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    CAPRIN2 caprin family member 2 [ Homo sapiens (human) ]

    Gene ID: 65981, updated on 27-Nov-2024

    Summary

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    Official Symbol
    CAPRIN2provided by HGNC
    Official Full Name
    caprin family member 2provided by HGNC
    Primary source
    HGNC:HGNC:21259
    See related
    Ensembl:ENSG00000110888 MIM:610375; AllianceGenome:HGNC:21259
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    EEG1; EEG-1; C1QDC1; RNG140
    Summary
    The protein encoded by this gene may regulate the transport of mRNA. It may play a role in the differentiation of erythroblasts. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
    Expression
    Ubiquitous expression in testis (RPKM 12.6), brain (RPKM 7.2) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See CAPRIN2 in Genome Data Viewer
    Location:
    12p11.21
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (30709553..30754951, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (30584217..30698047, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (30862487..30907885, complement)

    Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105369719 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_28131 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:30756793-30757482 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:30757483-30758172 Neighboring gene importin 8 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4321 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6158 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4322 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6159 Neighboring gene ReSE screen-validated silencer GRCh37_chr12:30909210-30909413 Neighboring gene uncharacterized LOC645485 Neighboring gene NANOG hESC enhancer GRCh37_chr12:30938423-30938924 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:30945898-30946399 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:30946901-30947402 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:30947403-30947902 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:30948405-30948904 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:30948905-30949406 Neighboring gene long intergenic non-protein coding RNA 941

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Polymorphisms in TRIB2 and CAPRIN2 Genes Contribute to the Susceptibility to High Myopia-Induced Cataract in Han Chinese Population. Ma B, et al. Med Sci Monit, 2023 Jan 30. PMID 36710479, Free PMC Article
    2. Cloning and characterization of a gene expressed during terminal differentiation that encodes a novel inhibitor of growth. Aerbajinai W, et al. J Biol Chem, 2004 Jan 16. PMID 14593112
    3. Upregulated lncRNA Cyclin-dependent kinase inhibitor 2B antisense RNA 1 induces the proliferation and migration of colorectal cancer by miR-378b/CAPRIN2 axis. Zheng Y, et al. Bioengineered, 2021 Dec. PMID 34511033, Free PMC Article
    4. LINC00941 promotes oral squamous cell carcinoma progression via activating CAPRIN2 and canonical WNT/β-catenin signaling pathway. Ai Y, et al. J Cell Mol Med, 2020 Sep. PMID 32691935, Free PMC Article
    5. Structural insights into the C1q domain of Caprin-2 in canonical Wnt signaling. Miao H, et al. J Biol Chem, 2014 Dec 5. PMID 25331957, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Polymorphisms in TRIB2 and CAPRIN2 Genes Contribute to the Susceptibility to High Myopia-Induced Cataract in Han Chinese Population.
      Title: Polymorphisms in TRIB2 and CAPRIN2 Genes Contribute to the Susceptibility to High Myopia-Induced Cataract in Han Chinese Population.
    2. Upregulated lncRNA Cyclin-dependent kinase inhibitor 2B antisense RNA 1 induces the proliferation and migration of colorectal cancer by miR-378b/CAPRIN2 axis.
      Title: Upregulated lncRNA Cyclin-dependent kinase inhibitor 2B antisense RNA 1 induces the proliferation and migration of colorectal cancer by miR-378b/CAPRIN2 axis.
    3. LINC00941 promotes oral squamous cell carcinoma progression via activating CAPRIN2 and canonical WNT/beta-catenin signaling pathway.
      Title: LINC00941 promotes oral squamous cell carcinoma progression via activating CAPRIN2 and canonical WNT/β-catenin signaling pathway.
    4. findings revealed an unrecognized role of Caprin-2 in facilitating LRP5/6 constitutive phosphorylation at G2/M through forming a quaternary complex with CDK14, Cyclin Y, and LRP5/6.
      Title: Activation/Proliferation-associated Protein 2 (Caprin-2) Positively Regulates CDK14/Cyclin Y-mediated Lipoprotein Receptor-related Protein 5 and 6 (LRP5/6) Constitutive Phosphorylation.
    5. Caprin-2 C1q-related domain forms a flexible homotrimer mediated by calcium, and this trimeric assembly is required for the functioning of caprin-2.
      Title: Structural insights into the C1q domain of Caprin-2 in canonical Wnt signaling.
    6. Caprin-2 promotes activation of the canonical Wnt signaling pathway by regulating LRP5/6 phosphorylation.
      Title: Caprin-2 enhances canonical Wnt signaling through regulating LRP5/6 phosphorylation.
    7. regulated expression of EEG-1 is involved in the orchestrated regulation of growth that occurs as erythroblasts shift from a highly proliferative state toward their terminal phase of differentiation.
      Title: Cloning and characterization of a gene expressed during terminal differentiation that encodes a novel inhibitor of growth.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ11391, FLJ22569, KIAA1873, MGC102894, MGC134847, MGC134848

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables signaling receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables signaling receptor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in dorsal/ventral axis specification ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in negative regulation of cell growth IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in negative regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of canonical Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of canonical Wnt signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of canonical Wnt signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of canonical Wnt signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of dendrite morphogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of dendritic spine morphogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in centrosome IDA
    Inferred from Direct Assay
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of receptor complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    caprin-2
    Names
    C1q domain-containing protein 1
    RNA granule protein 140
    cytoplasmic activation/proliferation-associated protein 2
    gastric cancer multidrug resistance-associated protein

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_029557.2 RefSeqGene

      Range
      4564..49962
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001002259.3 → NP_001002259.1  caprin-2 isoform 1

      See identical proteins and their annotated locations for NP_001002259.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1). This variant is supported by BK001102.1, which is a third party annotation described in PMID:14764709.
      Source sequence(s)
      AC010198, AK021453, AL834212, AY074490, AY074491, BC025420, BQ010043, KF455635
      UniProtKB/Swiss-Prot
      E4NKG2, Q149P6, Q149P7, Q6IMN5, Q6IMN6, Q7Z371, Q8TE70, Q8TE71, Q96RN6, Q9H667, Q9HAL4
      UniProtKB/TrEMBL
      A0A8Q3WKF3
      Related
      ENSP00000510623.1, ENST00000687797.1
      Conserved Domains (3) summary
      pfam05483
      Location:88 → 540
      SCP-1; Synaptonemal complex protein 1 (SCP-1)
      pfam00386
      Location:999 → 1124
      C1q; C1q domain
      pfam12287
      Location:628 → 929
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    2. NM_001206856.3 → NP_001193785.1  caprin-2 isoform 4

      See identical proteins and their annotated locations for NP_001193785.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) lacks an alternate in-frame exon and uses an alternate in-frame splice site in the central coding region, and uses an alternate splice site in the 3' coding region that causes a frameshift, compared to variant 1. The encoded isoform (4) has a distinct C-terminus and is shorter than isoform 1.
      Source sequence(s)
      AC010198, BC007520, BC117673, BR000870, KF455635
      Consensus CDS
      CCDS55816.1
      UniProtKB/TrEMBL
      A0A8Q3WKE7
      Related
      ENSP00000379150.2, ENST00000395805.6
      Conserved Domains (2) summary
      pfam05483
      Location:88 → 510
      SCP-1; Synaptonemal complex protein 1 (SCP-1)
      pfam12287
      Location:628 → 873
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    3. NM_001319842.2 → NP_001306771.1  caprin-2 isoform 5

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) lacks an exon in the 5' region, initiates translation at a downstream start codon, and uses an alternate in-frame splice site in the central coding region, compared to variant 1. The encoded isoform (5) has a shorter N-terminus and is shorter than isoform 1.
      Source sequence(s)
      AC010198, AY074491, KF455635
      UniProtKB/Swiss-Prot
      Q6IMN6
      Conserved Domains (2) summary
      pfam00386
      Location:665 → 790
      C1q; C1q domain
      pfam12287
      Location:287 → 601
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    4. NM_001319843.2 → NP_001306772.1  caprin-2 isoform 6

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) uses an alternate in-frame splice site in the central coding region compared to variant 1. The encoded isoform (6) is shorter than isoform 1. This variant is supported by BK001102.1, which is a third party annotation described in PMID:14764709.
      Source sequence(s)
      AC010198, BK001103, BR000870
      UniProtKB/TrEMBL
      A0A8Q3WKF3
      Conserved Domains (3) summary
      pfam05483
      Location:88 → 510
      SCP-1; Synaptonemal complex protein 1 (SCP-1)
      pfam00386
      Location:998 → 1123
      C1q; C1q domain
      pfam12287
      Location:628 → 928
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    5. NM_001319844.2 → NP_001306773.1  caprin-2 isoform 7

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR, lacks a portion of the 5' coding region, initiates translation at a downstream start codon, and lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (7) has a shorter N-terminus and is shorter than isoform 1.
      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      A0A8Q3WKF3
      Conserved Domains (5) summary
      PTZ00449
      Location:332 → 673
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam00386
      Location:883 → 1008
      C1q; C1q domain
      pfam12287
      Location:539 → 819
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam13870
      Location:45 → 138
      DUF4201; Domain of unknown function (DUF4201)
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    6. NM_001319845.2 → NP_001306774.1  caprin-2 isoform 8

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (8) has a shorter N-terminus than isoform 1. Variants 8 and 9 encode the same isoform (8).
      Source sequence(s)
      AC010198
      Consensus CDS
      CCDS91678.1
      UniProtKB/TrEMBL
      A0A8I5KZC0, A0A8Q3WKF3
      Conserved Domains (4) summary
      PTZ00121
      Location:49 → 488
      PTZ00121; MAEBL; Provisional
      pfam00386
      Location:918 → 1043
      C1q; C1q domain
      pfam12287
      Location:539 → 854
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    7. NM_001319846.2 → NP_001306775.1  caprin-2 isoform 8

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (8) has a shorter N-terminus than isoform 1. Variants 8 and 9 encode the same isoform (8).
      Source sequence(s)
      AC010198
      Consensus CDS
      CCDS91678.1
      UniProtKB/TrEMBL
      A0A8I5KZC0, A0A8Q3WKF3
      Related
      ENSP00000511879.1, ENST00000695400.1
      Conserved Domains (4) summary
      PTZ00121
      Location:49 → 488
      PTZ00121; MAEBL; Provisional
      pfam00386
      Location:918 → 1043
      C1q; C1q domain
      pfam12287
      Location:539 → 854
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    8. NM_001385498.1 → NP_001372427.1  caprin-2 isoform 9

      Status: REVIEWED

      Source sequence(s)
      AC010198, KF455635
      UniProtKB/TrEMBL
      A0A8Q3WKF3
      Conserved Domains (4) summary
      PTZ00121
      Location:130 → 569
      PTZ00121; MAEBL; Provisional
      pfam00386
      Location:978 → 1103
      C1q; C1q domain
      pfam12287
      Location:620 → 914
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:200 → 315
      Caprin-1_dimer; Caprin-1 dimerization domain

    9. NM_001385499.1 → NP_001372428.1  caprin-2 isoform 10

      Status: REVIEWED

      Source sequence(s)
      AC010198, KF455635
      UniProtKB/TrEMBL
      A0A8Q3WKF3
      Conserved Domains (5) summary
      PTZ00449
      Location:413 → 754
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG0419
      Location:76 → 258
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      pfam00386
      Location:964 → 1089
      C1q; C1q domain
      pfam12287
      Location:620 → 900
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:200 → 315
      Caprin-1_dimer; Caprin-1 dimerization domain

    10. NM_001385500.1 → NP_001372429.1  caprin-2 isoform 11

      Status: REVIEWED

      Source sequence(s)
      AC010198, KF455635
      UniProtKB/TrEMBL
      A0A8Q3WKF3
      Conserved Domains (5) summary
      PTZ00449
      Location:413 → 754
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG0419
      Location:76 → 258
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      pfam00386
      Location:963 → 1088
      C1q; C1q domain
      pfam12287
      Location:620 → 899
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:200 → 315
      Caprin-1_dimer; Caprin-1 dimerization domain

    11. NM_001385501.1 → NP_001372430.1  caprin-2 isoform 8

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Consensus CDS
      CCDS91678.1
      UniProtKB/TrEMBL
      A0A8I5KZC0, A0A8Q3WKF3
      Conserved Domains (4) summary
      PTZ00121
      Location:49 → 488
      PTZ00121; MAEBL; Provisional
      pfam00386
      Location:918 → 1043
      C1q; C1q domain
      pfam12287
      Location:539 → 854
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    12. NM_001385502.1 → NP_001372431.1  caprin-2 isoform 12

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Consensus CDS
      CCDS91677.1
      UniProtKB/TrEMBL
      A0A8Q3WKF3, F5H5J8
      Related
      ENSP00000443353.2, ENST00000542550.6
      Conserved Domains (4) summary
      PTZ00121
      Location:49 → 488
      PTZ00121; MAEBL; Provisional
      pfam00386
      Location:917 → 1042
      C1q; C1q domain
      pfam12287
      Location:539 → 853
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    13. NM_001385503.1 → NP_001372432.1  caprin-2 isoform 12

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Consensus CDS
      CCDS91677.1
      UniProtKB/TrEMBL
      A0A8Q3WKF3, F5H5J8
      Related
      ENSP00000511883.1, ENST00000695402.1
      Conserved Domains (4) summary
      PTZ00121
      Location:49 → 488
      PTZ00121; MAEBL; Provisional
      pfam00386
      Location:917 → 1042
      C1q; C1q domain
      pfam12287
      Location:539 → 853
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    14. NM_001385504.1 → NP_001372433.1  caprin-2 isoform 13

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Consensus CDS
      CCDS91676.1
      UniProtKB/TrEMBL
      A0A8Q3WKF3, F5GXI7, F5H7T6
      Related
      ENSP00000441005.2, ENST00000540584.2
      Conserved Domains (4) summary
      PTZ00121
      Location:49 → 488
      PTZ00121; MAEBL; Provisional
      pfam00386
      Location:897 → 1022
      C1q; C1q domain
      pfam12287
      Location:539 → 833
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    15. NM_001385505.1 → NP_001372434.1  caprin-2 isoform 13

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Consensus CDS
      CCDS91676.1
      UniProtKB/TrEMBL
      A0A8Q3WKF3, F5GXI7, F5H7T6
      Related
      ENSP00000511847.1, ENST00000695374.1
      Conserved Domains (4) summary
      PTZ00121
      Location:49 → 488
      PTZ00121; MAEBL; Provisional
      pfam00386
      Location:897 → 1022
      C1q; C1q domain
      pfam12287
      Location:539 → 833
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    16. NM_001385506.1 → NP_001372435.1  caprin-2 isoform 13

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Consensus CDS
      CCDS91676.1
      UniProtKB/TrEMBL
      A0A8Q3WKF3, F5GXI7, F5H7T6
      Related
      ENSP00000442295.2, ENST00000540436.6
      Conserved Domains (4) summary
      PTZ00121
      Location:49 → 488
      PTZ00121; MAEBL; Provisional
      pfam00386
      Location:897 → 1022
      C1q; C1q domain
      pfam12287
      Location:539 → 833
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    17. NM_001385507.1 → NP_001372436.1  caprin-2 isoform 7

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      A0A8Q3WKF3
      Conserved Domains (5) summary
      PTZ00449
      Location:332 → 673
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam00386
      Location:883 → 1008
      C1q; C1q domain
      pfam12287
      Location:539 → 819
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam13870
      Location:45 → 138
      DUF4201; Domain of unknown function (DUF4201)
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    18. NM_001385508.1 → NP_001372437.1  caprin-2 isoform 14

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      A0A8Q3WKF3
      Conserved Domains (5) summary
      PTZ00449
      Location:332 → 673
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam00386
      Location:882 → 1007
      C1q; C1q domain
      pfam12287
      Location:539 → 818
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam13870
      Location:45 → 138
      DUF4201; Domain of unknown function (DUF4201)
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    19. NM_001385509.1 → NP_001372438.1  caprin-2 isoform 14

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      A0A8Q3WKF3
      Conserved Domains (5) summary
      PTZ00449
      Location:332 → 673
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam00386
      Location:882 → 1007
      C1q; C1q domain
      pfam12287
      Location:539 → 818
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam13870
      Location:45 → 138
      DUF4201; Domain of unknown function (DUF4201)
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    20. NM_001385510.1 → NP_001372439.1  caprin-2 isoform 15

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      A0A8Q3WKF3
      Conserved Domains (4) summary
      PTZ00449
      Location:332 → 673
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam00386
      Location:862 → 987
      C1q; C1q domain
      pfam12287
      Location:539 → 798
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    21. NM_001385511.1 → NP_001372440.1  caprin-2 isoform 16

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      A0A8Q3SHV1
      Conserved Domains (4) summary
      PTZ00121
      Location:49 → 488
      PTZ00121; MAEBL; Provisional
      pfam00386
      Location:834 → 959
      C1q; C1q domain
      pfam12287
      Location:539 → 770
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    22. NM_001385512.1 → NP_001372441.1  caprin-2 isoform 16

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      A0A8Q3SHV1
      Conserved Domains (4) summary
      PTZ00121
      Location:49 → 488
      PTZ00121; MAEBL; Provisional
      pfam00386
      Location:834 → 959
      C1q; C1q domain
      pfam12287
      Location:539 → 770
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    23. NM_001385513.1 → NP_001372442.1  caprin-2 isoform 16

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      A0A8Q3SHV1
      Conserved Domains (4) summary
      PTZ00121
      Location:49 → 488
      PTZ00121; MAEBL; Provisional
      pfam00386
      Location:834 → 959
      C1q; C1q domain
      pfam12287
      Location:539 → 770
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    24. NM_001385514.1 → NP_001372443.1  caprin-2 isoform 17

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Consensus CDS
      CCDS91675.1
      UniProtKB/TrEMBL
      A0A8I5KRN0, A0A8Q3SHV1
      Related
      ENSP00000509126.1, ENST00000686317.1
      Conserved Domains (4) summary
      PTZ00121
      Location:49 → 488
      PTZ00121; MAEBL; Provisional
      pfam00386
      Location:833 → 958
      C1q; C1q domain
      pfam12287
      Location:539 → 769
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    25. NM_001385515.1 → NP_001372444.1  caprin-2 isoform 17

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Consensus CDS
      CCDS91675.1
      UniProtKB/TrEMBL
      A0A8I5KRN0, A0A8Q3SHV1
      Conserved Domains (4) summary
      PTZ00121
      Location:49 → 488
      PTZ00121; MAEBL; Provisional
      pfam00386
      Location:833 → 958
      C1q; C1q domain
      pfam12287
      Location:539 → 769
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    26. NM_001385516.1 → NP_001372445.1  caprin-2 isoform 39

      Status: REVIEWED

      Source sequence(s)
      AC010198, KF455635
      UniProtKB/TrEMBL
      A0A8Q3WKE7
      Conserved Domains (3) summary
      PTZ00121
      Location:321 → 569
      PTZ00121; MAEBL; Provisional
      pfam12287
      Location:620 → 935
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:200 → 315
      Caprin-1_dimer; Caprin-1 dimerization domain

    27. NM_001385518.1 → NP_001372447.1  caprin-2 isoform 18

      Status: REVIEWED

      Source sequence(s)
      AC010198, KF455635
      UniProtKB/TrEMBL
      A0A8Q3WKE7
      Related
      ENSP00000511846.1, ENST00000695373.1
      Conserved Domains (3) summary
      PTZ00121
      Location:321 → 569
      PTZ00121; MAEBL; Provisional
      pfam12287
      Location:620 → 935
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:200 → 315
      Caprin-1_dimer; Caprin-1 dimerization domain

    28. NM_001385519.1 → NP_001372448.1  caprin-2 isoform 19

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      A0A8Q3WKE7
      Conserved Domains (3) summary
      PTZ00121
      Location:240 → 488
      PTZ00121; MAEBL; Provisional
      pfam12287
      Location:539 → 854
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    29. NM_001385520.1 → NP_001372449.1  caprin-2 isoform 19

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      A0A8Q3WKE7
      Conserved Domains (3) summary
      PTZ00121
      Location:240 → 488
      PTZ00121; MAEBL; Provisional
      pfam12287
      Location:539 → 854
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    30. NM_001385521.1 → NP_001372450.1  caprin-2 isoform 20

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      A0A8Q3WKE7
      Related
      ENSP00000511564.1, ENST00000694880.1
      Conserved Domains (3) summary
      PTZ00121
      Location:240 → 488
      PTZ00121; MAEBL; Provisional
      pfam12287
      Location:539 → 853
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    31. NM_001385522.1 → NP_001372451.1  caprin-2 isoform 20

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      A0A8Q3WKE7
      Conserved Domains (3) summary
      PTZ00121
      Location:240 → 488
      PTZ00121; MAEBL; Provisional
      pfam12287
      Location:539 → 853
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    32. NM_001385523.1 → NP_001372452.1  caprin-2 isoform 21

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      A0A8Q3WKE7
      Conserved Domains (3) summary
      PTZ00121
      Location:240 → 488
      PTZ00121; MAEBL; Provisional
      pfam12287
      Location:539 → 833
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    33. NM_001385524.1 → NP_001372453.1  caprin-2 isoform 21

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      A0A8Q3WKE7
      Related
      ENSP00000511809.1, ENST00000695328.1
      Conserved Domains (3) summary
      PTZ00121
      Location:240 → 488
      PTZ00121; MAEBL; Provisional
      pfam12287
      Location:539 → 833
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    34. NM_001385525.1 → NP_001372454.1  caprin-2 isoform 21

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      A0A8Q3WKE7
      Conserved Domains (3) summary
      PTZ00121
      Location:240 → 488
      PTZ00121; MAEBL; Provisional
      pfam12287
      Location:539 → 833
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    35. NM_001385526.1 → NP_001372455.1  caprin-2 isoform 22

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      A0A8Q3WKE7
      Conserved Domains (3) summary
      PTZ00449
      Location:332 → 673
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam12287
      Location:539 → 798
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    36. NM_001385527.1 → NP_001372456.1  caprin-2 isoform 23

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      A0A8Q3WKE7
      Conserved Domains (3) summary
      PTZ00121
      Location:240 → 488
      PTZ00121; MAEBL; Provisional
      pfam12287
      Location:539 → 770
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    37. NM_001385528.1 → NP_001372457.1  caprin-2 isoform 24

      Status: REVIEWED

      Source sequence(s)
      AC010198, KF455635
      Consensus CDS
      CCDS91672.1
      Conserved Domains (2) summary
      pfam00386
      Location:666 → 791
      C1q; C1q domain
      pfam12287
      Location:287 → 602
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    38. NM_001385529.1 → NP_001372458.1  caprin-2 isoform 24

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Consensus CDS
      CCDS91672.1
      Related
      ENSP00000510181.1, ENST00000684863.1
      Conserved Domains (2) summary
      pfam00386
      Location:666 → 791
      C1q; C1q domain
      pfam12287
      Location:287 → 602
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    39. NM_001385531.1 → NP_001372460.1  caprin-2 isoform 5

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Conserved Domains (2) summary
      pfam00386
      Location:665 → 790
      C1q; C1q domain
      pfam12287
      Location:287 → 601
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    40. NM_001385532.1 → NP_001372461.1  caprin-2 isoform 5

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Conserved Domains (2) summary
      pfam00386
      Location:665 → 790
      C1q; C1q domain
      pfam12287
      Location:287 → 601
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    41. NM_001385533.1 → NP_001372462.1  caprin-2 isoform 5

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Conserved Domains (2) summary
      pfam00386
      Location:665 → 790
      C1q; C1q domain
      pfam12287
      Location:287 → 601
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    42. NM_001385534.1 → NP_001372463.1  caprin-2 isoform 5

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Conserved Domains (2) summary
      pfam00386
      Location:665 → 790
      C1q; C1q domain
      pfam12287
      Location:287 → 601
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    43. NM_001385535.1 → NP_001372464.1  caprin-2 isoform 25

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      A0A8Q3WKE7
      Conserved Domains (3) summary
      PTZ00121
      Location:240 → 488
      PTZ00121; MAEBL; Provisional
      pfam12287
      Location:539 → 749
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term
      pfam18293
      Location:119 → 234
      Caprin-1_dimer; Caprin-1 dimerization domain

    44. NM_001385537.1 → NP_001372466.1  caprin-2 isoform 26

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Conserved Domains (2) summary
      pfam00386
      Location:645 → 770
      C1q; C1q domain
      pfam12287
      Location:287 → 581
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    45. NM_001385538.1 → NP_001372467.1  caprin-2 isoform 27

      Status: REVIEWED

      Source sequence(s)
      AC010198, KF455635
      Conserved Domains (3) summary
      PTZ00121
      Location:7 → 193
      PTZ00121; MAEBL; Provisional
      pfam00386
      Location:642 → 767
      C1q; C1q domain
      pfam12287
      Location:264 → 578
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    46. NM_001385539.1 → NP_001372468.1  caprin-2 isoform 28

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Conserved Domains (3) summary
      PTZ00449
      Location:80 → 421
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam00386
      Location:631 → 756
      C1q; C1q domain
      pfam12287
      Location:287 → 567
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    47. NM_001385540.1 → NP_001372469.1  caprin-2 isoform 29

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Conserved Domains (3) summary
      PTZ00449
      Location:80 → 421
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam00386
      Location:630 → 755
      C1q; C1q domain
      pfam12287
      Location:287 → 566
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    48. NM_001385541.1 → NP_001372470.1  caprin-2 isoform 29

      Status: REVIEWED

      Source sequence(s)
      AC010198, KF455635
      Conserved Domains (3) summary
      PTZ00449
      Location:80 → 421
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam00386
      Location:630 → 755
      C1q; C1q domain
      pfam12287
      Location:287 → 566
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    49. NM_001385542.1 → NP_001372471.1  caprin-2 isoform 30

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Conserved Domains (3) summary
      PTZ00449
      Location:80 → 421
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam00386
      Location:610 → 735
      C1q; C1q domain
      pfam12287
      Location:287 → 546
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    50. NM_001385543.1 → NP_001372472.1  caprin-2 isoform 31

      Status: REVIEWED

      Source sequence(s)
      AC010198, KF455635
      Conserved Domains (3) summary
      PTZ00449
      Location:57 → 398
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam00386
      Location:608 → 733
      C1q; C1q domain
      pfam12287
      Location:264 → 544
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    51. NM_001385544.1 → NP_001372473.1  caprin-2 isoform 32

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Conserved Domains (3) summary
      PTZ00449
      Location:57 → 398
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam00386
      Location:607 → 732
      C1q; C1q domain
      pfam12287
      Location:264 → 543
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    52. NM_001385545.1 → NP_001372474.1  caprin-2 isoform 33

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Conserved Domains (3) summary
      PTZ00121
      Location:7 → 236
      PTZ00121; MAEBL; Provisional
      pfam00386
      Location:581 → 706
      C1q; C1q domain
      pfam12287
      Location:287 → 517
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    53. NM_001385546.1 → NP_001372475.1  caprin-2 isoform 34

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Conserved Domains (3) summary
      PTZ00121
      Location:7 → 193
      PTZ00121; MAEBL; Provisional
      pfam00386
      Location:559 → 684
      C1q; C1q domain
      pfam12287
      Location:264 → 495
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    54. NM_001385547.1 → NP_001372476.1  caprin-2 isoform 35

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      H3BM22
      Conserved Domains (2) summary
      PTZ00121
      Location:7 → 236
      PTZ00121; MAEBL; Provisional
      pfam12287
      Location:287 → 602
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    55. NM_001385548.1 → NP_001372477.1  caprin-2 isoform 35

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      H3BM22
      Conserved Domains (2) summary
      PTZ00121
      Location:7 → 236
      PTZ00121; MAEBL; Provisional
      pfam12287
      Location:287 → 602
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    56. NM_001385549.1 → NP_001372478.1  caprin-2 isoform 35

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      H3BM22
      Conserved Domains (2) summary
      PTZ00121
      Location:7 → 236
      PTZ00121; MAEBL; Provisional
      pfam12287
      Location:287 → 602
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    57. NM_001385550.1 → NP_001372479.1  caprin-2 isoform 36

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Consensus CDS
      CCDS91671.1
      UniProtKB/TrEMBL
      A0A8I5KSM9, H3BM22
      Related
      ENSP00000510009.1, ENST00000690126.1
      Conserved Domains (2) summary
      PTZ00121
      Location:7 → 236
      PTZ00121; MAEBL; Provisional
      pfam12287
      Location:287 → 601
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    58. NM_001385551.1 → NP_001372480.1  caprin-2 isoform 36

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Consensus CDS
      CCDS91671.1
      UniProtKB/TrEMBL
      A0A8I5KSM9, H3BM22
      Conserved Domains (2) summary
      PTZ00121
      Location:7 → 236
      PTZ00121; MAEBL; Provisional
      pfam12287
      Location:287 → 601
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    59. NM_001385552.1 → NP_001372481.1  caprin-2 isoform 36

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Consensus CDS
      CCDS91671.1
      UniProtKB/TrEMBL
      A0A8I5KSM9, H3BM22
      Conserved Domains (2) summary
      PTZ00121
      Location:7 → 236
      PTZ00121; MAEBL; Provisional
      pfam12287
      Location:287 → 601
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    60. NM_001385553.1 → NP_001372482.1  caprin-2 isoform 37

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      H3BM22
      Conserved Domains (2) summary
      PTZ00121
      Location:7 → 236
      PTZ00121; MAEBL; Provisional
      pfam12287
      Location:287 → 581
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    61. NM_001385554.1 → NP_001372483.1  caprin-2 isoform 36

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Consensus CDS
      CCDS91671.1
      UniProtKB/TrEMBL
      A0A8I5KSM9, H3BM22
      Conserved Domains (2) summary
      PTZ00121
      Location:7 → 236
      PTZ00121; MAEBL; Provisional
      pfam12287
      Location:287 → 601
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    62. NM_001385557.1 → NP_001372486.1  caprin-2 isoform 38

      Status: REVIEWED

      Source sequence(s)
      AC010198
      UniProtKB/TrEMBL
      H3BM22
      Conserved Domains (2) summary
      PTZ00449
      Location:122 → 421
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam12287
      Location:287 → 548
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    63. NM_001385559.1 → NP_001372488.1  caprin-2 isoform 26

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Conserved Domains (2) summary
      pfam00386
      Location:645 → 770
      C1q; C1q domain
      pfam12287
      Location:287 → 581
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    64. NM_001416513.1 → NP_001403442.1  caprin-2 isoform 40

      Status: REVIEWED

      Source sequence(s)
      AC010198

    65. NM_023925.5 → NP_076414.2  caprin-2 isoform 2

      See identical proteins and their annotated locations for NP_076414.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2, also known as EEGL) lacks an alternate in-frame exon and uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1.
      Source sequence(s)
      AC010198, AK021453, AL834212, AY074490, AY074491, BC025420, BQ010043, KF455635
      Consensus CDS
      CCDS8720.1
      UniProtKB/TrEMBL
      A0A8Q3SHV1
      Related
      ENSP00000298892.5, ENST00000298892.9
      Conserved Domains (3) summary
      pfam05483
      Location:88 → 510
      SCP-1; Synaptonemal complex protein 1 (SCP-1)
      pfam00386
      Location:949 → 1074
      C1q; C1q domain
      pfam12287
      Location:628 → 879
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    66. NM_032156.5 → NP_115532.3  caprin-2 isoform 3

      See identical proteins and their annotated locations for NP_115532.3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) uses an alternate in-frame splice site in the central coding region, and an alternate splice site in the 3' coding region that causes a frameshift, compared to variant 1. The encoded isoform (3) has a distinct C-terminus and is shorter than isoform 1.
      Source sequence(s)
      AC010198, BC007520, BC117672, BR000870, KF455635
      Consensus CDS
      CCDS41766.2
      UniProtKB/TrEMBL
      A0A8Q3WKE7
      Related
      ENSP00000391479.1, ENST00000417045.5
      Conserved Domains (2) summary
      pfam05483
      Location:88 → 510
      SCP-1; Synaptonemal complex protein 1 (SCP-1)
      pfam12287
      Location:628 → 928
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    RNA

    1. NR_169636.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC010198

    2. NR_169638.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC010198

    3. NR_169639.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Related
      ENST00000690233.1

    4. NR_169640.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Related
      ENST00000548676.5

    5. NR_169641.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Related
      ENST00000695369.1

    6. NR_169643.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC010198
      Related
      ENST00000695327.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

      Range
      30709553..30754951 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047429437.1 → XP_047285393.1  caprin-2 isoform X17

      UniProtKB/TrEMBL
      A0A8Q3WKC4
      Related
      ENSP00000511807.1, ENST00000695326.1

    2. XM_047429435.1 → XP_047285391.1  caprin-2 isoform X15

    3. XM_047429433.1 → XP_047285389.1  caprin-2 isoform X14

      UniProtKB/TrEMBL
      A0A8Q3SHS5
      Related
      ENSP00000511811.1, ENST00000695330.1

    4. XM_047429444.1 → XP_047285400.1  caprin-2 isoform X24

      Related
      ENSP00000415407.2, ENST00000433722.6

    5. XM_047429430.1 → XP_047285386.1  caprin-2 isoform X9

    6. XM_047429442.1 → XP_047285398.1  caprin-2 isoform X22

    7. XM_047429429.1 → XP_047285385.1  caprin-2 isoform X8

    8. XM_047429427.1 → XP_047285383.1  caprin-2 isoform X4

      UniProtKB/TrEMBL
      F5H5J8

    9. XM_047429439.1 → XP_047285395.1  caprin-2 isoform X19

    10. XM_047429438.1 → XP_047285394.1  caprin-2 isoform X18

    11. XM_047429434.1 → XP_047285390.1  caprin-2 isoform X14

      UniProtKB/TrEMBL
      A0A8Q3SHS5

    12. XM_047429428.1 → XP_047285384.1  caprin-2 isoform X7

    13. XM_047429441.1 → XP_047285397.1  caprin-2 isoform X21

    14. XM_017019854.2 → XP_016875343.1  caprin-2 isoform X6

      UniProtKB/TrEMBL
      A0A8Q3SHV1

    15. XM_006719144.4 → XP_006719207.1  caprin-2 isoform X5

      UniProtKB/TrEMBL
      A0A8Q3SHV1
      Conserved Domains (3) summary
      pfam05483
      Location:88 → 510
      SCP-1; Synaptonemal complex protein 1 (SCP-1)
      pfam00386
      Location:915 → 1040
      C1q; C1q domain
      pfam12287
      Location:628 → 845
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    16. XM_047429440.1 → XP_047285396.1  caprin-2 isoform X20

    17. XM_017019851.2 → XP_016875340.1  caprin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8Q3WKF3

    18. XM_047429432.1 → XP_047285388.1  caprin-2 isoform X13

    19. XM_017019865.2 → XP_016875354.1  caprin-2 isoform X12

      UniProtKB/TrEMBL
      A0A8Q3WKE7

    20. XM_047429426.1 → XP_047285382.1  caprin-2 isoform X3

    21. XM_047429436.1 → XP_047285392.1  caprin-2 isoform X16

    22. XM_047429425.1 → XP_047285381.1  caprin-2 isoform X1

    23. XM_006719147.4 → XP_006719210.1  caprin-2 isoform X11

      UniProtKB/TrEMBL
      A0A8Q3WKE7
      Conserved Domains (2) summary
      pfam05483
      Location:88 → 510
      SCP-1; Synaptonemal complex protein 1 (SCP-1)
      pfam12287
      Location:628 → 908
      Caprin-1_C; Cytoplasmic activation/proliferation-associated protein-1 C term

    24. XM_047429431.1 → XP_047285387.1  caprin-2 isoform X10

    25. XM_047429443.1 → XP_047285399.1  caprin-2 isoform X23

      Related
      ENSP00000438010.1, ENST00000537108.5

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060936.1 Alternate T2T-CHM13v2.0

      Range
      30584217..30698047 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054373020.1 → XP_054228995.1  caprin-2 isoform X25

    2. XM_054373030.1 → XP_054229005.1  caprin-2 isoform X17

    3. XM_054373028.1 → XP_054229003.1  caprin-2 isoform X15

    4. XM_054373026.1 → XP_054229001.1  caprin-2 isoform X14

    5. XM_054373036.1 → XP_054229011.1  caprin-2 isoform X24

    6. XM_054373021.1 → XP_054228996.1  caprin-2 isoform X9

    7. XM_054373019.1 → XP_054228994.1  caprin-2 isoform X8

    8. XM_054373015.1 → XP_054228990.1  caprin-2 isoform X4

    9. XM_054373032.1 → XP_054229007.1  caprin-2 isoform X19

    10. XM_054373031.1 → XP_054229006.1  caprin-2 isoform X18

    11. XM_054373027.1 → XP_054229002.1  caprin-2 isoform X14

    12. XM_054373018.1 → XP_054228993.1  caprin-2 isoform X7

    13. XM_054373034.1 → XP_054229009.1  caprin-2 isoform X21

    14. XM_054373017.1 → XP_054228992.1  caprin-2 isoform X6

    15. XM_054373016.1 → XP_054228991.1  caprin-2 isoform X5

    16. XM_054373033.1 → XP_054229008.1  caprin-2 isoform X20

    17. XM_054373013.1 → XP_054228988.1  caprin-2 isoform X2

    18. XM_054373025.1 → XP_054229000.1  caprin-2 isoform X13

    19. XM_054373024.1 → XP_054228999.1  caprin-2 isoform X12

    20. XM_054373014.1 → XP_054228989.1  caprin-2 isoform X3

    21. XM_054373029.1 → XP_054229004.1  caprin-2 isoform X16

    22. XM_054373012.1 → XP_054228987.1  caprin-2 isoform X1

    23. XM_054373023.1 → XP_054228998.1  caprin-2 isoform X11

    24. XM_054373022.1 → XP_054228997.1  caprin-2 isoform X10

    25. XM_054373035.1 → XP_054229010.1  caprin-2 isoform X23

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6IMN6.1 GenPept UniProtKB/Swiss-Prot:Q6IMN6

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