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    CG15864 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 50001, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG15864provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0040528
    Locus tag
    Dmel_CG15864
    See related
    AllianceGenome:FB:FBgn0040528
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG7553; Dmel\CG15864
    Summary
    Predicted to enable procollagen-proline 4-dioxygenase activity. Predicted to be active in endoplasmic reticulum. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG15864 in Genome Data Viewer
    Location:
    84F6-84F6; 3-48 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8248438..8250324)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4074160..4076046)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene mind the gap Neighboring gene pseudo Neighboring gene Replication protein A1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Novel Mutation in Brain Tumor Causes Both Neural Over-Proliferation and Neurodegeneration in Adult Drosophila. Loewen C, et al. G3 (Bethesda), 2018 Oct 3. PMID 30126833, Free PMC Article
    2. Presynaptic establishment of the synaptic cleft extracellular matrix is required for post-synaptic differentiation. Rohrbough J, et al. Genes Dev, 2007 Oct 15. PMID 17901219, Free PMC Article
    3. Modeling Neurodegenerative Disorders in Drosophila melanogaster. Bolus H, et al. Int J Mol Sci, 2020 Apr 26. PMID 32357532, Free PMC Article
    4. A pupal transcriptomic screen identifies Ral as a target of store-operated calcium entry in Drosophila neurons. Richhariya S, et al. Sci Rep, 2017 Feb 14. PMID 28195208, Free PMC Article
    5. Generation of LexA enhancer-trap lines in Drosophila by an international scholastic network. Kim ES, et al. G3 (Bethesda), 2023 Aug 30. PMID 37279923, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables L-ascorbic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables procollagen-proline 4-dioxygenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables procollagen-proline 4-dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15864-PB
    NP_652183.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      8248438..8250324
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143926.2 → NP_652183.2  uncharacterized protein Dmel_CG15864 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652183.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3DNF0, Q9VHU7
      Conserved Domains (3) summary
      smart00702
      Location:313 → 467
      P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
      pfam08336
      Location:35 → 166
      P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region
      cl00281
      Location:237 → 306
      metallo-dependent_hydrolases; Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VHU7 Q9VHU7

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