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    Trbc1 T cell receptor beta, constant region 1 [ Mus musculus (house mouse) ]

    Gene ID: 100125262, updated on 14-Nov-2024

    Summary

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    Official Symbol
    Trbc1provided by MGI
    Official Full Name
    T cell receptor beta, constant region 1provided by MGI
    Primary source
    MGI:MGI:4439726
    See related
    IMGT/GENE-DB:TRBC1; AllianceGenome:MGI:4439726
    Gene type
    other
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm16802; Tcrb-C1
    Summary
    Predicted to enable signaling receptor activity. Predicted to be located in plasma membrane. Predicted to be part of alpha-beta T cell receptor complex. Orthologous to several human genes including TRBC1 (T cell receptor beta constant 1) and TRBC2 (T cell receptor beta constant 2). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See Trbc1 in Genome Data Viewer
    Location:
    6 19.69 cM; 6 B1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (41515153..41516599)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (41538219..41539665)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene T cell receptor beta chain Neighboring gene STARR-seq mESC enhancer starr_15701 Neighboring gene T cell receptor beta joining 1-6 Neighboring gene T cell receptor beta joining 1-7 Neighboring gene T cell receptor beta joining 2-1 Neighboring gene T cell receptor beta, D region 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genomic organization and sequence of T-cell receptor beta-chain constant- and joining-region genes. Gascoigne NR, et al. Nature, 1984 Aug 2-8. PMID 6336329
    2. Dynamic expression of Cx47 in mouse brain development and in the cuprizone model of myelin plasticity. Parenti R, et al. Glia, 2010 Oct. PMID 20578039
    3. Tandem linkage and unusual RNA splicing of the T-cell receptor beta-chain variable-region genes. Chou HS, et al. Proc Natl Acad Sci U S A, 1987 Apr. PMID 3470773, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables signaling receptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of alpha-beta T cell receptor complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_006980.1 

      Range
      647425..648871
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      41515153..41516599
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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