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    PPP1CA protein phosphatase 1 catalytic subunit alpha [ Bos taurus (domestic cattle) ]

    Gene ID: 516175, updated on 30-Jan-2025

    Summary

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    Official Symbol
    PPP1CAprovided by VGNC
    Official Full Name
    protein phosphatase 1 catalytic subunit alphaprovided by VGNC
    Primary source
    VGNC:VGNC:106874
    See related
    BGD:BT10197; EnsemblRapid:ENSBTAG00070030931
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PPP1CA in Genome Data Viewer
    Location:
    chromosome: 29
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 29 NC_037356.1 (45292436..45295867, complement)

    Chromosome 29 - NC_037356.1Genomic Context describing neighboring genes Neighboring gene DNA polymerase delta 4, accessory subunit Neighboring gene cardiotrophin like cytokine factor 1 Neighboring gene RAD9 checkpoint clamp component A Neighboring gene TBC1 domain family member 10C Neighboring gene uncharacterized LOC112444920 Neighboring gene carnosine synthase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037356.1 Chromosome 29 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Protein Phosphatase 1 binds strongly to the retinoblastoma protein but not to p107 or p130 in vitro and in vivo. Dunaief JL, et al. Curr Eye Res, 2002 May. PMID 12434308
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC127348

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein phosphatase PP1-alpha catalytic subunit
    Names
    PP-1A
    NP_001030393.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001035316.2 → NP_001030393.1  serine/threonine-protein phosphatase PP1-alpha catalytic subunit

      See identical proteins and their annotated locations for NP_001030393.1

      Status: PROVISIONAL

      Source sequence(s)
      BC102424
      UniProtKB/Swiss-Prot
      Q3T0E7
      UniProtKB/TrEMBL
      A0AAA9T6S1
      Related
      ENSBTAP00070042698.1, ENSBTAT00070070135.1
      Conserved Domains (1) summary
      cd07414
      Location:8 → 298
      MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037356.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      45292436..45295867 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3T0E7.1 GenPept UniProtKB/Swiss-Prot:Q3T0E7

    Gene LinkOut

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