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    TpnC73F Troponin C at 73F [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39916, updated on 17-Dec-2024

    Summary

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    Official Symbol
    TpnC73Fprovided by FlyBase
    Official Full Name
    Troponin C at 73Fprovided by FlyBase
    Primary source
    FLYBASE:FBgn0010424
    Locus tag
    Dmel_CG7930
    See related
    AllianceGenome:FB:FBgn0010424
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG7930; Dmel\CG7930; DmTnC3; DmTpnC73F; DmTpnCIa; TnC; TNC; Tnc2; TnC73F; TNC73F; TpnC Ia; tpnC73F; TpnCIa
    Summary
    Predicted to enable calcium ion binding activity and enzyme regulator activity. Predicted to be involved in microtubule cytoskeleton organization. Predicted to be active in cytoplasm. Is expressed in several structures, including adult heart; border follicle cell; larval muscle system; larval somatic muscle cell; and somatic muscle primordium. Orthologous to human CALML6 (calmodulin like 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See TpnC73F in Genome Data Viewer
    Location:
    73E5-73E5; 3-45 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17046063..17048390)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17039163..17041490)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene bad egg Neighboring gene SR-related CTD associated factor 6 Neighboring gene PAPS transporter 2 Neighboring gene POP5 ribonuclease P/MRP subunit Neighboring gene rogdi Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila melanogaster genes encoding three troponin-C isoforms and a calmodulin-related protein. Fyrberg C, et al. Biochem Genet, 1994 Apr. PMID 7980384
    2. Expression patterns of the whole troponin C gene repertoire during Drosophila development. Herranz R, et al. Gene Expr Patterns, 2004 Mar. PMID 15161098
    3. Troponin C in different insect muscle types: identification of two isoforms in Lethocerus, Drosophila and Anopheles that are specific to asynchronous flight muscle in the adult insect. Qiu F, et al. Biochem J, 2003 May 1. PMID 12558500, Free PMC Article
    4. Spatial and temporal requirement of Mlp60A isoforms during muscle development and function in Drosophila melanogaster. Wishard R, et al. Exp Cell Res, 2023 Jan 1. PMID 36423661
    5. Phylogenetic relationship of muscle tissues deduced from superimposition of gene trees. OOta S, et al. Mol Biol Evol, 1999 Jun. PMID 10368962

    See all (57) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    troponin C at 73F
    Names
    CG7930-PA
    CG7930-PC
    TpnC73F-PA
    TpnC73F-PC
    TroponinC73F
    troponin C
    troponin C73F

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      17046063..17048390
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300162.1 → NP_001287091.1  troponin C at 73F, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287091.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C8VV65, P47949, Q9VVE1
      UniProtKB/TrEMBL
      X2JCI6
      Conserved Domains (1) summary
      PTZ00184
      Location:6 → 153
      PTZ00184; calmodulin; Provisional

    2. NM_079398.4 → NP_524122.2  troponin C at 73F, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524122.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C8VV65, P47949, Q9VVE1
      UniProtKB/TrEMBL
      X2JCI6
      Related
      FBpp0088546
      Conserved Domains (1) summary
      PTZ00184
      Location:6 → 153
      PTZ00184; calmodulin; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P47949.2 P47949
    Q8MS39 Q8MS39
    X2JCI6 X2JCI6

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