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    nsa2 NSA2 ribosome biogenesis homolog (S. cerevisiae) [ Danio rerio (zebrafish) ]

    Gene ID: 321769, updated on 4-Jan-2025

    Summary

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    Official Symbol
    nsa2provided by ZNC
    Official Full Name
    NSA2 ribosome biogenesis homolog (S. cerevisiae)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-488
    See related
    Ensembl:ENSDARG00000007708 AllianceGenome:ZFIN:ZDB-GENE-030131-488
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb34b10; zgc:56334; wu:fb34b10
    Summary
    Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Predicted to act upstream of or within rRNA processing. Predicted to be located in nucleus. Predicted to be part of preribosome, large subunit precursor. Predicted to be active in nucleolus. Orthologous to human NSA2 (NSA2 ribosome biogenesis factor). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See nsa2 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (3789839..3796480, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (3638418..3645059, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene secretory carrier membrane protein 1 Neighboring gene torsin family 1 Neighboring gene SPOUT domain containing methyltransferase 1 Neighboring gene ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in maturation of 5.8S rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in maturation of LSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of preribosome, large subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosome biogenesis protein NSA2 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199568.2 → NP_955862.2  ribosome biogenesis protein NSA2 homolog

      Status: VALIDATED

      Source sequence(s)
      CU524608, EH457038, EH531450
      UniProtKB/TrEMBL
      A0A8M1PE36, F1QDL2
      Related
      ENSDARP00000003036.8, ENSDART00000021976.9
      Conserved Domains (2) summary
      cd11381
      Location:4 → 260
      NSA2; pre-ribosomal protein NSA2 (Nop seven-associated 2)
      pfam01201
      Location:31 → 259
      Ribosomal_S8e; Ribosomal protein S8e

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      3789839..3796480 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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