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    Zfp142 zinc finger protein 142 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 316524, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp142provided by RGD
    Official Full Name
    zinc finger protein 142provided by RGD
    Primary source
    RGD:1309648
    See related
    EnsemblRapid:ENSRNOG00000022414 AllianceGenome:RGD:1309648
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Znf142
    Summary
    Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF142 (zinc finger protein 142). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 78.5), Adrenal (RPKM 76.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp142 in Genome Data Viewer
    Location:
    9q33
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (83591318..83613896, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (76141053..76164784, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (81844138..81868086, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 37 Neighboring gene transfer RNA proline (anticodon AGG) 59 Neighboring gene CCR4-NOT transcription complex subunit 9 Neighboring gene phospholipase C, delta 4 Neighboring gene BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone Neighboring gene ring finger protein 25 Neighboring gene serine/threonine kinase 36

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 142
    Names
    zinc finger protein 142 (clone pHZ-49)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108225.2 → NP_001101695.1  zinc finger protein 142 isoform 3

      See identical proteins and their annotated locations for NP_001101695.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A6JVV2, D3ZU19
      Related
      ENSRNOP00000063907.1, ENSRNOT00000067080.4
      Conserved Domains (2) summary
      COG5048
      Location:148 → 589
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:1519 → 1540
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. NM_001431996.1 → NP_001418925.1  zinc finger protein 142 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A0A0G2JVD5

    3. NM_001431997.1 → NP_001418926.1  zinc finger protein 142 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A0A0G2JVD5

    4. NM_001431998.1 → NP_001418927.1  zinc finger protein 142 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A0A0G2JVD5

    5. NM_001431999.1 → NP_001418928.1  zinc finger protein 142 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A0A0G2JVD5

    6. NM_001432000.1 → NP_001418929.1  zinc finger protein 142 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A0A0G2JVD5

    7. NM_001432001.1 → NP_001418930.1  zinc finger protein 142 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009

    8. NM_001432002.1 → NP_001418931.1  zinc finger protein 142 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A6JVV2, D3ZU19

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      83591318..83613896 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039083678.2 → XP_038939606.1  zinc finger protein 142 isoform X2

      Conserved Domains (3) summary
      COG5048
      Location:236 → 677
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:1607 → 1628
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:1592 → 1616
      zf-H2C2_2; Zinc-finger double domain

    2. XM_063267227.1 → XP_063123297.1  zinc finger protein 142 isoform X1

      Related
      ENSRNOP00000069440.2, ENSRNOT00000084964.3

    3. XM_008767241.4 → XP_008765463.1  zinc finger protein 142 isoform X3

      Related
      ENSRNOP00000107737.1, ENSRNOT00000137794.1
      Conserved Domains (2) summary
      COG5048
      Location:163 → 604
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:1534 → 1555
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_008767242.4 → XP_008765464.1  zinc finger protein 142 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:73 → 514
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:1444 → 1465
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. XM_063267228.1 → XP_063123298.1  zinc finger protein 142 isoform X5

    Nucleotide Protein Strain
    Heading Accession and Version

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