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    rpsa ribosomal protein SA [ Danio rerio (zebrafish) ]

    Gene ID: 394027, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rpsaprovided by ZNC
    Official Full Name
    ribosomal protein SAprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-811
    See related
    Ensembl:ENSDARG00000019181 AllianceGenome:ZFIN:ZDB-GENE-040426-811
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    lamr1; zgc:55831; zgc:77824
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation and ribosomal small subunit assembly. Predicted to act upstream of or within translation. Predicted to be located in several cellular components, including nucleus; plasma membrane; and ribosome. Predicted to be part of cytosolic small ribosomal subunit. Is expressed in eye. Orthologous to human RPSA (ribosomal protein SA). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See rpsa in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (7713342..7720332, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (7556173..7563163, complement)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene intraflagellar transport 56 Neighboring gene transfer RNA arginine (anticodon CCU) Neighboring gene small nucleolar RNA SNORA62/SNORA6 family Neighboring gene small nucleolar RNA SNORA62/SNORA6 family Neighboring gene small nucleolar RNA SNORA62/SNORA6 family Neighboring gene solute carrier family 25 member 38b Neighboring gene myosin, heavy chain 9a, non-muscle

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Differential protein profile in zebrafish (Danio rerio) brain under the joint exposure of methyl parathion and cadmium. Ling XP, et al. Environ Sci Pollut Res Int, 2012 Nov. PMID 22767353
    2. Oocyte-specific maternal Slbp2 is required for replication-dependent histone storage and early nuclear cleavage in zebrafish oogenesis and embryogenesis. He WX, et al. RNA, 2018 Dec. PMID 30185624, Free PMC Article
    3. Proteomic analysis of arsenic-exposed zebrafish (Danio rerio) identifies altered expression in proteins involved in fibrosis and lipid uptake in a gender-specific manner. Carlson P, et al. Toxicol Sci, 2013 Jul. PMID 23570992
    4. Many ribosomal protein mutations are associated with growth impairment and tumor predisposition in zebrafish. Lai K, et al. Dev Dyn, 2009 Jan. PMID 19097187, Free PMC Article
    5. Analysis of the zebrafish proteome during embryonic development. Lucitt MB, et al. Mol Cell Proteomics, 2008 May. PMID 18212345, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC55831

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables laminin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables laminin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosomal small subunit assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of small ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    small ribosomal subunit protein uS2
    Names
    laminin receptor 1 (ribosomal protein SA)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_201052.1 → NP_957346.1  small ribosomal subunit protein uS2

      See identical proteins and their annotated locations for NP_957346.1

      Status: PROVISIONAL

      Source sequence(s)
      BC044504
      UniProtKB/Swiss-Prot
      Q803F6
      UniProtKB/TrEMBL
      B2GNT1
      Related
      ENSDARP00000123183.2, ENSDART00000135945.4
      Conserved Domains (3) summary
      PTZ00254
      Location:1 → 249
      PTZ00254; 40S ribosomal protein SA; Provisional
      TIGR01012
      Location:10 → 206
      uS2_euk_arch; ribosomal protein uS2, eukaryotic/archaeal form
      pfam16122
      Location:202 → 308
      40S_SA_C; 40S ribosomal protein SA C-terminus

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      7713342..7720332 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q803F6.1 GenPept UniProtKB/Swiss-Prot:Q803F6

    Gene LinkOut

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