dlg1a discs large MAGUK scaffold protein 1a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: dlg1aprovided by ZNC
Official Full Name: discs large MAGUK scaffold protein 1aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-010724-8
See related: Ensembl:ENSDARG00000009677 AllianceGenome:ZFIN:ZDB-GENE-010724-8
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: dlg1; Dlgh1; SAP-97A; zgc:55810; wu:fc34d02
Summary: Predicted to enable ionotropic glutamate receptor binding activity; phosphatase binding activity; and protein kinase binding activity. Predicted to be involved in several processes, including actin cytoskeleton organization; epithelial structure maintenance; and negative regulation of G1/S transition of mitotic cell cycle. Predicted to be located in anchoring junction; apical plasma membrane; and endoplasmic reticulum membrane. Predicted to be active in several cellular components, including basolateral plasma membrane; neuromuscular junction; and postsynaptic density membrane. Is expressed in several structures, including heart; nervous system; neural tube; pigment cell; and trigeminal placode. Human ortholog(s) of this gene implicated in invasive ductal carcinoma. Orthologous to human DLG1 (discs large MAGUK scaffold protein 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 6

Exon count:: 37

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (29860971..30082920)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (29870255..30092359)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

G47531 (e-PCR)
- UniSTS:108306

fc34d02.x1 (e-PCR)
- UniSTS:193603

AI723230 (e-PCR)
- UniSTS:205968

G39264 (e-PCR)
- UniSTS:2495

fj45e06.x1 (e-PCR)
- UniSTS:199382

fj87a09.x1 (e-PCR)
- UniSTS:200176

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ionotropic glutamate receptor binding	IBA Inferred from Biological aspect of Ancestor more info
enables kinase binding	IEA Inferred from Electronic Annotation more info
enables phosphatase binding	ISS Inferred from Sequence or Structural Similarity more info
enables protein kinase binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in actin filament organization	ISS Inferred from Sequence or Structural Similarity more info
involved_in cell-cell adhesion	IBA Inferred from Biological aspect of Ancestor more info
involved_in cell-cell adhesion	ISS Inferred from Sequence or Structural Similarity more info
involved_in chemical synaptic transmission	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within chemical synaptic transmission	IEA Inferred from Electronic Annotation more info
involved_in cortical actin cytoskeleton organization	ISS Inferred from Sequence or Structural Similarity more info
involved_in endothelial cell proliferation	ISS Inferred from Sequence or Structural Similarity more info
involved_in epithelial structure maintenance	ISS Inferred from Sequence or Structural Similarity more info
involved_in establishment or maintenance of epithelial cell apical/basal polarity	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of G1/S transition of mitotic cell cycle	ISS Inferred from Sequence or Structural Similarity more info
involved_in nervous system development	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein localization to synapse	IBA Inferred from Biological aspect of Ancestor more info
involved_in receptor clustering	IBA Inferred from Biological aspect of Ancestor more info
involved_in receptor localization to synapse	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of postsynaptic membrane neurotransmitter receptor levels	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in anchoring junction	IEA Inferred from Electronic Annotation more info
located_in apical plasma membrane	IEA Inferred from Electronic Annotation more info
is_active_in basolateral plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in basolateral plasma membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in neuromuscular junction	IBA Inferred from Biological aspect of Ancestor more info
located_in neuromuscular junction	IEA Inferred from Electronic Annotation more info
is_active_in neuron projection	IBA Inferred from Biological aspect of Ancestor more info
located_in neuron projection	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
is_active_in postsynaptic density membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: disks large homolog 1

Names: SAP97A; synapse-associated protein 97A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199526.1 → NP_955820.1 disks large homolog 1

See identical proteins and their annotated locations for NP_955820.1

Status: PROVISIONAL

Source sequence(s)

BC048066

UniProtKB/Swiss-Prot

Q5PYH6, Q7ZUM2

UniProtKB/TrEMBL

A0A8M2BDE8

Related

ENSDARP00000140987.2, ENSDART00000166782.2

Conserved Domains (7) summary

smart00072
Location:693 → 860

GuKc; Guanylate kinase homologues

smart00228
Location:471 → 555

PDZ; Domain present in PSD-95, Dlg, and ZO-1/2

cd00992
Location:230 → 314

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:682 → 860

Guanylate_kin; Guanylate kinase

pfam09058
Location:4 → 62

L27_1; L27_1

pfam10600
Location:410 → 473

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:109 → 229

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007117.7 Reference GRCz11 Primary Assembly

Range

29860971..30082920

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_068221613.1 → XP_068077714.1 disks large homolog 1 isoform X1

UniProtKB/TrEMBL

A0A8M2BDE8
XM_068221614.1 → XP_068077715.1 disks large homolog 1 isoform X2

UniProtKB/TrEMBL

A0A8M2BDE8
XM_068221615.1 → XP_068077716.1 disks large homolog 1 isoform X3

UniProtKB/TrEMBL

A0A8M3ATC7
XM_068221616.1 → XP_068077717.1 disks large homolog 1 isoform X8

UniProtKB/TrEMBL

A0A8M2BDA9
XM_005165898.5 → XP_005165955.1 disks large homolog 1 isoform X4

UniProtKB/TrEMBL

A0A8M2BDA2, A0A8M2BDE8

Conserved Domains (8) summary

smart00072
Location:755 → 922

GuKc; Guanylate kinase homologues

smart00228
Location:472 → 556

PDZ; Domain present in PSD-95, Dlg, and ZO-1/2

cd00992
Location:231 → 315

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:744 → 922

Guanylate_kin; Guanylate kinase

pfam09058
Location:4 → 62

L27_1; L27_1

pfam10600
Location:411 → 474

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:109 → 230

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

cl17036
Location:588 → 661

SH3; Src Homology 3 domain superfamily
XM_005165899.5 → XP_005165956.1 disks large homolog 1 isoform X5

UniProtKB/TrEMBL

A0A8M2BD78, A0A8M2BDE8

Conserved Domains (8) summary

cd11861
Location:593 → 653

SH3_DLG-like; Src Homology 3 domain of Disks large homolog proteins

smart00072
Location:754 → 921

GuKc; Guanylate kinase homologues

smart00228
Location:471 → 555

PDZ; Domain present in PSD-95, Dlg, and ZO-1/2

cd00992
Location:230 → 314

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:743 → 921

Guanylate_kin; Guanylate kinase

pfam09058
Location:4 → 62

L27_1; L27_1

pfam10600
Location:410 → 473

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:109 → 229

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_009302399.4 → XP_009300674.1 disks large homolog 1 isoform X6

UniProtKB/TrEMBL

A0A8M2BDE8, A0A8M3B0G8

Conserved Domains (8) summary

cd11861
Location:593 → 653

SH3_DLG-like; Src Homology 3 domain of Disks large homolog proteins

smart00072
Location:753 → 920

GuKc; Guanylate kinase homologues

smart00228
Location:471 → 555

PDZ; Domain present in PSD-95, Dlg, and ZO-1/2

cd00992
Location:230 → 314

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:742 → 920

Guanylate_kin; Guanylate kinase

pfam09058
Location:4 → 62

L27_1; L27_1

pfam10600
Location:410 → 473

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:109 → 229

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_068221618.1 → XP_068077719.1 disks large homolog 1 isoform X10

UniProtKB/TrEMBL

A0A8M3ATC7

Related

ENSDARP00000036537.8, ENSDART00000028406.10
XM_005165901.5 → XP_005165958.1 disks large homolog 1 isoform X7

UniProtKB/TrEMBL

A0A8M2BD74, A0A8M2BDE8

Conserved Domains (8) summary

cd11861
Location:592 → 652

SH3_DLG-like; Src Homology 3 domain of Disks large homolog proteins

smart00072
Location:753 → 920

GuKc; Guanylate kinase homologues

smart00228
Location:470 → 554

PDZ; Domain present in PSD-95, Dlg, and ZO-1/2

cd00992
Location:229 → 313

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:742 → 920

Guanylate_kin; Guanylate kinase

pfam09058
Location:4 → 62

L27_1; L27_1

pfam10600
Location:409 → 472

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:109 → 228

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_009302391.4 → XP_009300666.1 disks large homolog 1 isoform X11

UniProtKB/TrEMBL

A0A8M2BDE8, A0A8M3B3F8

Conserved Domains (8) summary

cd11861
Location:558 → 618

SH3_DLG-like; Src Homology 3 domain of Disks large homolog proteins

smart00072
Location:719 → 886

GuKc; Guanylate kinase homologues

smart00228
Location:436 → 520

PDZ; Domain present in PSD-95, Dlg, and ZO-1/2

cd00992
Location:195 → 279

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:708 → 886

Guanylate_kin; Guanylate kinase

pfam09058
Location:4 → 62

L27_1; L27_1

pfam10600
Location:375 → 438

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:109 → 194

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_005165904.5 → XP_005165961.1 disks large homolog 1 isoform X12

UniProtKB/TrEMBL

A0A8M2BD79, A0A8M2BDE8

Conserved Domains (8) summary

cd11861
Location:558 → 618

SH3_DLG-like; Src Homology 3 domain of Disks large homolog proteins

smart00072
Location:718 → 885

GuKc; Guanylate kinase homologues

smart00228
Location:436 → 520

PDZ; Domain present in PSD-95, Dlg, and ZO-1/2

cd00992
Location:195 → 279

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:707 → 885

Guanylate_kin; Guanylate kinase

pfam09058
Location:4 → 62

L27_1; L27_1

pfam10600
Location:375 → 438

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:109 → 194

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_068221620.1 → XP_068077721.1 disks large homolog 1 isoform X15

UniProtKB/TrEMBL

A0A8M3ATC7
XM_005165908.5 → XP_005165965.1 disks large homolog 1 isoform X18

UniProtKB/TrEMBL

A0A8M2BDA9, A0A8M2BDF3

Conserved Domains (8) summary

smart00072
Location:680 → 847

GuKc; Guanylate kinase homologues

smart00228
Location:436 → 520

PDZ; Domain present in PSD-95, Dlg, and ZO-1/2

cd00992
Location:195 → 279

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:669 → 847

Guanylate_kin; Guanylate kinase

pfam09058
Location:4 → 62

L27_1; L27_1

pfam10600
Location:375 → 438

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:109 → 194

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

cl17036
Location:552 → 625

SH3; Src Homology 3 domain superfamily
XM_068221621.1 → XP_068077722.1 disks large homolog 1 isoform X16

UniProtKB/TrEMBL

A0A8M9Q5X6
XM_068221622.1 → XP_068077723.1 disks large homolog 1 isoform X17

UniProtKB/TrEMBL

A0A8M9QF49
XM_021476757.2 → XP_021332432.1 disks large homolog 1 isoform X24

UniProtKB/TrEMBL

A0A8M9PLT3, A0A8M9QF49

Related

ENSDARP00000134848.2, ENSDART00000169687.2

Conserved Domains (6) summary

smart00228
Location:336 → 420

PDZ; Domain present in PSD-95, Dlg, and ZO-1/2

cd00992
Location:95 → 179

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:569 → 747

Guanylate_kin; Guanylate kinase

pfam10600
Location:275 → 338

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:10 → 94

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

cl17036
Location:452 → 525

SH3; Src Homology 3 domain superfamily
XM_068221619.1 → XP_068077720.1 disks large homolog 1 isoform X13

UniProtKB/TrEMBL

A0A8M9QF49
XM_005165909.5 → XP_005165966.1 disks large homolog 1 isoform X19

UniProtKB/TrEMBL

A0A8M2BD80, A0A8M9QF49

Conserved Domains (7) summary

smart00072
Location:680 → 847

GuKc; Guanylate kinase homologues

smart00228
Location:397 → 481

PDZ; Domain present in PSD-95, Dlg, and ZO-1/2

cd00992
Location:156 → 240

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:669 → 847

Guanylate_kin; Guanylate kinase

pfam10600
Location:336 → 399

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:34 → 155

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

cl17036
Location:513 → 586

SH3; Src Homology 3 domain superfamily
XM_021476756.2 → XP_021332431.1 disks large homolog 1 isoform X20

UniProtKB/TrEMBL

A0A8M9QA35, A0A8M9QF49

Conserved Domains (6) summary

smart00228
Location:361 → 445

PDZ; Domain present in PSD-95, Dlg, and ZO-1/2

cd00992
Location:120 → 204

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:633 → 811

Guanylate_kin; Guanylate kinase

pfam10600
Location:300 → 363

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:34 → 119

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

cl17036
Location:477 → 550

SH3; Src Homology 3 domain superfamily
XM_021476753.2 → XP_021332428.2 disks large homolog 1 isoform X23

UniProtKB/TrEMBL

A0A8M9PZE0
XM_005165911.5 → XP_005165968.1 disks large homolog 1 isoform X21

UniProtKB/TrEMBL

A0A8M2BD84, A0A8M9QF49

Conserved Domains (7) summary

cd11861
Location:465 → 525

SH3_DLG-like; Src Homology 3 domain of Disks large homolog proteins

smart00072
Location:626 → 793

GuKc; Guanylate kinase homologues

smart00228
Location:343 → 427

PDZ; Domain present in PSD-95, Dlg, and ZO-1/2

cd00992
Location:102 → 186

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:615 → 793

Guanylate_kin; Guanylate kinase

pfam10600
Location:282 → 345

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:72 → 101

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_005165913.5 → XP_005165970.1 disks large homolog 1 isoform X22

UniProtKB/TrEMBL

A0A8M2BDB9, A0A8M9QF49

Conserved Domains (7) summary

smart00072
Location:601 → 768

GuKc; Guanylate kinase homologues

smart00228
Location:343 → 427

PDZ; Domain present in PSD-95, Dlg, and ZO-1/2

cd00992
Location:102 → 186

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:590 → 768

Guanylate_kin; Guanylate kinase

pfam10600
Location:282 → 345

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:72 → 101

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

cl17036
Location:459 → 532

SH3; Src Homology 3 domain superfamily
XM_068221623.1 → XP_068077724.1 disks large homolog 1 isoform X21

UniProtKB/TrEMBL

A0A8M2BD84, A0A8M9QF49
XM_068221617.1 → XP_068077718.1 disks large homolog 1 isoform X9

UniProtKB/TrEMBL

A0A8M9QF49
XM_005165907.5 → XP_005165964.1 disks large homolog 1 isoform X14

UniProtKB/TrEMBL

A0A8M2BD86, A0A8M9QF49

Conserved Domains (7) summary

smart00072
Location:703 → 870

GuKc; Guanylate kinase homologues

smart00228
Location:420 → 504

PDZ; Domain present in PSD-95, Dlg, and ZO-1/2

cd00992
Location:179 → 263

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:692 → 870

Guanylate_kin; Guanylate kinase

pfam10600
Location:359 → 422

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:96 → 178

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

cl17036
Location:536 → 609

SH3; Src Homology 3 domain superfamily
XM_005165914.5 → XP_005165971.1 disks large homolog 1 isoform X25

UniProtKB/TrEMBL

A0A8M2BD88, A0A8M9QF49

Conserved Domains (7) summary

cd11861
Location:396 → 456

SH3_DLG-like; Src Homology 3 domain of Disks large homolog proteins

smart00072
Location:557 → 724

GuKc; Guanylate kinase homologues

smart00228
Location:274 → 358

PDZ; Domain present in PSD-95, Dlg, and ZO-1/2

cd00992
Location:33 → 117

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:546 → 724

Guanylate_kin; Guanylate kinase

pfam10600
Location:213 → 276

PDZ_assoc; PDZ-associated domain of NMDA receptors

pfam10608
Location:2 → 32

MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
XM_005165915.5 → XP_005165972.1 disks large homolog 1 isoform X26

UniProtKB/TrEMBL

A0A8M2BDF6

Conserved Domains (3) summary

cd11861
Location:22 → 82

SH3_DLG-like; Src Homology 3 domain of Disks large homolog proteins

smart00072
Location:183 → 350

GuKc; Guanylate kinase homologues

pfam00625
Location:172 → 350

Guanylate_kin; Guanylate kinase
XM_005165916.5 → XP_005165973.1 disks large homolog 1 isoform X27

UniProtKB/TrEMBL

A0A8M2BD83

Conserved Domains (3) summary

cd11861
Location:22 → 82

SH3_DLG-like; Src Homology 3 domain of Disks large homolog proteins

smart00072
Location:158 → 325

GuKc; Guanylate kinase homologues

pfam00625
Location:147 → 325

Guanylate_kin; Guanylate kinase