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    pald1a phosphatase domain containing paladin 1a [ Danio rerio (zebrafish) ]

    Gene ID: 368369, updated on 9-Dec-2024

    Summary

    Official Symbol
    pald1aprovided by ZNC
    Official Full Name
    phosphatase domain containing paladin 1aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030804-26
    See related
    Ensembl:ENSDARG00000098946 AllianceGenome:ZFIN:ZDB-GENE-030804-26
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    pald; cb942; pald1; sb:cb559
    Summary
    Predicted to enable protein tyrosine phosphatase activity. Acts upstream of or within angiogenesis. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in several structures, including alar plate midbrain region; anterior axial hypoblast; axis; blood vessel; and central nervous system. Orthologous to human PALD1 (phosphatase domain containing paladin 1). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
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    Genomic context

    See pald1a in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (48094019..48199036, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (48110416..48289028, complement)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene A disintegrin and metalloproteinase with thrombospondin motifs 14 Neighboring gene steroidogenic acute regulatory protein 2 Neighboring gene neuropeptide FF receptor 1-like Neighboring gene nodal-related 2 Neighboring gene leucine rich repeat containing 20

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables protein tyrosine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within angiogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198811.1NP_942106.1  paladin

      See identical proteins and their annotated locations for NP_942106.1

      Status: PROVISIONAL

      Source sequence(s)
      BC044521
      UniProtKB/Swiss-Prot
      Q6NY33, Q803E0
      Related
      ENSDARP00000134468.1, ENSDART00000171058.2
      Conserved Domains (1) summary
      pfam14566
      Location:152321
      PTPlike_phytase; Inositol hexakisphosphate

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      48094019..48199036 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)