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    CPL3 C-terminal domain phosphatase-like 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817919, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CPL3
    Official Full Name
    C-terminal domain phosphatase-like 3
    Primary source
    TAIR:AT2G33540
    Locus tag
    AT2G33540
    See related
    Araport:AT2G33540
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCPL3; C-terminal domain phosphatase-like 3; F4P9.31; F4P9_31
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    Genomic context

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    See CPL3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Sequence:
    Chromosome: 2; NC_003071.7 (14203401..14209192, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ATP-dependent RNA helicase Neighboring gene cysteine-rich/transmembrane domain protein A Neighboring gene serine carboxypeptidase-like 46 Neighboring gene Homeodomain-like superfamily protein Neighboring gene BUB1-related (BUB1: budding uninhibited by benzymidazol 1)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CPL2 and CPL3 act redundantly in FLC activation and flowering time regulation in Arabidopsis. Zhang Y, et al. Plant Signal Behav, 2022 Dec 31. PMID 35112651, Free PMC Article
    2. Arabidopsis CAPRICE-LIKE MYB 3 (CPL3) controls endoreduplication and flowering development in addition to trichome and root hair formation. Tominaga R, et al. Development, 2008 Apr. PMID 18305006
    3. A Molecular switch for FLOWERING LOCUS C activation determines flowering time in Arabidopsis. Shen L, et al. Plant Cell, 2022 Feb 3. PMID 34850922, Free PMC Article
    4. A genetics screen highlights emerging roles for CPL3, RST1 and URT1 in RNA metabolism and silencing. Li T, et al. Nat Plants, 2019 May. PMID 31076735
    5. Arabidopsis carboxyl-terminal domain phosphatase-like isoforms share common catalytic and interaction domains but have distinct in planta functions. Bang W, et al. Plant Physiol, 2006 Oct. PMID 16905668, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Arabidopsis CPL3 controls endoreduplication and flowering development in addition to trichrome and root hair formation.
      Title: Arabidopsis CAPRICE-LIKE MYB 3 (CPL3) controls endoreduplication and flowering development in addition to trichome and root hair formation.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001336459.1
    NM_128914.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA polymerase II CTD heptapeptide repeat phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables myosin phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of abscisic acid-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of post-transcriptional gene silencing by regulatory ncRNA IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within protein dephosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of photoperiodism, flowering IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in response to salt stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    C-terminal domain phosphatase-like 3
    NP_180912.2
    • C-terminal domain phosphatase-like 3 (CPL3); FUNCTIONS IN: phosphoprotein phosphatase activity, CTD phosphatase activity; INVOLVED IN: response to salt stress; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: FCP1-like phosphatase, phosphatase domain (InterPro:IPR011947), NLI interacting factor (InterPro:IPR004274), BRCT (InterPro:IPR001357); BEST Arabidopsis thaliana protein match is: C-terminal domain phosphatase-like 4 (TAIR:AT5G58003.1); Has 1686 Blast hits to 1267 proteins in 263 species: Archae - 0; Bacteria - 131; Metazoa - 483; Fungi - 269; Plants - 334; Viruses - 2; Other Eukaryotes - 467 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      14203401..14209192 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128914.3 → NP_180912.2  C-terminal domain phosphatase-like 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180912.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22804, Q8LL04
      UniProtKB/TrEMBL
      A0A178VZF2
      Conserved Domains (2) summary
      TIGR02250
      Location:922 → 1086
      FCP1_euk; FCP1-like phosphatase, phosphatase domain
      smart00292
      Location:1148 → 1225
      BRCT; breast cancer carboxy-terminal domain

    2. NM_001336459.1 → NP_001325202.1  C-terminal domain phosphatase-like 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B2G0, A0A7G2EGZ3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LL04.2

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