srpk1b SRSF protein kinase 1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: srpk1bprovided by ZNC
Official Full Name: SRSF protein kinase 1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-070112-2292
See related: Ensembl:ENSDARG00000031560 AllianceGenome:ZFIN:ZDB-GENE-070112-2292
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:158800
Summary: Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction; regulation of mRNA processing; and spliceosomal complex assembly. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm and nucleus. Orthologous to human SRPK1 (SRSF protein kinase 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 11

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (2763168..2828835)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (2693802..2757208)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables protein kinase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein phosphorylation	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: SRSF protein kinase 1b

Names: serine/arginine-rich protein specific kinase 1b

NP_001074138.2

EC 2.7.11.1

XP_005155715.1

EC 2.7.11.1

XP_009304041.1

EC 2.7.11.1

XP_068080327.1

EC 2.7.11.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001080669.2 → NP_001074138.2 SRSF protein kinase 1b

Status: VALIDATED

Source sequence(s)

CR318593, CT583672

UniProtKB/TrEMBL

A1L2D3

Related

ENSDARP00000042971.6, ENSDART00000042972.7

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007122.7 Reference GRCz11 Primary Assembly

Range

2763168..2828835

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009305766.4 → XP_009304041.1 SRSF protein kinase 1b isoform X2

UniProtKB/TrEMBL

A0A8M3B6N8, A1L2D3

Conserved Domains (2) summary

smart00220
Location:78 → 222

S_TKc; Serine/Threonine protein kinases, catalytic domain

cl21453
Location:68 → 254

PKc_like; Protein Kinases, catalytic domain
XM_005155658.5 → XP_005155715.1 SRSF protein kinase 1b isoform X1

UniProtKB/TrEMBL

A0A8M2B1S0, A1L2D3

Conserved Domains (2) summary

smart00220
Location:80 → 224

S_TKc; Serine/Threonine protein kinases, catalytic domain

cl21453
Location:70 → 256

PKc_like; Protein Kinases, catalytic domain
XM_068224226.1 → XP_068080327.1 SRSF protein kinase 1b isoform X3

UniProtKB/TrEMBL

A0A8M3B3T9