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    CG11583 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 326206, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG11583provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035524
    Locus tag
    Dmel_CG11583
    See related
    AllianceGenome:FB:FBgn0035524
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG32253; dBRX1; Dmel\CG11583
    Summary
    Predicted to enable rRNA binding activity. Predicted to be involved in ribosomal large subunit assembly. Predicted to be active in nucleolus. Is expressed in several structures, including Malpighian tubule primordium; adult head; embryonic/larval midgut primordium; larval muscle cell; and visceral mesoderm derivative. Orthologous to human BRIX1 (biogenesis of ribosomes BRX1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11583 in Genome Data Viewer
    Location:
    64A12-64A12; 3-10 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4281504..4282817, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4281504..4282817, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Vacuolar H[+] ATPase M9.7 subunit a Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Choline transporter-like 1 Neighboring gene uncharacterized protein Neighboring gene shrew

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The archaeal homolog of the Imp4 protein, a eukaryotic U3 snoRNP component. Mayer C, et al. Trends Biochem Sci, 2001 Mar. PMID 11246005
    2. Heterogeneous receptor expression underlies non-uniform peptidergic modulation of olfaction in Drosophila. Sizemore TR, et al. Nat Commun, 2023 Aug 30. PMID 37644052, Free PMC Article
    3. p53- and ERK7-dependent ribosome surveillance response regulates Drosophila insulin-like peptide secretion. Hasygar K, et al. PLoS Genet, 2014 Nov. PMID 25393288, Free PMC Article
    4. Leishmania amazonensis sabotages host cell SUMOylation for intracellular survival. Okuda K, et al. iScience, 2022 Sep 16. PMID 36060064, Free PMC Article
    5. The pentameric nucleoplasmin fold is present in Drosophila FKBP39 and a large number of chromatin-related proteins. Edlich-Muth C, et al. J Mol Biol, 2015 May 22. PMID 25813344, Free PMC Article

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables rRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ribosomal large subunit assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11583-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      4281504..4282817 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001038900.2 → NP_001033989.1  uncharacterized protein Dmel_CG11583 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001033989.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8MSC3, Q9VZE6
      Conserved Domains (1) summary
      cl00935
      Location:43 → 290
      Brix; Brix domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VZE6.2 Q9VZE6

    Gene LinkOut

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