U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Nucleotide

    • Showing Current items.

    maco1b macoilin 1b [ Danio rerio (zebrafish) ]

    Gene ID: 393435, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    maco1bprovided by ZNC
    Official Full Name
    macoilin 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1188
    See related
    Ensembl:ENSDARG00000012741 AllianceGenome:ZFIN:ZDB-GENE-040426-1188
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    tmem57b; zgc:63610
    Summary
    Predicted to enable microtubule binding activity. Predicted to be involved in chemotaxis and neuronal signal transduction. Predicted to be located in several cellular components, including axon; endoplasmic reticulum; and nucleus. Predicted to be active in nuclear membrane and rough endoplasmic reticulum membrane. Orthologous to human MACO1 (macoilin 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See maco1b in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (45524415..45572063)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (45387479..45435159)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 50A Neighboring gene Rh blood group, D antigen Neighboring gene low density lipoprotein receptor adaptor protein 1b Neighboring gene collagen alpha-6(VI) chain

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Spatio-temporal expression and distribution of collagen VI during zebrafish development. Tonelotto V, et al. Sci Rep, 2019 Dec 27. PMID 31882701, Free PMC Article
    2. Characterization of fibronectin type III domain-containing protein 5 (FNDC5) gene in chickens: Cloning, tissue expression, and regulation of its expression in the muscle by fasting and cold exposure. Li X, et al. Gene, 2015 Oct 10. PMID 26072164
    3. Evolutionary and Expression Analyses Show Co-option of khdrbs Genes for Origin of Vertebrate Brain. Wang S, et al. Front Genet, 2017. PMID 29354154, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Clone Names

    • MGC63610

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in chemotaxis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in neuronal signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within neuronal signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nuclear membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nuclear membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in rough endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in rough endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    macoilin-2
    Names
    transmembrane protein 57b

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200463.2 → NP_956757.2  macoilin-2

      See identical proteins and their annotated locations for NP_956757.2

      Status: PROVISIONAL

      Source sequence(s)
      AY845030
      UniProtKB/Swiss-Prot
      B7ZUY4, Q2TLY1
      Related
      ENSDARP00000069055.4, ENSDART00000074567.5
      Conserved Domains (3) summary
      TIGR03462
      Location:29 → 113
      CarR_dom_SF; lycopene cyclase domain
      pfam09726
      Location:2 → 697
      Macoilin; Transmembrane protein
      pfam16331
      Location:421 → 484
      TolA_bind_tri; TolA binding protein trimerization

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      45524415..45572063
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005157048.5 → XP_005157105.1  macoilin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B3V6
      Conserved Domains (3) summary
      TIGR03462
      Location:29 → 113
      CarR_dom_SF; lycopene cyclase domain
      pfam09726
      Location:2 → 696
      Macoilin; Transmembrane protein
      pfam16331
      Location:420 → 483
      TolA_bind_tri; TolA binding protein trimerization

    2. XM_021480543.2 → XP_021336218.1  macoilin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8M9Q9L5
      Conserved Domains (1) summary
      pfam09726
      Location:2 → 695
      Macoilin; Transmembrane protein
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2TLY1.1 GenPept UniProtKB/Swiss-Prot:Q2TLY1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools