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    mycbp2 MYC binding protein 2 [ Danio rerio (zebrafish) ]

    Gene ID: 368439, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mycbp2provided by ZNC
    Official Full Name
    MYC binding protein 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030616-132
    See related
    Ensembl:ENSDARG00000001220 AllianceGenome:ZFIN:ZDB-GENE-030616-132
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    Myc; PAM; esr; til; esrom; tilsit; zft368; fa97c06; ns:zft368; xx:zft368; wu:fa97c06; si:dz12g7.1; si:dz256p4.1; si:busm1-12g7.1
    Summary
    Enables ubiquitin-protein transferase activity. Acts upstream of or within several processes, including axonogenesis; habenula development; and regulation of pteridine metabolic process. Located in cytoplasm. Is expressed in several structures, including eye; heart; integument; liver; and testis. Orthologous to human MYCBP2 (MYC binding protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See mycbp2 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    86
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (17045878..17286340, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (17038163..17278631, complement)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137490345 Neighboring gene F-box and leucine-rich repeat protein 3a Neighboring gene uncharacterized LOC137496462 Neighboring gene uncharacterized LOC137490765 Neighboring gene sciellin Neighboring gene SLAIN motif family, member 1a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Esrom, an ortholog of PAM (protein associated with c-myc), regulates pteridine synthesis in the zebrafish. Le Guyader S, et al. Dev Biol, 2005 Jan 15. PMID 15617681
    2. The ubiquitin ligase PHR promotes directional regrowth of spinal zebrafish axons. Bremer J, et al. Commun Biol, 2019. PMID 31149640, Free PMC Article
    3. Mutations affecting xanthophore pigmentation in the zebrafish, Danio rerio. Odenthal J, et al. Development, 1996 Dec. PMID 9007257
    4. Disruption of Esrom and Ryk identifies the roof plate boundary as an intermediate target for commissure formation. Hendricks M, et al. Mol Cell Neurosci, 2008 Feb. PMID 18060805
    5. PHR regulates growth cone pausing at intermediate targets through microtubule disassembly. Hendricks M, et al. J Neurosci, 2009 May 20. PMID 19458229, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PHR (Mycbp2) has a role in promoting directional regrowth of spinal zebrafish axons
      Title: The ubiquitin ligase PHR promotes directional regrowth of spinal zebrafish axons.
    2. These data identify Esrom as a mediator of growth cone navigation at an intermediate target and underscore the importance of midline boundaries as signaling centers for commissure formation.
      Title: Disruption of Esrom and Ryk identifies the roof plate boundary as an intermediate target for commissure formation.
    3. Esrom, an ortholog of PAM (protein associated with c-myc), regulates pteridine synthesis in the zebrafish.
      Title: Esrom, an ortholog of PAM (protein associated with c-myc), regulates pteridine synthesis in the zebrafish.
    4. Esrom has E3 ligase activity and modulates the amount of phosphorylated Tuberin in growth cones
      Title: Formation of the retinotectal projection requires Esrom, an ortholog of PAM (protein associated with Myc).
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables guanyl-nucleotide exchange factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables small GTPase binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin protein ligase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables ubiquitin-protein transferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anatomical structure morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within axon choice point recognition IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within axon extension involved in regeneration IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within axon extension involved in regeneration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in axon guidance IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in central nervous system projection neuron axonogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in circadian regulation of gene expression ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within developmental pigmentation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within habenula development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in neuromuscular process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of axon guidance ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of pteridine metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of synaptic assembly at neuromuscular junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within retinal ganglion cell axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within rhythmic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase MYCBP2
    Names
    protein Esrom
    NP_001012247.2
    XP_009302823.1
    XP_009302824.1
    XP_009302825.1
    XP_009302826.1
    XP_009302827.1
    XP_009302828.1
    XP_009302829.1
    XP_009302830.1
    XP_009302831.1
    XP_009302832.1
    XP_009302833.1
    XP_009302834.1
    XP_009302835.1
    XP_009302836.1
    XP_009302837.1
    XP_009302838.1
    XP_017213145.1
    XP_021334293.1
    XP_068079420.1
    XP_068079421.1
    XP_068079422.1
    XP_068079423.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012247.2 → NP_001012247.2  E3 ubiquitin-protein ligase MYCBP2

      Status: VALIDATED

      Source sequence(s)
      AL840634, BX510646, CR628366, CU138551
      UniProtKB/Swiss-Prot
      D3JU51, D3JU52, F1QI76, F1RD40, Q5IBM5, Q7ZZ57, Q8AW10
      Related
      ENSDARP00000028785.7, ENSDART00000039157.8
      Conserved Domains (6) summary
      pfam00415
      Location:943 → 991
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1221 → 1369
      PHR; PHR domain
      pfam13540
      Location:928 → 956
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd16463
      Location:4321 → 4375
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cl27659
      Location:2377 → 2428
      Filamin; Filamin/ABP280 repeat
      cl27697
      Location:527 → 716
      RCC1; Regulator of chromosome condensation (RCC1) repeat

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      17045878..17286340 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009304556.4 → XP_009302831.1  E3 ubiquitin-protein ligase MYCBP2 isoform X10

      UniProtKB/TrEMBL
      A0A8M3B5H4
      Conserved Domains (7) summary
      COG5184
      Location:615 → 974
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      pfam00415
      Location:908 → 956
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam00630
      Location:2341 → 2382
      Filamin; Filamin/ABP280 repeat
      pfam08005
      Location:1677 → 1834
      PHR; PHR domain
      pfam08239
      Location:2427 → 2487
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:674 → 703
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      pfam13639
      Location:4474 → 4527
      zf-RING_2; Ring finger domain

    2. XM_009304550.4 → XP_009302825.1  E3 ubiquitin-protein ligase MYCBP2 isoform X3

      UniProtKB/TrEMBL
      A0A8M3AVV1
      Conserved Domains (7) summary
      COG5184
      Location:615 → 1011
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      pfam00415
      Location:943 → 991
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam00630
      Location:2376 → 2417
      Filamin; Filamin/ABP280 repeat
      pfam08005
      Location:1712 → 1869
      PHR; PHR domain
      pfam08239
      Location:2462 → 2522
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:674 → 703
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      pfam13639
      Location:4509 → 4562
      zf-RING_2; Ring finger domain

    3. XM_009304554.4 → XP_009302829.1  E3 ubiquitin-protein ligase MYCBP2 isoform X8

      UniProtKB/TrEMBL
      A0A8M3BCC8
      Conserved Domains (7) summary
      COG5184
      Location:615 → 982
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      pfam00415
      Location:916 → 964
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam00630
      Location:2349 → 2390
      Filamin; Filamin/ABP280 repeat
      pfam08005
      Location:1685 → 1842
      PHR; PHR domain
      pfam08239
      Location:2435 → 2495
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:674 → 703
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      pfam13639
      Location:4482 → 4535
      zf-RING_2; Ring finger domain

    4. XM_068223322.1 → XP_068079423.1  E3 ubiquitin-protein ligase MYCBP2 isoform X22

    5. XM_009304562.4 → XP_009302837.1  E3 ubiquitin-protein ligase MYCBP2 isoform X17

      UniProtKB/TrEMBL
      A0A8M3B2K0
      Conserved Domains (6) summary
      COG5184
      Location:615 → 1019
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      pfam00415
      Location:951 → 999
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam00630
      Location:2384 → 2425
      Filamin; Filamin/ABP280 repeat
      pfam08005
      Location:1720 → 1877
      PHR; PHR domain
      pfam13540
      Location:674 → 703
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      pfam13639
      Location:4406 → 4459
      zf-RING_2; Ring finger domain

    6. XM_068223321.1 → XP_068079422.1  E3 ubiquitin-protein ligase MYCBP2 isoform X21

    7. XM_009304560.4 → XP_009302835.1  E3 ubiquitin-protein ligase MYCBP2 isoform X15

      UniProtKB/TrEMBL
      A0A8M3AVW4
      Conserved Domains (7) summary
      COG5184
      Location:615 → 1019
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      pfam00415
      Location:951 → 999
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam00630
      Location:2384 → 2425
      Filamin; Filamin/ABP280 repeat
      pfam08005
      Location:1720 → 1877
      PHR; PHR domain
      pfam08239
      Location:2470 → 2530
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:674 → 703
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      pfam13639
      Location:4418 → 4471
      zf-RING_2; Ring finger domain

    8. XM_068223320.1 → XP_068079421.1  E3 ubiquitin-protein ligase MYCBP2 isoform X20

    9. XM_021478618.2 → XP_021334293.1  E3 ubiquitin-protein ligase MYCBP2 isoform X13

      UniProtKB/TrEMBL
      A0A8M9Q4H8
      Conserved Domains (6) summary
      pfam00415
      Location:951 → 999
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam08005
      Location:1229 → 1377
      PHR; PHR domain
      pfam13540
      Location:936 → 964
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      cd16463
      Location:4455 → 4509
      RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
      cl27659
      Location:2385 → 2436
      Filamin; Filamin/ABP280 repeat
      cl27697
      Location:527 → 716
      RCC1; Regulator of chromosome condensation (RCC1) repeat

    10. XM_009304563.4 → XP_009302838.1  E3 ubiquitin-protein ligase MYCBP2 isoform X18

      UniProtKB/TrEMBL
      A0A8M3AVW8
      Conserved Domains (7) summary
      COG5184
      Location:615 → 1019
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      pfam00415
      Location:951 → 999
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam00630
      Location:2384 → 2425
      Filamin; Filamin/ABP280 repeat
      pfam08005
      Location:1720 → 1877
      PHR; PHR domain
      pfam08239
      Location:2470 → 2530
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:674 → 703
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      pfam13639
      Location:4404 → 4457
      zf-RING_2; Ring finger domain

    11. XM_009304551.4 → XP_009302826.1  E3 ubiquitin-protein ligase MYCBP2 isoform X5

      UniProtKB/TrEMBL
      A0A8M3B5G8
      Conserved Domains (7) summary
      COG5184
      Location:615 → 1019
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      pfam00415
      Location:951 → 999
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam00630
      Location:2384 → 2425
      Filamin; Filamin/ABP280 repeat
      pfam08005
      Location:1720 → 1877
      PHR; PHR domain
      pfam08239
      Location:2470 → 2530
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:674 → 703
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      pfam13639
      Location:4492 → 4545
      zf-RING_2; Ring finger domain

    12. XM_068223319.1 → XP_068079420.1  E3 ubiquitin-protein ligase MYCBP2 isoform X19

    13. XM_009304555.4 → XP_009302830.1  E3 ubiquitin-protein ligase MYCBP2 isoform X9

      UniProtKB/TrEMBL
      A0A8M3AVV8
      Conserved Domains (7) summary
      COG5184
      Location:615 → 1019
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      pfam00415
      Location:951 → 999
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam00630
      Location:2384 → 2425
      Filamin; Filamin/ABP280 repeat
      pfam08005
      Location:1720 → 1877
      PHR; PHR domain
      pfam08239
      Location:2470 → 2530
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:674 → 703
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      pfam13639
      Location:4481 → 4534
      zf-RING_2; Ring finger domain

    14. XM_009304561.4 → XP_009302836.1  E3 ubiquitin-protein ligase MYCBP2 isoform X16

      UniProtKB/TrEMBL
      A0A8M3B5H8
      Conserved Domains (7) summary
      COG5184
      Location:615 → 1019
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      pfam00415
      Location:951 → 999
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam00630
      Location:2384 → 2425
      Filamin; Filamin/ABP280 repeat
      pfam08005
      Location:1720 → 1877
      PHR; PHR domain
      pfam08239
      Location:2470 → 2530
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:674 → 703
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      pfam13639
      Location:4416 → 4469
      zf-RING_2; Ring finger domain

    15. XM_009304559.4 → XP_009302834.1  E3 ubiquitin-protein ligase MYCBP2 isoform X14

      UniProtKB/TrEMBL
      A0A8M3BCD1
      Conserved Domains (7) summary
      COG5184
      Location:615 → 1019
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      pfam00415
      Location:951 → 999
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam00630
      Location:2384 → 2425
      Filamin; Filamin/ABP280 repeat
      pfam08005
      Location:1720 → 1877
      PHR; PHR domain
      pfam08239
      Location:2470 → 2530
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:674 → 703
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      pfam13639
      Location:4429 → 4482
      zf-RING_2; Ring finger domain

    16. XM_009304558.4 → XP_009302833.1  E3 ubiquitin-protein ligase MYCBP2 isoform X12

      UniProtKB/TrEMBL
      A0A8M3AVW2
      Conserved Domains (7) summary
      COG5184
      Location:615 → 1019
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      pfam00415
      Location:951 → 999
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam00630
      Location:2384 → 2425
      Filamin; Filamin/ABP280 repeat
      pfam08005
      Location:1720 → 1877
      PHR; PHR domain
      pfam08239
      Location:2470 → 2530
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:674 → 703
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      pfam13639
      Location:4462 → 4515
      zf-RING_2; Ring finger domain

    17. XM_009304557.4 → XP_009302832.1  E3 ubiquitin-protein ligase MYCBP2 isoform X11

      UniProtKB/TrEMBL
      A0A8M3B2J4
      Conserved Domains (7) summary
      COG5184
      Location:615 → 1019
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      pfam00415
      Location:951 → 999
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam00630
      Location:2384 → 2425
      Filamin; Filamin/ABP280 repeat
      pfam08005
      Location:1720 → 1877
      PHR; PHR domain
      pfam08239
      Location:2470 → 2530
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:674 → 703
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      pfam13639
      Location:4471 → 4524
      zf-RING_2; Ring finger domain

    18. XM_009304553.4 → XP_009302828.1  E3 ubiquitin-protein ligase MYCBP2 isoform X7

      UniProtKB/TrEMBL
      A0A8M3AVV4
      Conserved Domains (7) summary
      COG5184
      Location:615 → 1019
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      pfam00415
      Location:951 → 999
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam00630
      Location:2384 → 2425
      Filamin; Filamin/ABP280 repeat
      pfam08005
      Location:1720 → 1877
      PHR; PHR domain
      pfam08239
      Location:2470 → 2530
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:674 → 703
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      pfam13639
      Location:4483 → 4536
      zf-RING_2; Ring finger domain

    19. XM_009304552.4 → XP_009302827.1  E3 ubiquitin-protein ligase MYCBP2 isoform X6

      UniProtKB/TrEMBL
      A0A8M3B2J0
      Conserved Domains (7) summary
      COG5184
      Location:615 → 1019
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      pfam00415
      Location:951 → 999
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam00630
      Location:2384 → 2425
      Filamin; Filamin/ABP280 repeat
      pfam08005
      Location:1720 → 1877
      PHR; PHR domain
      pfam08239
      Location:2470 → 2530
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:674 → 703
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      pfam13639
      Location:4484 → 4537
      zf-RING_2; Ring finger domain

    20. XM_017357656.3 → XP_017213145.1  E3 ubiquitin-protein ligase MYCBP2 isoform X4

      UniProtKB/TrEMBL
      A0A8M6Z803

    21. XM_009304549.4 → XP_009302824.1  E3 ubiquitin-protein ligase MYCBP2 isoform X2

      UniProtKB/TrEMBL
      A0A8M3BCC4
      Conserved Domains (7) summary
      COG5184
      Location:615 → 1019
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      pfam00415
      Location:951 → 999
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam00630
      Location:2384 → 2425
      Filamin; Filamin/ABP280 repeat
      pfam08005
      Location:1720 → 1877
      PHR; PHR domain
      pfam08239
      Location:2470 → 2530
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:674 → 703
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      pfam13639
      Location:4516 → 4569
      zf-RING_2; Ring finger domain

    22. XM_009304548.4 → XP_009302823.1  E3 ubiquitin-protein ligase MYCBP2 isoform X1

      UniProtKB/TrEMBL
      A0A8M3AVU9
      Conserved Domains (7) summary
      COG5184
      Location:615 → 1019
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      pfam00415
      Location:951 → 999
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam00630
      Location:2384 → 2425
      Filamin; Filamin/ABP280 repeat
      pfam08005
      Location:1720 → 1877
      PHR; PHR domain
      pfam08239
      Location:2470 → 2530
      SH3_3; Bacterial SH3 domain
      pfam13540
      Location:674 → 703
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
      pfam13639
      Location:4517 → 4570
      zf-RING_2; Ring finger domain

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394745.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      220341..485433 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395276.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      1679..148007 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_3

    Genomic

    1. NW_018395383.1 Reference GRCz11 ALT_DRER_TU_3

      Range
      14064..19592 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F1RD40.1 GenPept UniProtKB/Swiss-Prot:F1RD40

    Gene LinkOut

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