U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Nucleotide

    • Showing Current items.

    janA janus A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43569, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    janAprovided by FlyBase
    Official Full Name
    janus Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0001280
    Locus tag
    Dmel_CG7933
    See related
    AllianceGenome:FB:FBgn0001280
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:AT12574; CG7933; Dmel\CG7933; jan; Jan; jan A; janus; Y
    Summary
    Predicted to enable protein histidine phosphatase activity. Involved in sex differentiation. Predicted to be active in cytosol. Is expressed in several structures, including embryonic/larval midgut primordium; female germline cell; gonad; gut section; and sensory nervous system primordium. Orthologous to human PHPT1 (phosphohistidine phosphatase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See janA in Genome Data Viewer
    Location:
    99D3-99D3; 3-100 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (30038622..30039533, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (25864344..25865255, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Axin Neighboring gene Zinc-finger protein interacting with CP190 Neighboring gene ocnus Neighboring gene janus B Neighboring gene Serendipity alpha Neighboring gene Serendipity beta Neighboring gene Serendipity delta

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Drosophila maternal and embryo mRNAs transcribed from a single transcription unit use alternate combinations of exons. Vincent A, et al. EMBO J, 1984 May. PMID 6329730, Free PMC Article
    2. Sequence and structure of the serendipity locus of Drosophila melanogaster. A densely transcribed region including a blastoderm-specific gene. Vincent A, et al. J Mol Biol, 1985 Nov 5. PMID 3935797
    3. Patterns of DNA sequence variation suggest the recent action of positive selection in the janus-ocnus region of Drosophila simulans. Parsch J, et al. Genetics, 2001 Oct. PMID 11606541, Free PMC Article
    4. Single amino acid exchanges in separate domains of the Drosophila serendipity delta zinc finger protein cause embryonic and sex biased lethality. Crozatier M, et al. Genetics, 1992 Aug. PMID 1516821, Free PMC Article
    5. Transcriptional and translational cis-regulatory sequences of the spermatocyte-specific Drosophila janusB gene are located in the 3' exonic region of the overlapping janusA gene. Yanicostas C, et al. Mol Gen Genet, 1990 Dec. PMID 2125114

    See all (48) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein histidine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in sex differentiation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    janus A
    Names
    CG7933-PA
    CG7933-PB
    CG7933-PC
    janA-PA
    janA-PB
    janA-PC
    janus
    NP_788762.1
    NP_788763.1
    NP_996311.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      30038622..30039533 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_206588.2 → NP_996311.1  janus A, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996311.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C7LA86
      Conserved Domains (1) summary
      pfam05005
      Location:9 → 108
      Ocnus; Janus/Ocnus family (Ocnus)

    2. NM_176586.4 → NP_788763.1  janus A, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788763.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C7LA86
      Related
      FBpp0089165
      Conserved Domains (1) summary
      pfam05005
      Location:9 → 108
      Ocnus; Janus/Ocnus family (Ocnus)

    3. NM_176585.2 → NP_788762.1  janus A, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788762.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V3M6, P20348, Q8T475, Q9VAB6
      UniProtKB/TrEMBL
      C7LA86
      Related
      FBpp0084962
      Conserved Domains (1) summary
      pfam05005
      Location:25 → 124
      Ocnus; Janus/Ocnus family (Ocnus)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P20348.2 P20348

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools