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    EMB2654 Tetratricopeptide repeat (TPR)-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818771, updated on 18-Sep-2024

    Summary

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    Official Symbol
    EMB2654
    Official Full Name
    Tetratricopeptide repeat (TPR)-like superfamily protein
    Primary source
    TAIR:AT2G41720
    Locus tag
    AT2G41720
    See related
    Araport:AT2G41720
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    EMBRYO DEFECTIVE 2654; T11A7.18; T11A7_18
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    Genomic context

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    See EMB2654 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    9
    Sequence:
    Chromosome: 2; NC_003071.7 (17403603..17407325, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene camphor resistance CrcB family protein Neighboring gene ncRNA Neighboring gene Integrase-type DNA-binding superfamily protein Neighboring gene ncRNA Neighboring gene calcium-binding site protein Neighboring gene villin 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The coordinated action of PPR4 and EMB2654 on each intron half mediates trans-splicing of rps12 transcripts in plant chloroplasts. Lee K, et al. Plant J, 2019 Dec. PMID 31442349
    2. The Pentatricopeptide Repeat Protein EMB2654 Is Essential for Trans-Splicing of a Chloroplast Small Ribosomal Subunit Transcript. Aryamanesh N, et al. Plant Physiol, 2017 Feb. PMID 28011633, Free PMC Article
    3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The coordinated action of PPR4 and EMB2654 on each intron half mediates trans-splicing of rps12 transcripts in plant chloroplasts. Arabidopsis atppr4 and rice osppr4 mutants are embryo-lethal and seedling-lethal 3 weeks after germination, respectively, showing that PPR4 is essential in the development of both dicot and monocot plants.
      Title: The coordinated action of PPR4 and EMB2654 on each intron half mediates trans-splicing of rps12 transcripts in plant chloroplasts.
    2. EMB2654 binding must be an early step in, or prior to, the formation of a large protein-RNA complex covering the free ends of the two rps12 intron halves.
      Title: The Pentatricopeptide Repeat Protein EMB2654 Is Essential for Trans-Splicing of a Chloroplast Small Ribosomal Subunit Transcript.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001336935.1
    NM_180025.2
    NM_180026.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables structural constituent of ribosome IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within chloroplast mRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo development ending in seed dormancy NAS
    Non-traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Tetratricopeptide repeat (TPR)-like superfamily protein
    NP_850356.1
    • EMBRYO DEFECTIVE 2654 (EMB2654); INVOLVED IN: embryo development ending in seed dormancy; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pentatricopeptide repeat (InterPro:IPR002885); BEST Arabidopsis thaliana protein match is: Pentatricopeptide repeat (PPR) superfamily protein (TAIR:AT5G02860.1); Has 63033 Blast hits to 15489 proteins in 313 species: Archae - 3; Bacteria - 71; Metazoa - 950; Fungi - 1085; Plants - 58248; Viruses - 0; Other Eukaryotes - 2676 (source: NCBI BLink).
    NP_850357.2
    • EMBRYO DEFECTIVE 2654 (EMB2654); INVOLVED IN: embryo development ending in seed dormancy; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pentatricopeptide repeat (InterPro:IPR002885); BEST Arabidopsis thaliana protein match is: Pentatricopeptide repeat (PPR) superfamily protein (TAIR:AT5G02860.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      17403603..17407325 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180026.2 → NP_850357.2  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850357.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      C0Z271, F4IL02
      Conserved Domains (5) summary
      TIGR00756
      Location:435 → 468
      PPR; pentatricopeptide repeat domain (PPR motif)
      sd00004
      Location:225 → 252
      PPR; PPR repeat [structural motif]
      pfam01535
      Location:82 → 112
      PPR; PPR repeat
      pfam12854
      Location:290 → 320
      PPR_1; PPR repeat
      pfam13041
      Location:291 → 340
      PPR_2; PPR repeat family

    2. NM_180025.2 → NP_850356.1  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850356.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22948, Q8RWS8
      UniProtKB/TrEMBL
      A0A178VXZ9, A0A5S9X649
      Conserved Domains (3) summary
      PLN03218
      Location:190 → 606
      PLN03218; maturation of RBCL 1; Provisional
      sd00004
      Location:357 → 384
      PPR; PPR repeat [structural motif]
      pfam13041
      Location:598 → 647
      PPR_2; PPR repeat family

    3. NM_001336935.1 → NP_001323745.1  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VWE4, A0A1P8AXX6, A0A384LB51, C0Z271
      Conserved Domains (3) summary
      PLN03218
      Location:190 → 606
      PLN03218; maturation of RBCL 1; Provisional
      sd00004
      Location:357 → 384
      PPR; PPR repeat [structural motif]
      pfam13041
      Location:598 → 647
      PPR_2; PPR repeat family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8RWS8.1

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