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    Hmgn1 high mobility group nucleosomal binding domain 1 [ Mus musculus (house mouse) ]

    Gene ID: 15312, updated on 27-Nov-2024

    Summary

    Official Symbol
    Hmgn1provided by MGI
    Official Full Name
    high mobility group nucleosomal binding domain 1provided by MGI
    Primary source
    MGI:MGI:96120
    See related
    Ensembl:ENSMUSG00000040681 AllianceGenome:MGI:96120
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Hmg14; HMG-14
    Summary
    Enables chromatin binding activity. Acts upstream of or within several processes, including nucleotide-excision repair; positive regulation of NAD+ ADP-ribosyltransferase activity; and response to UV. Located in female germ cell nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and skin. Orthologous to human HMGN1 (high mobility group nucleosome binding domain 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in CNS E11.5 (RPKM 270.4), limb E14.5 (RPKM 161.5) and 21 other tissues See more
    Orthologs
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    Genomic context

    See Hmgn1 in Genome Data Viewer
    Location:
    16 C4; 16 56.83 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (95922788..95928925, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (96121588..96127725, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr16:96212367-96212668 Neighboring gene proteasome (prosome, macropain) assembly chaperone 1 Neighboring gene STARR-seq mESC enhancer starr_41611 Neighboring gene bromodomain and WD repeat domain containing 1 Neighboring gene STARR-seq mESC enhancer starr_41612 Neighboring gene STARR-seq mESC enhancer starr_41614 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:96307304-96307505 Neighboring gene STARR-positive B cell enhancer mm9_chr16:96331382-96331682 Neighboring gene STARR-positive B cell enhancer mm9_chr16:96349246-96349547 Neighboring gene guided entry of tail-anchored proteins factor 1 Neighboring gene Leber congenital amaurosis 5-like Neighboring gene predicted gene, 53923

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4) 
    • Targeted (1)  1 citation

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC103397

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables nucleosomal DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chromatin IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in female germ cell nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    non-histone chromosomal protein HMG-14
    Names
    high mobility group nucleosome-binding domain-containing protein 1
    high mobility group protein 14

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008251.3NP_032277.3  non-histone chromosomal protein HMG-14

      See identical proteins and their annotated locations for NP_032277.3

      Status: VALIDATED

      Source sequence(s)
      AK010763, BU923172
      Consensus CDS
      CCDS28353.1
      UniProtKB/Swiss-Prot
      P18608, Q5HZY9
      UniProtKB/TrEMBL
      A0A3B2W3M7
      Related
      ENSMUSP00000061012.8, ENSMUST00000050884.16
      Conserved Domains (1) summary
      pfam01101
      Location:290
      HMG14_17; HMG14 and HMG17

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      95922788..95928925 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)