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    TDG thymine DNA glycosylase [ Gallus gallus (chicken) ]

    Gene ID: 395510, updated on 26-Nov-2024

    Summary

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    Official Symbol
    TDGprovided by CGNC
    Official Full Name
    thymine DNA glycosylaseprovided by CGNC
    Primary source
    CGNC:9652
    See related
    Ensembl:ENSGALG00010010085
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    5-MCDG
    Orthologs
    human mouse all
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    Genomic context

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    See TDG in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (54743600..54754205, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (55030894..55041510, complement)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene host cell factor C2 Neighboring gene glycosyltransferase 8 domain containing 2 Neighboring gene uncharacterized LOC121109113 Neighboring gene C12orf73 homolog Neighboring gene heat shock protein 90 beta family member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. 5-methylcytosine-DNA glycosylase activity is present in a cloned G/T mismatch DNA glycosylase associated with the chicken embryo DNA demethylation complex. Zhu B, et al. Proc Natl Acad Sci U S A, 2000 May 9. PMID 10779566, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables mismatch base pair DNA N-glycosylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in base-excision repair, AP site formation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    G/T mismatch-specific thymine DNA glycosylase
    Names
    5-methylcytosine-DNA glycosylase
    G/T mismatch DNA glycosylase
    NP_990081.1
    XP_046760015.1
    XP_046762575.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_204750.2 → NP_990081.1  G/T mismatch-specific thymine DNA glycosylase

      See identical proteins and their annotated locations for NP_990081.1

      Status: PROVISIONAL

      Source sequence(s)
      AF202114
      UniProtKB/TrEMBL
      F1NWB9, Q9PUA4
      Related
      ENSGALP00010013676.1, ENSGALT00010023953.1
      Conserved Domains (1) summary
      TIGR00584
      Location:2 → 327
      mug; mismatch-specific thymine-DNA glycosylate (mug)

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      54743600..54754205 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046904059.1 → XP_046760015.1  G/T mismatch-specific thymine DNA glycosylase isoform X1

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      55030894..55041510 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046906619.1 → XP_046762575.1  G/T mismatch-specific thymine DNA glycosylase isoform X1

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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