lipid droplet. Orthologous to human SCCPDH (saccharopine dehydrogenase (putative)). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See sccpdha.1 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (12159567..12175772)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (12005501..12021706)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene consortin, connexin sorting protein a Neighboring gene saccharopine dehydrogenase a, tandem duplicate 2 Neighboring gene kinesin family member 28 Neighboring gene AT hook containing transcription factor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Srag Regulates Autophagy via Integrating into a Preexisting Autophagy Pathway in Testis. Cheng Y, et al. Mol Biol Evol, 2021 Jan 4. PMID 32722765, Free PMC Article
    2. Comparative analysis of the testis and ovary transcriptomes in zebrafish by combining experimental and computational tools. Li Y, et al. Comp Funct Genomics, 2004. PMID 18629171, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in glycolipid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in lipid droplet IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    saccharopine dehydrogenase a, tandem duplicate 1
    Names
    sccpdh

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002359.1 → NP_001002359.1  saccharopine dehydrogenase a, tandem duplicate 1

      See identical proteins and their annotated locations for NP_001002359.1

      Status: PROVISIONAL

      Source sequence(s)
      BC076056
      UniProtKB/TrEMBL
      A0A8M1N0D7, A9JT27, Q6DHB9
      Related
      ENSDARP00000046801.5, ENSDART00000046802.7
      Conserved Domains (2) summary
      COG3268
      Location:10 → 424
      COG3268; Uncharacterized conserved protein, related to short-chain dehydrogenases [Function unknown]
      pfam03435
      Location:14 → 152
      Sacchrp_dh_NADP; Saccharopine dehydrogenase NADP binding domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      12159567..12175772
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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