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    CG11309 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40356, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG11309provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037070
    Locus tag
    Dmel_CG11309
    See related
    AllianceGenome:FB:FBgn0037070
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG11309
    Summary
    Enables serine hydrolase activity. Is expressed in adult head. Orthologous to several human genes including SERHL2 (serine hydrolase like 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11309 in Genome Data Viewer
    Location:
    78C6-78C6; 3-47 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (21301785..21304658, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (21294885..21297758, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45432 Neighboring gene Cuticular protein 78Cc Neighboring gene antisense RNA:CR45952 Neighboring gene uncharacterized protein Neighboring gene Polycomb Neighboring gene long non-coding RNA:CR45674

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila polypyrimidine tract-binding protein (DmPTB) regulates dorso-ventral patterning genes in embryos. Heimiller J, et al. PLoS One, 2014. PMID 25014769, Free PMC Article
    2. Genome-Wide Association Analyses Point to Candidate Genes for Electric Shock Avoidance in Drosophila melanogaster. Appel M, et al. PLoS One, 2015. PMID 25992709, Free PMC Article
    3. A Superfamily-wide Activity Atlas of Serine Hydrolases in Drosophila melanogaster. Kumar K, et al. Biochemistry, 2021 Apr 27. PMID 33827210, Free PMC Article
    4. Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution. Leung W, et al. G3 (Bethesda), 2015 Mar 4. PMID 25740935, Free PMC Article
    5. Comprehensive Identification and Alternative Splicing of Microexons in Drosophila. Pang TL, et al. Front Genet, 2021. PMID 33859668, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine hydrolase activity HDA PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11309-PA
    CG11309-PB
    CG11309-PC
    CG11309-PD
    CG11309-PE
    CG11309-PF
    NP_001262147.1
    NP_001262148.1
    NP_001262149.1
    NP_001287141.1
    NP_649301.1
    NP_730617.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      21301785..21304658 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300212.1 → NP_001287141.1  uncharacterized protein Dmel_CG11309, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287141.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VP52
      Conserved Domains (2) summary
      pfam00561
      Location:59 → 314
      Abhydrolase_1; alpha/beta hydrolase fold
      pfam12695
      Location:63 → 148
      Abhydrolase_5; Alpha/beta hydrolase family

    2. NM_001275219.1 → NP_001262148.1  uncharacterized protein Dmel_CG11309, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262148.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VP52
      Conserved Domains (2) summary
      pfam00561
      Location:59 → 314
      Abhydrolase_1; alpha/beta hydrolase fold
      pfam12695
      Location:63 → 148
      Abhydrolase_5; Alpha/beta hydrolase family

    3. NM_141044.4 → NP_649301.1  uncharacterized protein Dmel_CG11309, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649301.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VP51
      Related
      FBpp0078061
      Conserved Domains (2) summary
      COG0596
      Location:68 → 337
      MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
      pfam12695
      Location:73 → 158
      Abhydrolase_5; Alpha/beta hydrolase family

    4. NM_001275218.1 → NP_001262147.1  uncharacterized protein Dmel_CG11309, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262147.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VP52
      Conserved Domains (2) summary
      pfam00561
      Location:59 → 314
      Abhydrolase_1; alpha/beta hydrolase fold
      pfam12695
      Location:63 → 148
      Abhydrolase_5; Alpha/beta hydrolase family

    5. NM_168896.3 → NP_730617.1  uncharacterized protein Dmel_CG11309, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730617.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VP52
      Related
      FBpp0078060
      Conserved Domains (2) summary
      pfam00561
      Location:59 → 314
      Abhydrolase_1; alpha/beta hydrolase fold
      pfam12695
      Location:63 → 148
      Abhydrolase_5; Alpha/beta hydrolase family

    6. NM_001275220.1 → NP_001262149.1  uncharacterized protein Dmel_CG11309, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262149.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VP52
      Conserved Domains (2) summary
      pfam00561
      Location:59 → 314
      Abhydrolase_1; alpha/beta hydrolase fold
      pfam12695
      Location:63 → 148
      Abhydrolase_5; Alpha/beta hydrolase family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VP51 Q9VP51
    Q9VP52 Q9VP52

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