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    AP2A1 adaptor related protein complex 2 subunit alpha 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 719038, updated on 17-Aug-2024

    Summary

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    Official Symbol
    AP2A1provided by VGNC
    Official Full Name
    adaptor related protein complex 2 subunit alpha 1provided by VGNC
    Primary source
    VGNC:VGNC:69962
    See related
    Ensembl:ENSMMUG00000011612
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See AP2A1 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (49750430..49798442)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (45195046..45242243)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene carnitine palmitoyltransferase 1C Neighboring gene uncharacterized LOC106994823 Neighboring gene testis specific serine kinase substrate Neighboring gene fuzzy planar cell polarity protein Neighboring gene mediator complex subunit 25 Neighboring gene PTOV1 extended AT-hook containing adaptor protein Neighboring gene polynucleotide kinase 3'-phosphatase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables clathrin adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in clathrin-dependent endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of AP-2 adaptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of membrane coat IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    AP-2 complex subunit alpha-1
    Names
    adaptor related protein complex 2 alpha 1 subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266208.2 → NP_001253137.1  AP-2 complex subunit alpha-1

      See identical proteins and their annotated locations for NP_001253137.1

      Status: PROVISIONAL

      Source sequence(s)
      JV046300
      UniProtKB/TrEMBL
      I0FPJ3, I0FPJ5
      Related
      ENSMMUP00000044364.2, ENSMMUT00000065373.2
      Conserved Domains (4) summary
      smart00809
      Location:733 → 836
      Alpha_adaptinC2; Adaptin C-terminal domain
      pfam01602
      Location:29 → 591
      Adaptin_N; Adaptin N terminal region
      pfam02296
      Location:842 → 950
      Alpha_adaptin_C; Alpha adaptin AP2, C-terminal domain
      sd00044
      Location:332 → 355
      HEAT; HEAT repeat [structural motif]

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      49750430..49798442
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015124408.2 → XP_014979894.2  AP-2 complex subunit alpha-1 isoform X1

      UniProtKB/TrEMBL
      F6PL38
      Related
      ENSMMUP00000015242.4, ENSMMUT00000016269.4
      Conserved Domains (4) summary
      smart00809
      Location:755 → 857
      Alpha_adaptinC2; Adaptin C-terminal domain
      sd00044
      Location:332 → 355
      HEAT; HEAT repeat [structural motif]
      pfam01602
      Location:29 → 591
      Adaptin_N; Adaptin N terminal region
      pfam02296
      Location:863 → 971
      Alpha_adaptin_C; Alpha adaptin AP2, C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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