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    GNMT glycine N-methyltransferase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 697722, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GNMTprovided by VGNC
    Official Full Name
    glycine N-methyltransferaseprovided by VGNC
    Primary source
    VGNC:VGNC:73099
    Locus tag
    EGK_14918
    See related
    Ensembl:ENSMMUG00000001393
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See GNMT in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (126379308..126382125, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (43973692..43976552)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene protein phosphatase 2 regulatory subunit B'delta Neighboring gene male-enhanced antigen 1 Neighboring gene peroxisomal biogenesis factor 6 Neighboring gene canopy FGF signaling regulator 3 Neighboring gene pre T cell antigen receptor alpha

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables S-adenosyl-L-methionine binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables glycine N-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables glycine binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in S-adenosylhomocysteine metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in S-adenosylmethionine metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in one-carbon metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein homotetramerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of gluconeogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sarcosine metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glycine N-methyltransferase
    NP_001252696.1
    XP_014991848.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001265767.1 → NP_001252696.1  glycine N-methyltransferase

      See identical proteins and their annotated locations for NP_001252696.1

      Status: PROVISIONAL

      Source sequence(s)
      JV635765
      UniProtKB/TrEMBL
      A0A8J8XRQ8, F7CZP8, G7MPC8
      Related
      ENSMMUP00000001860.2, ENSMMUT00000001973.4
      Conserved Domains (2) summary
      pfam13649
      Location:61 → 171
      Methyltransf_25; Methyltransferase domain
      cl28098
      Location:16 → 95
      Tam; Trans-aconitate methyltransferase [Energy production and conversion]

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      126379308..126382125 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015136362.2 → XP_014991848.1  glycine N-methyltransferase isoform X1

      Conserved Domains (1) summary
      pfam12847
      Location:58 → 151
      Methyltransf_18; Methyltransferase domain
    Nucleotide Protein
    Heading Accession and Version

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