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    RpS28a Ribosomal protein S28a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43564, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RpS28aprovided by FlyBase
    Official Full Name
    Ribosomal protein S28aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039739
    Locus tag
    Dmel_CG15527
    See related
    AllianceGenome:FB:FBgn0039739
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG15527; Dmel\CG15527
    Summary
    Predicted to be a structural constituent of ribosome. Involved in wing disc development. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 15 with mandibulofacial dysostosis. Orthologous to human RPS28 (ribosomal protein S28). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See RpS28a in Genome Data Viewer
    Location:
    99D2-99D2; 3-100 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (30022345..30022648, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (25848067..25848370, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase Neighboring gene long non-coding RNA:CR46111 Neighboring gene Axin Neighboring gene antisense RNA:CR44045

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An age-downregulated ribosomal RpS28 protein variant regulates the muscle proteome. Jiao J, et al. G3 (Bethesda), 2021 Jul 14. PMID 33974070, Free PMC Article
    2. New genes in Drosophila quickly become essential. Chen S, et al. Science, 2010 Dec 17. PMID 21164016, Free PMC Article
    3. Ribosome heterogeneity in Drosophila melanogaster gonads through paralog-switching. Hopes T, et al. Nucleic Acids Res, 2022 Feb 28. PMID 34283226, Free PMC Article
    4. New genes often acquire male-specific functions but rarely become essential in Drosophila. Kondo S, et al. Genes Dev, 2017 Sep 15. PMID 29051389, Free PMC Article
    5. Gene Expression Associated with Early and Late Chronotypes in Drosophila melanogaster. Pegoraro M, et al. Front Neurol, 2015. PMID 26097463, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		  
    involved_in cytoplasmic translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in maturation of SSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosomal small subunit assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in wing disc development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of cytosolic small ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal protein S28a
    Names
    CG15527-PA
    RpS28a-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      30022345..30022648 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143507.2 → NP_651764.1  ribosomal protein S28a [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651764.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C9QPF8, Q9VAB9
      Related
      FBpp0084966
      Conserved Domains (1) summary
      cd04457
      Location:5 → 64
      S1_S28E; S1_S28E: S28E, S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. S28E protein is a component of the 30S ribosomal subunit. S28E is highly conserved among archaea and eukaryotes. S28E may ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VAB9 Q9VAB9

    Gene LinkOut

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