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    sorbs2b sorbin and SH3 domain containing 2b [ Danio rerio (zebrafish) ]

    Gene ID: 563408, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sorbs2bprovided by ZNC
    Official Full Name
    sorbin and SH3 domain containing 2bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070308-3
    See related
    Ensembl:ENSDARG00000061603 AllianceGenome:ZFIN:ZDB-GENE-070308-3
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-51g4.4
    Summary
    Acts upstream of or within regulation of heart rate. Predicted to be active in plasma membrane. Is expressed in heart. Orthologous to human SORBS2 (sorbin and SH3 domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See sorbs2b in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (29807099..29892635, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (29466783..29567748, complement)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene thiosulfate sulfurtransferase like domain containing 1 Neighboring gene cilia and flagella associated protein 96 Neighboring gene PDZ and LIM domain 3b Neighboring gene family with sequence similarity 149 member A Neighboring gene cytochrome P450, family 4, subfamily V, member 2b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Knockout of SORBS2 Protein Disrupts the Structural Integrity of Intercalated Disc and Manifests Features of Arrhythmogenic Cardiomyopathy. Ding Y, et al. J Am Heart Assoc, 2020 Sep. PMID 32808564, Free PMC Article
    2. The cytoskeleton adaptor protein Sorbs1 controls the development of lymphatic and venous vessels in zebrafish. Veloso A, et al. BMC Biol, 2024 Feb 27. PMID 38414014, Free PMC Article
    3. A modifier screen identifies DNAJB6 as a cardiomyopathy susceptibility gene. Ding Y, et al. JCI Insight, 2016 Sep 8. PMID 27642634, Free PMC Article
    4. In vivo protein trapping produces a functional expression codex of the vertebrate proteome. Clark KJ, et al. Nat Methods, 2011 Jun. PMID 21552255, Free PMC Article
    5. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of heart rate IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sorbin and SH3 domain-containing protein 2; sorbin and SH3 domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      29807099..29892635 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021481181.2 → XP_021336856.1  sorbin and SH3 domain-containing protein 2 isoform X13

      UniProtKB/TrEMBL
      A0A8M9QKZ3, A0A8M9QPF5
      Conserved Domains (5) summary
      cd11917
      Location:1640 → 1700
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1085 → 1139
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1160 → 1216
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:247 → 289
      Sorb; Sorbin homologous domain
      cl26464
      Location:363 → 596
      Atrophin-1; Atrophin-1 family

    2. XM_021481172.2 → XP_021336847.1  sorbin and SH3 domain-containing protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8M9PZP0, A0A8M9QPF5
      Conserved Domains (5) summary
      cd11917
      Location:1730 → 1790
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1175 → 1229
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1250 → 1306
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:337 → 379
      Sorb; Sorbin homologous domain
      cl26464
      Location:118 → 575
      Atrophin-1; Atrophin-1 family

    3. XM_021481182.2 → XP_021336857.1  sorbin and SH3 domain-containing protein 2 isoform X8

      UniProtKB/TrEMBL
      A0A8M9PZQ6, A0A8M9QPF5
      Related
      ENSDARP00000082437.5, ENSDART00000088004.7
      Conserved Domains (5) summary
      cd11917
      Location:1573 → 1633
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1018 → 1072
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1093 → 1149
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:180 → 222
      Sorb; Sorbin homologous domain
      cl26464
      Location:296 → 529
      Atrophin-1; Atrophin-1 family

    4. XM_021481179.2 → XP_021336854.1  sorbin and SH3 domain-containing protein 2 isoform X6

      UniProtKB/TrEMBL
      A0A8M9QGQ4, A0A8M9QPF5
      Conserved Domains (5) summary
      cd11917
      Location:1672 → 1732
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1117 → 1171
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1192 → 1248
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:279 → 321
      Sorb; Sorbin homologous domain
      cl26464
      Location:395 → 628
      Atrophin-1; Atrophin-1 family

    5. XM_021481175.2 → XP_021336850.1  sorbin and SH3 domain-containing protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A8M9QPF5, A0A8M9QPG1
      Conserved Domains (5) summary
      cd11917
      Location:1715 → 1775
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1160 → 1214
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1235 → 1291
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:369 → 411
      Sorb; Sorbin homologous domain
      cl26464
      Location:150 → 640
      Atrophin-1; Atrophin-1 family

    6. XM_021481186.2 → XP_021336861.1  sorbin and SH3 domain-containing protein 1 isoform X12

      UniProtKB/TrEMBL
      A0A8M9QKZ6
      Conserved Domains (5) summary
      cd11917
      Location:1249 → 1309
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:694 → 748
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:769 → 825
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:369 → 411
      Sorb; Sorbin homologous domain
      cl26464
      Location:150 → 607
      Atrophin-1; Atrophin-1 family

    7. XM_021481185.2 → XP_021336860.1  sorbin and SH3 domain-containing protein 2 isoform X11

      UniProtKB/TrEMBL
      A0A0R4IW85, A0A8M9QBH3, A0A8M9QPG7
      Related
      ENSDARP00000140527.2, ENSDART00000172349.2
      Conserved Domains (5) summary
      cd11917
      Location:1378 → 1438
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1207 → 1261
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1282 → 1338
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:369 → 411
      Sorb; Sorbin homologous domain
      cl26464
      Location:150 → 607
      Atrophin-1; Atrophin-1 family

    8. XM_068213353.1 → XP_068069454.1  sorbin and SH3 domain-containing protein 2 isoform X14

      UniProtKB/TrEMBL
      A0A8M9QPF5

    9. XM_021481184.2 → XP_021336859.1  sorbin and SH3 domain-containing protein 2 isoform X10

      UniProtKB/TrEMBL
      A0A8M9QGR0, A0A8M9QPF5
      Conserved Domains (5) summary
      cd11917
      Location:1480 → 1540
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1207 → 1261
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1282 → 1338
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:369 → 411
      Sorb; Sorbin homologous domain
      cl26464
      Location:150 → 607
      Atrophin-1; Atrophin-1 family

    10. XM_009291157.4 → XP_009289432.1  sorbin and SH3 domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M9QGP3, A0A8M9QPF5
      Conserved Domains (5) summary
      cd11917
      Location:1762 → 1822
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1207 → 1261
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1282 → 1338
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:369 → 411
      Sorb; Sorbin homologous domain
      cl26464
      Location:150 → 607
      Atrophin-1; Atrophin-1 family

    11. XM_021481183.2 → XP_021336858.1  sorbin and SH3 domain-containing protein 2 isoform X9

      UniProtKB/TrEMBL
      A0A8M9QBI6, A0A8M9QPF5
      Related
      ENSDARP00000151945.1, ENSDART00000192952.1
      Conserved Domains (5) summary
      cd11917
      Location:1524 → 1584
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1044 → 1100
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:131 → 173
      Sorb; Sorbin homologous domain
      cl17036
      Location:969 → 1023
      SH3; Src Homology 3 domain superfamily
      cl26464
      Location:247 → 480
      Atrophin-1; Atrophin-1 family

    12. XM_021481176.2 → XP_021336851.1  sorbin and SH3 domain-containing protein 2 isoform X5

      UniProtKB/TrEMBL
      A0A8M9QKZ0, A0A8M9QPF5
      Conserved Domains (5) summary
      cd11917
      Location:1713 → 1773
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1158 → 1212
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1233 → 1289
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:320 → 362
      Sorb; Sorbin homologous domain
      cl26464
      Location:101 → 558
      Atrophin-1; Atrophin-1 family

    13. XM_021481171.2 → XP_021336846.1  sorbin and SH3 domain-containing protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8M9QKY3, A0A8M9QPF5
      Conserved Domains (5) summary
      cd11917
      Location:1745 → 1805
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1190 → 1244
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1265 → 1321
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:352 → 394
      Sorb; Sorbin homologous domain
      cl26464
      Location:133 → 590
      Atrophin-1; Atrophin-1 family

    14. XM_021481180.2 → XP_021336855.1  sorbin and SH3 domain-containing protein 2 isoform X7

      UniProtKB/TrEMBL
      A0A8M9QBI2, A0A8M9QPG5
      Conserved Domains (4) summary
      cd11920
      Location:1207 → 1261
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1282 → 1338
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:369 → 411
      Sorb; Sorbin homologous domain
      cl26464
      Location:150 → 607
      Atrophin-1; Atrophin-1 family

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394913.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      147813..249715 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017359127.3 → XP_017214616.2  sorbin and SH3 domain-containing protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8M6Z492, A0A8M9PUE0
      Conserved Domains (5) summary
      cd11917
      Location:1730 → 1790
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1175 → 1229
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1250 → 1306
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:337 → 379
      Sorb; Sorbin homologous domain
      cl26464
      Location:118 → 575
      Atrophin-1; Atrophin-1 family

    2. XM_021472798.2 → XP_021328473.1  sorbin and SH3 domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PN75, A0A8M9PUE0
      Conserved Domains (5) summary
      cd11917
      Location:1762 → 1822
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1207 → 1261
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1282 → 1338
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:369 → 411
      Sorb; Sorbin homologous domain
      cl26464
      Location:150 → 607
      Atrophin-1; Atrophin-1 family

    3. XM_021472803.2 → XP_021328478.1  sorbin and SH3 domain-containing protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8M6Z492, A0A8M9PUE0
      Conserved Domains (5) summary
      cd11917
      Location:1730 → 1790
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1175 → 1229
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1250 → 1306
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:337 → 379
      Sorb; Sorbin homologous domain
      cl26464
      Location:118 → 575
      Atrophin-1; Atrophin-1 family

    4. XM_021472812.2 → XP_021328487.1  sorbin and SH3 domain-containing protein 2 isoform X8

      UniProtKB/TrEMBL
      A0A8M9PBP1, A0A8M9PUE0
      Conserved Domains (5) summary
      cd11917
      Location:1573 → 1633
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1093 → 1149
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:180 → 222
      Sorb; Sorbin homologous domain
      cl17036
      Location:1018 → 1072
      SH3; Src Homology 3 domain superfamily
      cl26464
      Location:296 → 529
      Atrophin-1; Atrophin-1 family

    5. XM_021472810.2 → XP_021328485.1  sorbin and SH3 domain-containing protein 2 isoform X6

      UniProtKB/TrEMBL
      A0A8M9PUE0, A0A8M9Q586
      Conserved Domains (5) summary
      cd11917
      Location:1672 → 1732
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1117 → 1171
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1192 → 1248
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:279 → 321
      Sorb; Sorbin homologous domain
      cl26464
      Location:395 → 628
      Atrophin-1; Atrophin-1 family

    6. XM_021472806.2 → XP_021328481.1  sorbin and SH3 domain-containing protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A8M9PUE0, A0A8M9Q1G6
      Conserved Domains (5) summary
      cd11917
      Location:1715 → 1775
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1160 → 1214
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1235 → 1291
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:369 → 411
      Sorb; Sorbin homologous domain
      cl26464
      Location:150 → 601
      Atrophin-1; Atrophin-1 family

    7. XM_021472816.2 → XP_021328491.1  sorbin and SH3 domain-containing protein 1 isoform X12

      UniProtKB/TrEMBL
      A0A8M9Q1H4
      Conserved Domains (5) summary
      cd11917
      Location:1249 → 1309
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:694 → 748
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:769 → 825
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:369 → 411
      Sorb; Sorbin homologous domain
      cl26464
      Location:150 → 607
      Atrophin-1; Atrophin-1 family

    8. XM_021472815.2 → XP_021328490.1  sorbin and SH3 domain-containing protein 2 isoform X11

      UniProtKB/TrEMBL
      A0A8M9Q589, A0A8M9QBH3
      Conserved Domains (5) summary
      cd11917
      Location:1378 → 1438
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1207 → 1261
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1282 → 1338
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:369 → 411
      Sorb; Sorbin homologous domain
      cl26464
      Location:150 → 607
      Atrophin-1; Atrophin-1 family

    9. XM_068218758.1 → XP_068074859.1  sorbin and SH3 domain-containing protein 2 isoform X18

      UniProtKB/TrEMBL
      A0A8M9PUE0

    10. XM_021472814.2 → XP_021328489.1  sorbin and SH3 domain-containing protein 2 isoform X10

      UniProtKB/TrEMBL
      A0A8M9PUE0, A0A8M9PUF2
      Conserved Domains (5) summary
      cd11917
      Location:1480 → 1540
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1207 → 1261
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1282 → 1338
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:369 → 411
      Sorb; Sorbin homologous domain
      cl26464
      Location:150 → 607
      Atrophin-1; Atrophin-1 family

    11. XM_021472802.2 → XP_021328477.1  sorbin and SH3 domain-containing protein 2 isoform X15

      UniProtKB/TrEMBL
      A0A8M9PBN2, A0A8M9PUE0
      Conserved Domains (5) summary
      cd11917
      Location:1744 → 1804
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1207 → 1261
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1282 → 1338
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:369 → 411
      Sorb; Sorbin homologous domain
      cl26464
      Location:150 → 607
      Atrophin-1; Atrophin-1 family

    12. XM_021472804.2 → XP_021328479.1  sorbin and SH3 domain-containing protein 2 isoform X16

      UniProtKB/TrEMBL
      A0A8M9PUE4, A0A8M9QBH3
      Conserved Domains (5) summary
      cd11917
      Location:1724 → 1784
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1207 → 1261
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1282 → 1338
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:369 → 411
      Sorb; Sorbin homologous domain
      cl26464
      Location:150 → 607
      Atrophin-1; Atrophin-1 family

    13. XM_021472797.2 → XP_021328472.1  sorbin and SH3 domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PN75, A0A8M9PUE0
      Conserved Domains (5) summary
      cd11917
      Location:1762 → 1822
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1207 → 1261
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1282 → 1338
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:369 → 411
      Sorb; Sorbin homologous domain
      cl26464
      Location:150 → 607
      Atrophin-1; Atrophin-1 family

    14. XM_021472813.2 → XP_021328488.1  sorbin and SH3 domain-containing protein 2 isoform X9

      UniProtKB/TrEMBL
      A0A8M9PN90, A0A8M9PUE0
      Conserved Domains (5) summary
      cd11917
      Location:1524 → 1584
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1044 → 1100
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:131 → 173
      Sorb; Sorbin homologous domain
      cl17036
      Location:969 → 1023
      SH3; Src Homology 3 domain superfamily
      cl26464
      Location:247 → 480
      Atrophin-1; Atrophin-1 family

    15. XM_021472807.2 → XP_021328482.1  sorbin and SH3 domain-containing protein 2 isoform X5

      UniProtKB/TrEMBL
      A0A8M9PN86, A0A8M9PUE0
      Conserved Domains (5) summary
      cd11917
      Location:1713 → 1773
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1158 → 1212
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1233 → 1289
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:320 → 362
      Sorb; Sorbin homologous domain
      cl26464
      Location:101 → 558
      Atrophin-1; Atrophin-1 family

    16. XM_021472801.2 → XP_021328476.1  sorbin and SH3 domain-containing protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PUE0, A0A8M9Q580
      Conserved Domains (5) summary
      cd11917
      Location:1745 → 1805
      SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11920
      Location:1190 → 1244
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1265 → 1321
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:352 → 394
      Sorb; Sorbin homologous domain
      cl26464
      Location:133 → 590
      Atrophin-1; Atrophin-1 family

    17. XM_021472809.2 → XP_021328484.1  sorbin and SH3 domain-containing protein 2 isoform X17

      UniProtKB/TrEMBL
      A0A8M9PUE8, A0A8M9QBI2
      Conserved Domains (4) summary
      cd11920
      Location:1207 → 1261
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1282 → 1338
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:369 → 411
      Sorb; Sorbin homologous domain
      cl26464
      Location:150 → 607
      Atrophin-1; Atrophin-1 family

    18. XM_021472811.2 → XP_021328486.1  sorbin and SH3 domain-containing protein 2 isoform X7

      UniProtKB/TrEMBL
      A0A8M9Q1H1, A0A8M9QBI2
      Conserved Domains (4) summary
      cd11920
      Location:1207 → 1261
      SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      cd11923
      Location:1282 → 1338
      SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
      pfam02208
      Location:369 → 411
      Sorb; Sorbin homologous domain
      cl26464
      Location:150 → 607
      Atrophin-1; Atrophin-1 family
    Nucleotide Protein Strain
    Heading Accession and Version

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