zbtb16b zinc finger and BTB domain containing 16b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: zbtb16bprovided by ZNC
Official Full Name: zinc finger and BTB domain containing 16bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-100923-1
See related: Ensembl:ENSDARG00000074526 AllianceGenome:ZFIN:ZDB-GENE-100923-1
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fb53a11
Summary: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within positive regulation of type I interferon production. Located in nucleus. Is expressed in several structures, including anterior neural keel; atrium; hindbrain neural keel; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in acute promyelocytic leukemia. Orthologous to human ZBTB16 (zinc finger and BTB domain containing 16). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (18253542..18361160, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (18323432..18425383, complement)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

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Function	Evidence Code	Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables DNA-binding transcription repressor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within positive regulation of type I interferon production	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info

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The following sections contain reference sequences that belong to a specific genome build. Explain