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    POU5F1P3 POU class 5 homeobox 1 pseudogene 3 [ Homo sapiens (human) ]

    Gene ID: 642559, updated on 2-Nov-2024

    Summary

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    Official Symbol
    POU5F1P3provided by HGNC
    Official Full Name
    POU class 5 homeobox 1 pseudogene 3provided by HGNC
    Primary source
    HGNC:HGNC:9222
    See related
    Ensembl:ENSG00000235602 AllianceGenome:HGNC:9222
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    OCT3; OCT4; OTF3; OTF-3; OTF3L; Oct-3; Oct-4; POU5F1; POU5F1L; OCT4-pg3; POU5FLC12
    Summary
    Predicted to enable DNA binding activity and DNA-binding transcription factor activity. Predicted to be involved in regulation of DNA-templated transcription. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See POU5F1P3 in Genome Data Viewer
    Location:
    12p13.31
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (8133769..8134852, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (8147349..8148432, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (8286365..8287448, complement)

    Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene complement C3a receptor 1 Neighboring gene NANOG hESC enhancer GRCh37_chr12:8229725-8230226 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr12:8234132-8235331 Neighboring gene NECAP endocytosis associated 1 Neighboring gene C-type lectin domain family 4 member A Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5929 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:8286281-8287059 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr12:8294369-8294870 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:8296489-8296988 Neighboring gene GCSH pseudogene 4 Neighboring gene zinc finger protein 705A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. In situ hybridization localizes the human OTF3 to chromosome 6p21.3-->p22 and OTF3L to 12p13. Guillaudeux T, et al. Cytogenet Cell Genet, 1993. PMID 8500351
    2. Oct4 and its pseudogenes confuse stem cell research. Liedtke S, et al. Cell Stem Cell, 2007 Oct 11. PMID 18371374
    3. Expression and differentiation between OCT4A and its Pseudogenes in human ESCs and differentiated adult somatic cells. Jez M, et al. PLoS One, 2014. PMID 24586860, Free PMC Article
    4. Differential expression of Oct4 variants and pseudogenes in normal urothelium and urothelial cancer. Wezel F, et al. Am J Pathol, 2013 Oct. PMID 23933063
    5. Multiple retropseudogenes from pluripotent cell-specific gene expression indicates a potential signature for novel gene identification. Pain D, et al. J Biol Chem, 2005 Feb 25. PMID 15640145

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Other Names

    • Octamer-binding protein 3
    • Octamer-binding protein 4
    • Octamer-binding transcription factor 3
    • POU domain class 5, transcription factor 1 pseudogene 3
    • POU domain transcription factor OCT4-pg3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_036440.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC092111, GU480907
      Related
      ENST00000428824.4

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

      Range
      8133769..8134852 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060936.1 Alternate T2T-CHM13v2.0

      Range
      8147349..8148432 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_005793.7: Suppressed sequence

      Description
      NG_005793.7: This RefSeq was permanently suppressed because it is now thought that this pseudogene is transcribed.

    2. NG_023971.1: Suppressed sequence

      Description
      NG_023971.1: This RefSeq was permanently suppressed because it is now thought that this pseudogene is transcribed.
    Nucleotide Protein
    Heading Accession and Version

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