rab4b.S RAB4B member RAS oncogene family S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: rab4b.S
Official Full Name: RAB4B member RAS oncogene family S homeolog
Primary source: Xenbase:XB-GENE-17342705
Locus tag: XELAEV_18042536mg
See related: EnsemblRapid:ENSXLAG00005008720 AllianceGenome:Xenbase:XB-GENE-17342705
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: rab4a
Summary: Predicted to enable G protein activity and GTP binding activity. Predicted to act upstream of or within Rab protein signal transduction; protein transport; and regulation of endocytosis. Predicted to be located in early endosome membrane and plasma membrane. Orthologous to human RAB4B (RAB4B, member RAS oncogene family). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

Location:: chromosome: 8S

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	8S	NC_054386.1 (84710261..84738039)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	8S	NC_030739.1 (82332366..82360210)

Chromosome 8S - NC_054386.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables G protein activity	IEA Inferred from Electronic Annotation more info
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within Rab protein signal transduction	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of endocytosis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in early endosome membrane	IEA Inferred from Electronic Annotation more info
located_in endomembrane system	IEA Inferred from Electronic Annotation more info
located_in endosome	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: RAB4B member RAS oncogene family S homeolog

Names: RAB4A, member RAS oncogene family

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001087202.1 → NP_001080671.1 RAB4B member RAS oncogene family S homeolog

See identical proteins and their annotated locations for NP_001080671.1

Status: PROVISIONAL

Source sequence(s)

BC044974

UniProtKB/TrEMBL

A0A974C499, A0A974C7B5, Q7ZXI8

Related

ENSXLAP00005025505.1, ENSXLAT00005026216.1

Conserved Domains (2) summary

smart00175
Location:9 → 172

RAB; Rab subfamily of small GTPases

cd04113
Location:9 → 169

Rab4; Rab GTPase family 4 (Rab4)

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054386.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

84710261..84738039

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_018231881.2 → XP_018087370.1 RAB4B member RAS oncogene family S homeolog isoform X1

UniProtKB/TrEMBL

A0A974C499, A0A974C7B5, Q7ZXI8
XM_018231883.2 → XP_018087372.1 RAB4B member RAS oncogene family S homeolog isoform X2

UniProtKB/TrEMBL

A0A8J0TEK5, A0A974C7B5