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    PCME prenylcysteine methylesterase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831443, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PCME
    Official Full Name
    prenylcysteine methylesterase
    Primary source
    TAIR:AT5G15860
    Locus tag
    AT5G15860
    See related
    Araport:AT5G15860
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATPCME; F14F8.240; F14F8_240; ICME; Isoprenylcysteine methylesterase; prenylcysteine methylesterase
    Summary
    Encodes a protein with prenylcysteine methylesterase activity.
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    Genomic context

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    See PCME in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    8
    Sequence:
    Chromosome: 5; NC_003076.8 (5178157..5181761, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene B-box type zinc finger protein with CCT domain-containing protein Neighboring gene ncRNA Neighboring gene CONSTANS-like 1 Neighboring gene uncharacterized protein Neighboring gene glycosyl hydrolase family 81 protein Neighboring gene golgin family A protein Neighboring gene TRICHOME BIREFRINGENCE-LIKE 21

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Prenylcysteine methylesterase in Arabidopsis thaliana. Deem AK, et al. Gene, 2006 Oct 1. PMID 16870359
    2. Characterization, sub-cellular localization and expression profiling of the isoprenylcysteine methylesterase gene family in Arabidopsis thaliana. Lan P, et al. BMC Plant Biol, 2010 Sep 27. PMID 20868530, Free PMC Article
    3. Ubiquitin-Mediated Proteasomal Degradation of Oleosins is Involved in Oil Body Mobilization During Post-Germinative Seedling Growth in Arabidopsis. Deruyffelaere C, et al. Plant Cell Physiol, 2015 Jul. PMID 25907570
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_121591.5
    NM_203057.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables prenylcysteine methylesterase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    prenylcysteine methylesterase
    NP_197090.2
    • prenylcysteine methylesterase (PCME); FUNCTIONS IN: prenylcysteine methylesterase activity; INVOLVED IN: metabolic process; LOCATED IN: membrane; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Carboxylesterase type B, active site (InterPro:IPR019826), Carboxylesterase, type B (InterPro:IPR002018), Alpha/beta hydrolase fold-3 (InterPro:IPR013094); BEST Arabidopsis thaliana protein match is: alpha/beta-Hydrolases superfamily protein (TAIR:AT3G02410.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_974786.1
    • prenylcysteine methylesterase (PCME); CONTAINS InterPro DOMAIN/s: Carboxylesterase type B, active site (InterPro:IPR019826), Carboxylesterase, type B (InterPro:IPR002018); BEST Arabidopsis thaliana protein match is: alpha/beta-Hydrolases superfamily protein (TAIR:AT3G02410.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      5178157..5181761 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121591.5 → NP_197090.2  prenylcysteine methylesterase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197090.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4KBA0, Q94AS5, Q9LFU2
      UniProtKB/TrEMBL
      A0A178UD10, A0A5S9Y4H3, A0A654G1E0
      Conserved Domains (1) summary
      COG0657
      Location:130 → 368
      Aes; Acetyl esterase/lipase [Lipid transport and metabolism]

    2. NM_203057.1 → NP_974786.1  prenylcysteine methylesterase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974786.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94AS5
      Conserved Domains (2) summary
      COG0657
      Location:130 → 246
      Aes; Acetyl esterase/lipase [Lipid transport and metabolism]
      cl21494
      Location:143 → 246
      Abhydrolase; alpha/beta hydrolases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94AS5.1

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