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    eps15l1a epidermal growth factor receptor pathway substrate 15-like 1a [ Danio rerio (zebrafish) ]

    Gene ID: 568170, updated on 9-Dec-2024

    Summary

    Official Symbol
    eps15l1aprovided by ZNC
    Official Full Name
    epidermal growth factor receptor pathway substrate 15-like 1aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060503-274
    See related
    Ensembl:ENSDARG00000042670 AllianceGenome:ZFIN:ZDB-GENE-060503-274
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkeyp-192m14.7
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be involved in endocytosis and endosomal transport. Predicted to be part of clathrin coat of coated pit. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human EPS15L1 (epidermal growth factor receptor pathway substrate 15 like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See eps15l1a in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (15907572..15957041, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (15885199..15930770, complement)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488916 Neighboring gene Kruppel like factor 2a Neighboring gene STIL centriolar assembly protein Neighboring gene ring finger and CCCH-type domains 1a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General protein information

    Preferred Names
    epidermal growth factor receptor substrate 15-like 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      15907572..15957041 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021469584.2XP_021325259.1  epidermal growth factor receptor substrate 15-like 1 isoform X6

      UniProtKB/TrEMBL
      A0A8M9PFY7
      Conserved Domains (3) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:408593
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    2. XM_009296315.4XP_009294590.1  epidermal growth factor receptor substrate 15-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PSY8
      Conserved Domains (3) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:407603
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    3. XM_009296318.4XP_009294593.1  epidermal growth factor receptor substrate 15-like 1 isoform X4

      UniProtKB/TrEMBL
      A0A8M3B5K3
      Conserved Domains (3) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:415600
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    4. XM_009296319.4XP_009294594.1  epidermal growth factor receptor substrate 15-like 1 isoform X5

      UniProtKB/TrEMBL
      A0A8M3AN27
      Conserved Domains (4) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:414610
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26809
      Location:657774
      Sec23_BS; Sec23/Sec24 beta-sandwich domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    5. XM_009296316.4XP_009294591.1  epidermal growth factor receptor substrate 15-like 1 isoform X3

      UniProtKB/TrEMBL
      A0A8M3AMB5
      Conserved Domains (4) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      PHA03369
      Location:814888
      PHA03369; capsid maturational protease; Provisional
      cl25732
      Location:414610
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    6. XM_009296314.4XP_009294589.1  epidermal growth factor receptor substrate 15-like 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PFY2
      Conserved Domains (3) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:414610
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    7. XM_009296320.4XP_009294595.1  epidermal growth factor receptor substrate 15-like 1 isoform X7

      UniProtKB/TrEMBL
      A0A8M3AXR7
      Conserved Domains (4) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:414610
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26247
      Location:809923
      DNA_pol3_delta2; DNA polymerase III, delta subunit
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    8. XM_021469585.2XP_021325260.1  epidermal growth factor receptor substrate 15-like 1 isoform X8

      UniProtKB/TrEMBL
      A0A8M9PVX7
      Related
      ENSDARP00000153451.1, ENSDART00000190068.1
      Conserved Domains (3) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:414610
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395099.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      206444..264890 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021473450.2XP_021329125.1  epidermal growth factor receptor substrate 15-like 1 isoform X6

      UniProtKB/TrEMBL
      A0A8M9Q7C1
      Conserved Domains (3) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:408593
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    2. XM_021473446.2XP_021329121.1  epidermal growth factor receptor substrate 15-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M9Q383
      Conserved Domains (3) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:407603
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    3. XM_021473448.2XP_021329123.1  epidermal growth factor receptor substrate 15-like 1 isoform X4

      UniProtKB/TrEMBL
      A0A8M9PQ17
      Conserved Domains (3) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:415600
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    4. XM_021473449.2XP_021329124.1  epidermal growth factor receptor substrate 15-like 1 isoform X5

      UniProtKB/TrEMBL
      A0A8M9PWD8
      Conserved Domains (4) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:414610
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26809
      Location:657774
      Sec23_BS; Sec23/Sec24 beta-sandwich domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    5. XM_021473447.2XP_021329122.1  epidermal growth factor receptor substrate 15-like 1 isoform X3

      UniProtKB/TrEMBL
      A0A8M9PDF2
      Conserved Domains (4) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      PHA03369
      Location:814888
      PHA03369; capsid maturational protease; Provisional
      cl25732
      Location:414610
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    6. XM_021473445.2XP_021329120.1  epidermal growth factor receptor substrate 15-like 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M9Q7B6
      Conserved Domains (3) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:414610
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    7. XM_021473451.2XP_021329126.1  epidermal growth factor receptor substrate 15-like 1 isoform X7

      UniProtKB/TrEMBL
      A0A8M9Q387
      Conserved Domains (4) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:414610
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26247
      Location:809923
      DNA_pol3_delta2; DNA polymerase III, delta subunit
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    8. XM_009296323.4XP_009294598.2  epidermal growth factor receptor substrate 15-like 1 isoform X8

      UniProtKB/TrEMBL
      A0A8M3AUS3
      Conserved Domains (3) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:414610
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395350.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      6953..56422 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021474462.2XP_021330137.1  epidermal growth factor receptor substrate 15-like 1 isoform X6

      UniProtKB/TrEMBL
      A0A8M9PFY7
      Conserved Domains (3) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:408593
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    2. XM_021474458.2XP_021330133.1  epidermal growth factor receptor substrate 15-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PSY8
      Conserved Domains (3) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:407603
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    3. XM_021474460.2XP_021330135.1  epidermal growth factor receptor substrate 15-like 1 isoform X4

      UniProtKB/TrEMBL
      A0A8M3B5K3
      Conserved Domains (3) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:415600
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    4. XM_021474461.2XP_021330136.1  epidermal growth factor receptor substrate 15-like 1 isoform X5

      UniProtKB/TrEMBL
      A0A8M3AN27
      Conserved Domains (4) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:414610
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26809
      Location:657774
      Sec23_BS; Sec23/Sec24 beta-sandwich domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    5. XM_021474459.2XP_021330134.1  epidermal growth factor receptor substrate 15-like 1 isoform X3

      UniProtKB/TrEMBL
      A0A8M3AMB5
      Conserved Domains (4) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      PHA03369
      Location:814888
      PHA03369; capsid maturational protease; Provisional
      cl25732
      Location:414610
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    6. XM_021474457.2XP_021330132.1  epidermal growth factor receptor substrate 15-like 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PFY2
      Conserved Domains (3) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:414610
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    7. XM_021474463.2XP_021330138.1  epidermal growth factor receptor substrate 15-like 1 isoform X7

      UniProtKB/TrEMBL
      A0A8M3AXR7
      Conserved Domains (4) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:414610
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26247
      Location:809923
      DNA_pol3_delta2; DNA polymerase III, delta subunit
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand
    8. XM_021474464.2XP_021330139.1  epidermal growth factor receptor substrate 15-like 1 isoform X8

      UniProtKB/TrEMBL
      A0A8M9PVX7
      Conserved Domains (3) summary
      smart00027
      Location:120213
      EH; Eps15 homology domain
      cl25732
      Location:414610
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27812
      Location:11101
      EF-hand_4; Cytoskeletal-regulatory complex EF hand