Shawl Shaw-like [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Shawlprovided by FlyBase
Official Full Name: Shaw-likeprovided by FlyBase
Primary source: FLYBASE:FBgn0085395
Locus tag: Dmel_CG34366
See related: AllianceGenome:FB:FBgn0085395
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG13111; CG34366; CG4450; Dmel\CG34366; Kv3; Kv3.2; shawl
Old locus tag: CG13111; CG4450; Dmel_CG13111; Dmel_CG4450
Summary: Predicted to enable delayed rectifier potassium channel activity. Predicted to be involved in action potential and potassium ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in several cellular components, including dendrite membrane; neuronal cell body membrane; and synaptic membrane. Is expressed in adult head. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 103. Orthologous to human KCNC2 (potassium voltage-gated channel subfamily C member 2) and KCNC4 (potassium voltage-gated channel subfamily C member 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (9370309..9415156, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (9370309..9415156, complement)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

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Function	Evidence Code	Pubs
enables delayed rectifier potassium channel activity	IBA Inferred from Biological aspect of Ancestor more info
enables voltage-gated monoatomic cation channel activity	ISS Inferred from Sequence or Structural Similarity more info
enables voltage-gated potassium channel activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in action potential	IBA Inferred from Biological aspect of Ancestor more info
involved_in potassium ion transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in potassium ion transport	IEA Inferred from Electronic Annotation more info
involved_in potassium ion transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein homooligomerization	IEA Inferred from Electronic Annotation more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in axon terminus	IBA Inferred from Biological aspect of Ancestor more info
is_active_in dendrite membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in neuronal cell body membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in postsynaptic membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in presynaptic membrane	IBA Inferred from Biological aspect of Ancestor more info
part_of voltage-gated potassium channel complex	IBA Inferred from Biological aspect of Ancestor more info
part_of voltage-gated potassium channel complex	IEA Inferred from Electronic Annotation more info
part_of voltage-gated potassium channel complex	ISS Inferred from Sequence or Structural Similarity more info

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